Zobrazeno 1 - 10
of 6 690
pro vyhledávání: '"Tumor Immune Microenvironment"'
Autor:
Yiting Qiao, Miao Luo, Yufei Wang, Haoxiang Qi, Menglan Wang, Yunxin Pei, Mengqing Sun, Zhengguo Zhang, Jiacheng Huang, Pengyu Gong, Shusen Zheng, Jianxiang Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 12, Pp 5418-5434 (2024)
Specific tumor-targeted gene delivery remains an unsolved therapeutic issue due to aberrant vascularization in tumor microenvironment (TME). Some bacteria exhibit spontaneous chemotaxis toward the anaerobic and immune-suppressive TME, which makes the
Externí odkaz:
https://doaj.org/article/bb67f3192552430db9bcd7f982a7f7d7
Publikováno v:
Cell Adhesion & Migration, Vol 18, Iss 1, Pp 1-17 (2024)
Molecule interacting with CasL 1 (MICAL1) is a crucial protein involved in cell motility, axon guidance, cytoskeletal dynamics, and gene transcription. This pan-cancer study analyzed MICAL1 across 33 cancer types using bioinformatics and experiments.
Externí odkaz:
https://doaj.org/article/76aff67239cb44c5b94de401e77f96cf
Autor:
Lijun Xu, Lei Yang, Dan Zhang, Yunxi Wu, Jiali Shan, Huixia Zhu, Zhengyi Lian, Guying He, Chongyu Wang, Qingqing Wang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1201-1213 (2024)
Background: Cuproptosis, i.e., copper-induced programmed cell death, has potential implications in cancer therapy. However, the impact of the cuproptosis-related gene (CRG) dihydrolipoyl dehydrogenase (DLD) on breast cancer (BC) prognosis remains und
Externí odkaz:
https://doaj.org/article/5f7faefe158a4b94ab36584c5c8899fa
Autor:
Chao Hu, Qingzhou Li, Lei Xiang, Yan Luo, Shengrong Li, Jun An, Xiankuo Yu, Guochen Zhang, Yuhui Chen, Yumei Wang, Dong Wang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 234-250 (2024)
TRIB3, a pseudokinase, was previously studied within only some specific cancer types, leaving its comprehensive functions in pan-cancer contexts largely unexplored. Here, we performed an integrated analysis of TRIB3 expression, prognosis, genetic alt
Externí odkaz:
https://doaj.org/article/6eb9b5b50a194e34b47da794898e15e0
Autor:
Yuan Tian, Shenghui Qiu, Song Yang, Yuanjian Jiang, Hao Hu, Chengcheng Yang, Jinyong Cao, Shaomin Chen, Mingqing Hao, Hongling Li, Jianlin Zhu
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Stomach adenocarcinoma (STAD) is known for its high prevalence and poor prognosis, which underscores the need for novel therapeutic targets. Peroxidasin (PXDN), an enzyme with peroxidase activity, has been linked to cancer development in pre
Externí odkaz:
https://doaj.org/article/1b7a11bbee9846999b42e995b77d5e5f
Autor:
Hao Duan, Jianlan Ren, Shiyou Wei, Zhenyu Yang, Chuan Li, Zhenning Wang, Meichen Li, Zhi Wei, Yu Liu, Xiuqi Wang, Hongbin Lan, Zhen Zeng, Maodi Xie, Yuan Xie, Suwen Wu, Wanming Hu, Chengcheng Guo, Xiangheng Zhang, Lun Liang, Chengwei Yu, Yanhao Mou, Yu Jiang, Houde Li, Eric Sugarman, Rebecca A. Deek, Zexin Chen, Tao Li, Yaohui Chen, Maojin Yao, Likun Chen, Lunxu Liu, Gao Zhang, Yonggao Mou
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-30 (2024)
Abstract Background Lung cancer brain metastases (LC-BrMs) are frequently associated with dismal mortality rates in patients with lung cancer; however, standard of care therapies for LC-BrMs are still limited in their efficacy. A deep understanding o
Externí odkaz:
https://doaj.org/article/6ef9a97ee27d43c4b25d89dca7b5e524
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-18 (2024)
Abstract Background Previous studies have reported that the tumor immune microenvironment (TIME) was associated with the prognosis of lung cancer patients and the efficacy of immunotherapy. However, given the significant challenges in obtaining speci
Externí odkaz:
https://doaj.org/article/25183cfe69af44d9973f97d64a20ac43
Publikováno v:
Cancer Management and Research, Vol Volume 16, Pp 1663-1683 (2024)
YuanLi Huang,1 JinJie Liu,1,2 ChunLian Lin,1,2 Qing Zhu,1,3 LiGao Wu1,3 1Department of Pathology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, People’s Republic of China; 2Graduate School of Bengbu Medical University,
Externí odkaz:
https://doaj.org/article/97d70253b05347e0bdecc5591d1c29cd
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 9511-9525 (2024)
Lukun Yang,1,2,* Ling Li,3,* Peiping Li,1,* Jiafan Chen,1 Chaonong Cai,1 Yingbin Jia,1 Jian Li,1 Baojia Zou1 1Department of Hepatobiliary Surgery, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong Province, People
Externí odkaz:
https://doaj.org/article/428726008ca740479465190ca5ab6533
Autor:
Shirong Ding, Ruozhu Yang, Jiahao Meng, Xinyu Guan, Yue Hong, Jiachi Xu, Limeng Qu, Jingfen Ji, Wenjun Yi, Qiongyan Zou, Qian Long
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Indoleamine 2,3-dioxygenase 1 (IDO1) plays an important role in the initiation and progression of breast cancer. DNA promoter methylation status has the potential to be used as a biomarker for predicting the response to immunotherapy. This s
Externí odkaz:
https://doaj.org/article/9950e7b80f2d4d52be9e7b914f1f83fe