Výsledky vyhledávání - "Tumor Necrosis Factor-alpha/ metabolism"

Progressive Control of Streptococcus agalactiae-Induced Innate Inflammatory Response Is Associated with Time Course Expression of MicroRNA-223 by Neutrophils

Autor: Georges Casimir, Maud Deny, Marta Romano, Olivier Denis, Mustapha Chamekh

Publikováno v: Infection and immunity, 88 (12
Infect Immun

Group B streptococcus (GBS) is a human-pathogenic bacterium inducing a strong inflammatory response that may be detrimental for host tissues if not finely regulated. The inflammatory response can be modulated by different molecular mechanisms, among

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497d47715aae5e5f3127dfeabce4eb56
https://doi.org/10.1128/iai.00563-20

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The activation trajectory of plasmacytoid dendritic cells in vivo during a viral infection

Autor: Jean-Luc Davignon, Karima Naciri, Rabie Chelbi, Gilles Bessou, Chuang Dong, Nils Collinet, Michael Valente, Geoffray Brelurut, Pierre Milpied, Abdenour Abbas, Morgane Thomas-Chollier, Noudjoud Attaf, Thien-Phong Vu Manh, Inaki Cervera-Marzal, Alexandra-Chloé Villani, Benjamin Rauwel, Denis Thieffry, Marc Dalod, Elena Tomasello

Publikováno v: Nature Immunology
Nature Immunology, Nature Publishing Group, 2020, 21 (9), pp.983-997. ⟨10.1038/s41590-020-0731-4⟩
Nature Immunology, 2020, 21 (9), pp.983-997. ⟨10.1038/s41590-020-0731-4⟩
Nature immunology

International audience; Plasmacytoid dendritic cells (pDCs) are a major source of type I interferon (IFN-I). What other functions pDCs exert in vivo during viral infections is controversial, and more studies are needed to understand their orchestrati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd76519d3ec2c2f1de126656bc2665f9
https://hal.archives-ouvertes.fr/hal-02980944/file/2020_11_30_Abbas_et_al_2020_accepted_manuscript_for_HAL_small_size.pdf

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Daily alcohol intake triggers aberrant synaptic pruning leading to synapse loss and anxiety-like behavior

Autor: Joana F. Henriques, Renata L. Alves, Ana Magalhães, Teresa Summavielle, Teresa Canedo, Camila C. Portugal, Cátia M. Silva, João B. Relvas, Renato Socodato, Tiago Almeida, Joana Tedim-Moreira

Alcohol abuse adversely affects the lives of millions of people worldwide. Deficits in synaptic transmission and in microglial function are commonly found in human alcohol abusers and in animal models of alcohol intoxication. Here, we found that a pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5323d1d38dd85484e38fe3dc3daa066
https://hdl.handle.net/10216/140511

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Evaluation of second trimester amniotic fluid ADAMTS4, ADAMTS5, interleukin-6 and tumor necrosis factor-α levels in patients with gestational diabetes mellitus

Autor: Osman Ciftci, Rauf Melekoglu, Ercan Nurcan Yilmaz, Ebru Celik, Ayse Gulcin Bastemur

Aim: To test the hypothesis that altered A Disintegrin and Metalloproteinase Domains with Thrombospondins motifs (ADAMTS) is implicated in the etiopathogenesis of gestational diabetes mellitus (GDM). Methods: All pregnant women who underwent elective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d970e0e847e97fe40e45e72ba775f41

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Associations between second-trimester amniotic fluid levels of ADAMTS4, ADAMTS5, IL-6, and TNF-α and spontaneous preterm delivery in singleton pregnancies

Autor: Rauf Melekoglu, Ercan Yilmaz, Yusuf Taner Kafadar, Osman Ciftci, Ebru Celik

Background We investigated the roles of inflammatory cytokines and the A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family in the etiopathogenesis of spontaneous preterm delivery by comparing the ADAMTS4, ADAMTS5, interleuk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faba3dfcf5bd20a2b99303b431c3389d

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Polarization of Rheumatoid Macrophages by TNF Targeting Through an IL-10/STAT3 Mechanism

Autor: Yannick, Degboé, Benjamin, Rauwel, Michel, Baron, Jean-Frédéric, Boyer, Adeline, Ruyssen-Witrand, Arnaud, Constantin, Jean-Luc, Davignon

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, 2019, 10, 14 p. ⟨10.3389/fimmu.2019.00003⟩

International audience; Macrophages contribute to the pathogenesis of rheumatoid arthritis (RA). They can display different states of activation or "polarization," notably the so-called inflammatory "M1" and the various alternative "M2" polarizations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::255eea046ade31aac56a2cce2a50451f
http://europepmc.org/articles/PMC6345709

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Influence of Biological Therapeutics, Cytokines, and Disease Activity on Depression in Rheumatoid Arthritis

Autor: Georgina Terroso, Brian D. Poole, Marta C. Figueiredo, Lúcia Costa, Caleb Cornaby, Margarida Figueiredo-Braga, Alice Cortez, Cristina Mesquita, Miguel Bernardes

Publikováno v: Journal of Immunology Research
Journal of Immunology Research, Vol 2018 (2018)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Purpose. Rheumatoid arthritis (RA) is an often debilitating autoinflammatory disease. Patients with rheumatoid arthritis are often troubled by co-occurring depression or other psychological manifestations. RA patients have a variety of treatment opti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9cca3cded1092375206b377f8140852
https://hdl.handle.net/10216/127051

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Mechanical versus humoral determinants of brain death-induced lung injury

Autor: Jacques Creteur, Birgit Weynand, Laurence Dewachter, Benoît Rondelet, Myriam Remmelink, Christian Melot, Asmae Belhaj, Céline Dewachter, Kathleen Mc Entee, Emeline Hupkens, Robert Naeije, Sandrine Rorive

Publikováno v: PloS one, 12 (7
PLoS ONE
PLoS One, Vol. 12, no. 7, p. e0181899 [1-22] (2017)
PLoS ONE, Vol 12, Iss 7, p e0181899 (2017)

Background: The mechanisms of brain death (BD)-induced lung injury remain incompletely understood, as uncertainties persist about time-course and relative importance of mechanical and humoral perturbations. Methods: Brain death was induced by slow in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11dc7e39cd5f2c92864e50cdb3728372
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/259258

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Mild mitochondrial uncoupling induces 3T3-L1 adipocyte de-differentiation by a PPARγ-independent mechanism, whereas TNFα-induced de-differentiation is PPARγ dependent

Autor: Françoise de Longueville, Andrée Houbion, Thierry Arnould, Aurélia De Pauw, Silvia Tejerina, Patricia Renard, Martine Raes, Sébastien Vankoningsloo

Publikováno v: Journal of Cell Science, Vol. 122, no. 1, p. 145-55 (2009)

Impairment of mitochondrial activity affects lipid-metabolizing tissues and mild mitochondrial uncoupling has been proposed as a possible strategy to fight obesity and associated diseases. In this report, we characterized the 3T3-L1-adipocyte ;de-dif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b9870e0b834418cd705038bdc74e24
https://doi.org/10.1242/jcs.027508

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