Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Tumor Necrosis Factor-alpha/metabolism"'
Autor:
Tiemeijer, Bart M., Heester, Sebastiaan, Sturtewagen, Ashley Y.W., Smits, Anthal I.P.M., Tel, Jurjen
Publikováno v:
Frontiers in Immunology, 14:1135223. Frontiers Media S.A.
The role of macrophages in controlling tissue inflammation is indispensable to ensure a context-appropriate response to pathogens whilst preventing excessive tissue damage. Their initial response is largely characterized by high production of tumor n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ce86ba363e161693349df845f21ef2
http://www.scopus.com/inward/record.url?scp=85149838393&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85149838393&partnerID=8YFLogxK
Autor:
Mauermeir, Michael, Ölke, Martha, Hayek, Inaya, Schulze-Luehrmann, Jan, Dettmer, Katja, Oefner, Peter J., Berens, Christian, Menge, Christian, Lührmann, Anja
Background: Coxiella burnetii is a zoonotic pathogen, infecting humans, livestock, pets, birds and ticks. Domestic ruminants such as cattle, sheep, and goats are the main reservoir and major cause of human infection. Infected ruminants are usually as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4c91a10d9491c0c9e7f777d34e1d23
Autor:
Maria G. Balta, Olav Schreurs, Rashi Halder, Thomas M. Küntziger, Frank Saetre, Inger Johanne S. Blix, Espen S. Baekkevold, Enrico Glaab, Karl Schenck
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 14878
Specialized pro-resolving mediators (SPMs) are multifunctional lipid mediators that participate in the resolution of inflammation. We have recently described that oral epithelial cells (OECs) express receptors of the SPM resolvin RvD1n-3 DPA and that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1c7795c9f0e2cc3522cbc3f9b4c15c
Autor:
Andrea Polli, Jolien Hendrix, Kelly Ickmans, Jelena Bakusic, Manosij Ghosh, Dora Monteyne, Brigitte Velkeniers, Bram Bekaert, Jo Nijs, Lode Godderis
Background Catechol-O-methyltransferase (COMT) has been shown to influence clinical pain, descending modulation, and exercise-induced symptom worsening. COMT regulates nociceptive processing and inflammation, key pathophysiological features of Chroni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50fd9b008f749ca18c16760c686e131c
https://lirias.kuleuven.be/handle/20.500.12942/706328
https://lirias.kuleuven.be/handle/20.500.12942/706328
Autor:
Wang, Lei, van Iersel, Lieke E J, Pelgrim, Charlotte E, Lu, Jingyi, van Ark, Ingrid, Leusink-Muis, Thea, Gosker, Harry R, Langen, Ramon C J, Schols, Annemie M W J, Argilés, Josep M, van Helvoort, Ardy, Kraneveld, Aletta D, Garssen, Johan, Henricks, Paul A J, Folkerts, Gert, Braber, Saskia, Afd Pharmacology, Pharmacology
Publikováno v:
Cells, 11(18):2893. Multidisciplinary Digital Publishing Institute (MDPI)
Cells; Volume 11; Issue 18; Pages: 2893
Cells, 11(18), 1. Multidisciplinary Digital Publishing Institute (MDPI)
Cells, 11(18):2893. MDPI AG
Cells; Volume 11; Issue 18; Pages: 2893
Cells, 11(18), 1. Multidisciplinary Digital Publishing Institute (MDPI)
Cells, 11(18):2893. MDPI AG
Chronic obstructive pulmonary disease (COPD), often caused by smoking, is a chronic lung disease with systemic manifestations including metabolic comorbidities. This study investigates adaptive and pathological alterations in adipose and skeletal mus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dda9457573fefd081417be07f626b20
https://cris.maastrichtuniversity.nl/en/publications/a4ed5fe0-c1e3-41c3-ac22-4e5f7facbc86
https://cris.maastrichtuniversity.nl/en/publications/a4ed5fe0-c1e3-41c3-ac22-4e5f7facbc86
Autor:
Natalia Ortí-Casañ, Inge S. Zuhorn, Petrus J. W. Naudé, Peter P. De Deyn, Pauline E. M. van Schaik, Harald Wajant, Ulrich L. M. Eisel
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 119(37). NATL ACAD SCIENCES
Tumor necrosis factor-α (TNF-α) is a pleiotropic, proinflammatory cytokine related to different neurodegenerative diseases, including Alzheimer’s disease (AD). Although the linkage between increased TNF-α levels and AD is widely recognized, TNF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d246ac3edd86a222892bc0fa3ed33af
https://research.rug.nl/en/publications/ce6884f7-27c9-4de4-9608-dc561848e0b3
https://research.rug.nl/en/publications/ce6884f7-27c9-4de4-9608-dc561848e0b3
Autor:
Robert J Harris, Zena Willsmore, Roman Laddach, Silvia Crescioli, Jitesh Chauhan, Anthony Cheung, Anna Black, Jenny L. C. Geh, Alastair D MacKenzie Ross, Ciaran Healy, Sophia Tsoka, James Spicer, Katie E Lacy, Sophia N Karagiannis
Publikováno v:
Harris, R J, Willsmore, Z, Laddach, R, Crescioli, S, Chauhan, J, Cheung, A, Black, A, Geh, J L C, MacKenzie Ross, A D, Healy, C, Tsoka, S, Spicer, J, Lacy, K E & Karagiannis, S N 2022, ' Enriched circulating and tumor-resident TGF-β+ regulatory B cells in patients with melanoma promote FOXP3+ Tregs ', OncoImmunology, vol. 11, no. 1, 2104426, pp. 2104426 . https://doi.org/10.1080/2162402X.2022.2104426
B cells are emerging as key players of anti-tumor adaptive immune responses. We investigated regulatory and pro-inflammatory cytokine-expressing B cells in patients with melanoma by flow cytometric intracellular cytokine, CyTOF, transcriptomic, immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae09673c24a2cdfed4c5599d2860ce6c
https://doi.org/10.1080/2162402x.2022.2104426
https://doi.org/10.1080/2162402x.2022.2104426
Autor:
Van Du T. Tran, Gabriela Aguileta, Béatrice Desvergne, Aurélien Thomas, Nasim Bararpour, Carine Winkler, Anne Wilson, Nicolas Guex, Greta Maria Paola Giordano Attianese, Marco Pagni, Federica Gilardi, Khanh B. Trang, Tiziana Caputo
Publikováno v:
Cellular and molecular life sciences, vol. 78, no. 1, pp. 227-247
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences
Chronic inflammation that affects primarily metabolic organs, such as white adipose tissue (WAT), is considered as a major cause of human obesity-associated co-morbidities. However, the molecular mechanisms initiating this inflammation in WAT are poo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d560e66d0cd72ae04098a74c1047d7bf
https://doi.org/10.1007/s00018-020-03485-z
https://doi.org/10.1007/s00018-020-03485-z
Publikováno v:
Rafiee Tari, N, Arranz, E & Corredig, M 2019, ' Effect of protein composition of a model dairy matrix containing various levels of beta-casein on the structure and anti-inflammatory activity of in vitro digestates ', Food and Function, vol. 10, no. 4, pp. 1870-1879 . https://doi.org/10.1039/c8fo01860j
An increasing body of evidence demonstrates that differences in protein composition in the food matrix can significantly affect its biological functionality. The present research hypothesized that a matrix containing the same level of dairy protein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4175c527dd0b7a347eb66d5fd2f99e
https://doi.org/10.1039/c8fo01860j
https://doi.org/10.1039/c8fo01860j
Autor:
Antonio Sorrentino, Ayse Nur Menevse, Tillmann Michels, Valentina Volpin, Franziska Christine Durst, Julian Sax, Maria Xydia, Abir Hussein, Slava Stamova, Steffen Spoerl, Nicole Heuschneider, Jasmin Muehlbauer, Katharina Marlene Jeltsch, Anchana Rathinasamy, Melanie Werner-Klein, Marco Breinig, Damian Mikietyn, Christian Kohler, Isabel Poschke, Sabrina Purr, Olivia Reidell, Catarina Martins Freire, Rienk Offringa, Claudia Gebhard, Rainer Spang, Michael Rehli, Michael Boutros, Christian Schmidl, Nisit Khandelwal, Philipp Beckhove
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e004258
BackgroundCancer immunotherapeutic strategies showed unprecedented results in the clinic. However, many patients do not respond to immuno-oncological treatments due to the occurrence of a plethora of immunological obstacles, including tumor intrinsic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce9b03b714e0e29354c34b37a2f129d
https://doi.org/10.1136/jitc-2021-004258
https://doi.org/10.1136/jitc-2021-004258