Zobrazeno 1 - 10
of 4 383
pro vyhledávání: '"Tumor Biology"'
Autor:
Jason Tasoulas, Travis P. Schrank, Harish Bharambe, Jay Mehta, Steven Johnson, Kimon Divaris, Trevor G. Hackman, Siddharth Sheth, Kedar Kirtane, Juan C. Hernandez-Prera, Christine H. Chung, Wendell G. Yarbrough, Renata Ferrarotto, Natalia Issaeva, Stamatios Theocharis, Antonio L. Amelio
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Adenoid cystic carcinoma (AdCC) is a slow-growing salivary gland malignancy that relapses frequently. AdCCs of the submandibular gland exhibit unique differences in prognosis and treatment response to adjuvant radiotherapy compared to other
Externí odkaz:
https://doaj.org/article/dcc8fd92e705442c9ebdfb5df85e4bce
Autor:
Alexandra R. Harris, Tengteng Wang, Yujing J. Heng, Gabrielle M. Baker, Phuong Anh Le, Jun Wang, Christine Ambrosone, Adam Brufsky, Fergus J. Couch, Francesmary Modugno, Christopher G. Scott, Celine M. Vachon, Susan E. Hankinson, Bernard A. Rosner, Rulla M. Tamimi, Cheng Peng, A. Heather Eliassen
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-14 (2024)
Abstract Background Early menarche is an established risk factor for breast cancer but its molecular contribution to tumor biology and prognosis remains unclear. Methods We profiled transcriptome-wide gene expression in breast tumors (N = 846) and tu
Externí odkaz:
https://doaj.org/article/76b5bacfbc8949afa92769f09a2daa34
Publikováno v:
Experimental Biology and Medicine, Vol 249 (2024)
Fructose and lactate are present in high concentrations in uterine luminal fluid, fetal fluids and fetal blood of ungulates and cetaceans, but their roles have been ignored and they have been considered waste products of pregnancy. This review provid
Externí odkaz:
https://doaj.org/article/d68a411a98de4e3c8bf1faa525292a27
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract N6-methyladenosine (m6A) stands as the most prevalent modified form of RNA in eukaryotes, pivotal in various biological processes such as regulating RNA stability, translation, and transcription. All members within the YT521-B homology (YTH)
Externí odkaz:
https://doaj.org/article/9d7ac15c14f749979969da53d6e360e5
Autor:
Siyu Li, Ningjing Lei, Mengyu Chen, Ruixia Guo, Liping Han, Luojie Qiu, Fengling Wu, Shan Jiang, Ningyao Tong, Kunmei Wang, Yong Li, Lei Chang
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102130- (2024)
Ovarian cancer is a highly heterogeneous tumor with a poor prognosis. The lack of reliable and efficient research models that can accurately mimic heterogeneity has impeded in-depth investigations and hindered the clinical translation of research fin
Externí odkaz:
https://doaj.org/article/eda43a99a4ba4f79940cc2ec6a315fc8
Autor:
Michael Grant, Lian Ni Lee, Senthil Chinnakannan, Orion Tong, Jonathan Kwok, Nicole Cianci, Luke Tillman, Abhishek Saha, Vinnycius Pereira Almeida, Carol Leung
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTCancer is a global health challenge, with changing demographics and lifestyle factors producing an increasing burden worldwide. Screening advancements are enabling earlier diagnoses, but current cancer immunotherapies only induce remission in
Externí odkaz:
https://doaj.org/article/2063d6422adc4b1d89ff15bd2bb2b2e8
Autor:
Justus Kaufmann, Maximilian Haist, Ivan-Maximiliano Kur, Stefanie Zimmer, Jan Hagemann, Christoph Matthias, Stephan Grabbe, Heinz Schmidberger, Andreas Weigert, Arnulf Mayer
Publikováno v:
Translational Oncology, Vol 46, Iss , Pp 102019- (2024)
The growth pattern of oropharyngeal squamous cell carcinomas (OPSCC) varies from compact tumor cell aggregates to diffusely infiltrating tumor cell-clusters. The influence of the growth pattern on local tumor control and survival has been studied mai
Externí odkaz:
https://doaj.org/article/00464a0c31cb415aa53bf4a1c2be142f
Autor:
Kajsa Björner, Wei-Na Chen, Venkata Ram Gannavarapu, Fredrik Axling, Miklos Gulyas, Mohammad Abdul Halim, Dominic-Luc Webb, Per M. Hellström
Publikováno v:
Upsala Journal of Medical Sciences, Vol 28, Iss 0, Pp 1-9 (2024)
Background: Inflammatory bowel disease (IBD; mainly ulcerative colitis and Crohn’s disease) is associated with the development of colorectal cancer (CRC) referred to as colitis-associated colorectal cancer (CAC). In inflammatory flares of IBD, the
Externí odkaz:
https://doaj.org/article/4eb58f1facbf47a6b752711a291b8b67
Autor:
Völundur Hafstað, Jari Häkkinen, Malin Larsson, Johan Staaf, Johan Vallon-Christersson, Helena Persson
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Background Genomic rearrangements in cancer cells can create fusion genes that encode chimeric proteins or alter the expression of coding and non-coding RNAs. In some cancer types, fusions involving specific kinases are used as targets for t
Externí odkaz:
https://doaj.org/article/9ff2da0262514696b39df8415e9a8fba
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1389 (2024)
Hypoxia is a crucial factor in tumor biology, affecting various solid tumors to different extents. Its influence spans both early and advanced stages of cancer, altering cellular functions and promoting resistance to therapy. Hypoxia reduces the effe
Externí odkaz:
https://doaj.org/article/7540d72d24674f04bd1372b5db9fb991