Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tumor Biology/Models (TB)"'
Autor:
Noriyuki Kijima, Daisuke Kanematsu, Tomoko Shofuda, Ema Yoshioka, Atsuyo Yamamoto, Yukako Handa, Hayato Fukusumi, Asako Katsuma, Miho Sumida, Shusuke Moriuchi, Masahiro Nonaka, Yoshiko Okita, Naohiro Tsuyuguchi, Takehiro Uda, Toshiyuki Kawashima, Junya Fukai, Yoshinori Kodama, Masayuki Mano, Yuichiro Higuchi, Hiroshi Suemizu, Yonehiro Kanemura
Publikováno v:
Neuro-oncology Advances
Long-term proliferating tumorsphere-forming glioma derived cells (LTP-TS-GDCs) and patient derived xenografts (PDXs) are essential tools for translational research for glioma. However, only small subsets of glioma samples are established as LTP-TS an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95aaab869bae382fd8429ab7b46ce83
http://europepmc.org/articles/PMC8648216
http://europepmc.org/articles/PMC8648216
Autor:
Mineharu, Yohei, Matsui, Yasuzumi, Oichi, Yuki, Kamata, Takahiko, Morimoto, Takaaki, Nakao, Tetsushi, Horie, Takahiro, Ono, Koh, Terada, Yokinori, Tanji, Masahiro, Arakawa, Yoshiki, Miyamoto, Susumu
Publikováno v:
Neuro-oncology Advances
Background and purposes: Lipid metabolism have been shown to be associated with tumorigenicity in various malignancies. The purpose of this study was to investigate the association of miR-33, a key regulator of lipid metabolism, in tumorigenicity and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b300f4b2b65a09efeafe859152fbbcce
https://doi.org/10.1093/noajnl/vdab159.021
https://doi.org/10.1093/noajnl/vdab159.021
Autor:
Fujii, Takashi, Yamamuro, Shun, Takahashi, Masamichi, Kondo, Akihide, Narita, Yoshitaka, Yoshino, Atsuo, Wada, Kojiro, Ichimura, Koichi, Tomiyama, Arata
Publikováno v:
Neuro-oncology Advances
The therapeutic outcome of glioblastomas (GBMs) is still very poor. Therefore, invention of novel therapeutic methods against GBM cases is considered urgent. The antitumor effects of naturally-derived compounds are attracting attention recently, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f312975d03f4e2c5bc887d7644b7a410
https://doi.org/10.1093/noajnl/vdab159.022
https://doi.org/10.1093/noajnl/vdab159.022
Autor:
Hideki Kuroda, Noriyuki Kijima, Tomoyoshi Nakagawa, Ryuichi Hirayama, Yoshiko Okita, Naoki Kagawa, Haruhiko Kisima
Publikováno v:
Neuro-oncology Advances
Background: Molecular heterogeneity among and within tumors are one of the reasons for the poor survival rate of brain tumors even with the current standard therapy. However, monolayer culture and neuro-sphere culture (NS) use exogenous growth factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a09e15577a53797247c26f03a8c9d95a
http://europepmc.org/articles/PMC8648242
http://europepmc.org/articles/PMC8648242
Autor:
Kohei Yoshimura, Hideki Kashiwagi, Shinji Kawabata, Yusuke Fukuo, Koji Takeuchi, Ryo Hiramatsu, Naonori Hu, Hiroki Tanaka, Minoru Suzuki, Shin-Ichi Miyatake, Masahiko Wanibuchi
Publikováno v:
Neuro-oncology Advances
Background: High-dose methotrexate and whole brain radiation therapy (WBRT) is the recommended treatment for primary central nervous system lymphoma (PCNSL). Although the initial treatment is successful, the recurrence rate is high and the prognosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88e1cc6beef153869bd4410708aa167c
http://europepmc.org/articles/PMC8648232
http://europepmc.org/articles/PMC8648232
Autor:
Shinji Yamashita, Hideo Takeshima, Kiyotaka Yokogami, Takashi Watanabe, Asako Mizuguchi, Go Takeishi
Publikováno v:
Neuro-oncology Advances
Background: Since most pituitary adenomas are benign, there is no model of pituitary adenomas that can be continuously cultured without genetic manipulation. In this study, we analyzed the genetic characteristics of the established cell lines by cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39069a7a55ecc783d21433f6ec992971
https://doi.org/10.1093/noajnl/vdaa143.028
https://doi.org/10.1093/noajnl/vdaa143.028
Autor:
Kosuke Aoki, Kuniaki Tanahashi, Toshihiko Wakabayashi, Yukihiro Shiraki, Kazuya Motomura, Yotaro Kitano, Shintaro Yamazaki, Sachi Maeda, Hiroyuki Shimizu, Fumiharu Ohka, Junya Yamaguchi, Atsushi Enomoto, Kazuhito Takeuchi, Masaki Hirano, Atsushi Natsume
Publikováno v:
Neuro-oncology Advances
Meningioma is the most frequently occurring intracranial neoplasms in adults. Tumor removal surgery and radiotherapy were the widely accepted standard treatment for meningioma. Most meningioma cases were cured by extended total removal. However, some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a864025ef769363739beda51e2c53fee
https://doi.org/10.1093/noajnl/vdaa143.029
https://doi.org/10.1093/noajnl/vdaa143.029
Autor:
Masamichi Takahashi, Mami Yasukawa, Tomoyuki Nakano, Taketoshi Maehara, Koichi Ichimura, Arata Tomiyama, Kenji Fujimoto, Takamune Achiha, Kenkichi Masutomi, Hideyuki Arita
Publikováno v:
Neuro-oncology Advances
Meningioma is the most common intracranial tumor, and its prognosis is typically favorable. However, patients of malignant meningioma (WHO grade III) most often experience recurrence, undergo multiple surgical treatments, and have poor prognosis. No
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47c4c249506e4bc5e6bc35db1092c4b
http://europepmc.org/articles/PMC7699056
http://europepmc.org/articles/PMC7699056
Autor:
Shigeta Miyake, Taishi Nakamura, Shinichirou Matsuyama, Takashi Yamamoto, Joe Sasame, Kensuke Tateishi, Yohei Miyake
Publikováno v:
Neuro-oncology Advances
INTRODUCTION Alkylating agents, including Temozolomide (TMZ) and CCNU (ACNU) have been widely accepted as a standard treatment in malignant gliomas. Several studies also demonstrated that BCNU wafer placement extended survival in glioblastoma patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b0c6a4f3de89f96aa8d8473dcacc27
http://europepmc.org/articles/PMC7213408
http://europepmc.org/articles/PMC7213408
Autor:
Yusuke Fukuo, Shinji Kawabata, Kouji Ono, Takuya Kanemitsu, Kouji Takeuchi, Shin-Ichi Miyatake, Masahiko Wanibuchi, Ryo Hiramatsu, Hideki Kashiwagi
Publikováno v:
Neuro-oncology Advances
INTRODUCTION Boron neutron capture therapy (BNCT) is form of tumor-cell selective particle irradiation. Although novel boron compounds have been developed, BPA (boronophenylalanine) and BSH (borocaptate sodium) are used in the clinical practice. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba8b4b721a8f3144983f9d0969330813
https://doi.org/10.1093/noajnl/vdz039.046
https://doi.org/10.1093/noajnl/vdz039.046