Zobrazeno 1 - 10
of 2 227
pro vyhledávání: '"Tumor Metabolism"'
Autor:
Joshua L. Katz, Yuheng Geng, Leah K. Billingham, Nishanth S. Sadagopan, Susan L. DeLay, Jay Subbiah, Tzu-yi Chia, Graysen McManus, Chao Wei, Hanxiang Wang, Hanchen Lin, Caylee Silvers, Lauren K. Boland, Si Wang, Hanxiao Wan, David Hou, Gustavo Ignacio Vázquez-Cervantes, Tarlan Arjmandi, Zainab H. Shaikh, Peng Zhang, Atique U. Ahmed, Deanna M. Tiek, Catalina Lee-Chang, Edward T. Chouchani, Jason Miska
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Glioblastoma is a Grade 4 primary brain tumor defined by therapy resistance, diffuse infiltration, and near-uniform lethality. The underlying mechanisms are unknown, and no treatment has been curative. Using a recently developed creatine kin
Externí odkaz:
https://doaj.org/article/dd7a023fe4514c80a5ab446bc7743f92
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-33 (2024)
Abstract The tumor microenvironment demonstrates great immunophenotypic heterogeneity, which has been leveraged in traditional immune-hot/cold tumor categorization based on the abundance of intra-tumoral immune cells. By incorporating the spatial imm
Externí odkaz:
https://doaj.org/article/065f947302344946abdb8593e8cd1358
Publikováno v:
SLAS Technology, Vol 29, Iss 6, Pp 100208- (2024)
Acupuncture, as a traditional Chinese medical treatment, has garnered increasing attention in recent years in fields such as tumor metabolism, the central nervous system, and the immune microenvironment. This paper aims to explore the fundamental pri
Externí odkaz:
https://doaj.org/article/3f8697aba36c41299c6ced9b4ca704fd
Autor:
Rongrong Zheng, Chuyu Huang, Hangyu Zhou, Lixin Zhao, Qiuyuan Li, Guangmiao Chen, Linping Zhao, Shiying Li
Publikováno v:
Aggregate, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract The life‐threatening colorectal cancer exhibits multilevel immunosuppressive characteristics, including low immunogenicity, abnormal cellular metabolism, and acidic immunosuppressive microenvironment. In this work, multi‐synergistic chem
Externí odkaz:
https://doaj.org/article/cdc2be6dc622492785e6514764446535
Autor:
Hongfei Guo, Yvchen Liu, Tian Wan, Da Song, Chella Perumal Palanisamy, Jingzhang Geng, Jinjin Pei, Sevilay Özmen, A.M. Abd El-Aty
Publikováno v:
Journal of Functional Foods, Vol 123, Iss , Pp 106584- (2024)
Cancer is a major global health challenge, and current treatment modalities, such as surgery, chemotherapy, radiation therapy, immunotherapy, and targeted therapies, are often associated with various adverse effects. Dietary strategies have emerged a
Externí odkaz:
https://doaj.org/article/9b757a66ef0548ae87e7f409c98feac2
Autor:
Vicent Ribas
Publikováno v:
Exploration of Digestive Diseases, Vol 3, Iss 3, Pp 203-225 (2024)
Hepatocellular carcinoma (HCC) is the most common type of liver cancer and its death rate is rising faster than that of any other cancer, while we still lack effective treatments. The increasing incidence of liver cancer in western countries is close
Externí odkaz:
https://doaj.org/article/f0659679c2c449b9bac3735b9a9c67d3
Autor:
Mohammad Sadiq Jeeyavudeen, Navin Mathiyalagan, Cornelius Fernandez James, Joseph M. Pappachan
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 5, Iss 2, Pp 349-373 (2024)
Pheochromocytomas and paragangliomas (PPGLs) have emerged as one of the most common endocrine tumors. It epitomizes fascinating crossroads of genetic, metabolic, and endocrine oncology, providing a canvas to explore the molecular intricacies of tumor
Externí odkaz:
https://doaj.org/article/07582557096c450bbfbb5f40fb4fc44c
Autor:
Shichao Yang, Caden Hu, Xiaomei Chen, Yi Tang, Juanjuan Li, Hanqing Yang, Yi Yang, Binwu Ying, Xue Xiao, Shang‑Ze Li, Li Gu, Yahui Zhu
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract It is generally recognized that tumor cells proliferate more rapidly than normal cells. Due to such an abnormally rapid proliferation rate, cancer cells constantly encounter the limits of insufficient oxygen and nutrient supplies. To satisfy
Externí odkaz:
https://doaj.org/article/0d1187fe97aa4c898e8fbb879b6881f6
Autor:
Gloria Pascual, Salvador Aznar Benitah
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Tumor cells can undergo metabolic adaptations that support their growth, invasion, and metastasis, such as reprogramming lipid metabolism to meet their energy demands and to promote survival in harsh microenvironmental conditions, including hypoxia a
Externí odkaz:
https://doaj.org/article/be52cbe77b154662bb30c6aab43e4f33
Insights into metabolic heterogeneity of colorectal cancer gained from fluorescence lifetime imaging
Autor:
Anastasia D Komarova, Snezhana D Sinyushkina, Ilia D Shchechkin, Irina N Druzhkova, Sofia A Smirnova, Vitaliy M Terekhov, Artem M Mozherov, Nadezhda I Ignatova, Elena E Nikonova, Evgeny A Shirshin, Liubov E Shimolina, Sergey V Gamayunov, Vladislav I Shcheslavskiy, Marina V Shirmanova
Publikováno v:
eLife, Vol 13 (2024)
Heterogeneity of tumor metabolism is an important, but still poorly understood aspect of tumor biology. Present work is focused on the visualization and quantification of cellular metabolic heterogeneity of colorectal cancer using fluorescence lifeti
Externí odkaz:
https://doaj.org/article/5e57f664a6284bd389556bc991227b0a