Zobrazeno 1 - 10
of 2 826
pro vyhledávání: '"Tumor‐associated antigen"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionETAA1 is recruited to DNA damage sites via its RPA -binding and ATR -activating domain (AAD) motifs, where RPA binding is crucial for ETAA1’s regulation of ATR activity. Methods & resultsOur findings associate Programmed Death- Ligand1
Externí odkaz:
https://doaj.org/article/ff0bf2aef5d24c68a91d99b114d92ea9
Publikováno v:
Advanced Science, Vol 11, Iss 36, Pp n/a-n/a (2024)
Abstract Clinical translation of current cancer vaccine research has been hampered by limited antitumor immune responses due to inefficient antigen delivery and presentation, suboptimal DC and T cell activation. Biomaterial‐based nanovaccine offers
Externí odkaz:
https://doaj.org/article/a0d6b6aaab604496b38241737ca8d6b6
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Multiple myeloma (MM) is a hematological cancer marked by plasma cell accumulation in the bone marrow. Despite treatment advancements, MM remains incurable in most patients. MM-associated immune dysregulation fosters disease progression, prompting re
Externí odkaz:
https://doaj.org/article/5fd886a9599348fdb6af9e263f0f2545
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33888- (2024)
Background: Single Tumor-associated autoantibodies (TAAbs) and tumor-associated antigens (TAAs) have been found to have lower diagnostic efficacy in lung cancer. Our objective is to develop and validate a lung cancer prediction model that utilizes TA
Externí odkaz:
https://doaj.org/article/19368a7b0db2411682bba5ab661bb763
Autor:
Concetta Ragone, Angela Mauriello, Beatrice Cavalluzzo, Ernesta Cavalcanti, Luigi Russo, Carmen Manolio, Simona Mangano, Biancamaria Cembrola, Maria Tagliamonte, Luigi Buonaguro
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundIn the present study we investigated whether peptides derived from the entire SARS-CoV-2 proteome share homology to TAAs (tumor-associated antigens) and cross-reactive CD8+ T cell can be elicited by the BNT162b2 preventive vaccine or the SA
Externí odkaz:
https://doaj.org/article/bb9403ce72c24b2db887c1f182e6c1fd
Autor:
Anna Valerevna Gorodilova, Kristina Viktorovna Kitaeva, Ivan Yurevich Filin, Yuri Pavlovich Mayasin, Chulpan Bulatovna Kharisova, Shaza S. Issa, Valeriya Vladimirovna Solovyeva, Albert Anatolyevich Rizvanov
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 10, Pp 8053-8070 (2023)
Since the discovery of dendritic cells (DCs) in 1973 by Ralph Steinman, a tremendous amount of knowledge regarding these innate immunity cells has been accumulating. Their role in regulating both innate and adaptive immune processes is gradually bein
Externí odkaz:
https://doaj.org/article/22871e74ae8f48e39c2467d4388602df
Autor:
Samaneh Tokhanbigli, Helia Alavifard, Hamid Asadzadeh Aghdaei, Mohammad Reza Zali, Kaveh Baghaei
Publikováno v:
BioImpacts, Vol 13, Iss 4, Pp 333-346 (2023)
Introduction: The maturation faith of dendritic cells is restrained by the inflammatory environment and cytokines, such as interleukin-6 and its downstream component. Therefore, introducing the suitable antigen to dendritic cells is crucial. However,
Externí odkaz:
https://doaj.org/article/c6e2ade2341f4e5e868e658d0c4f1807
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-20 (2023)
Abstract Immune cell engagers are engineered antibodies with at least one arm binding a tumor-associated antigen and at least another one directed against an activating receptor in immune effector cells: CD3 for recruitment of T cells and CD16a for N
Externí odkaz:
https://doaj.org/article/753183316192449f81abf0e45f4814e5
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Objective The discovery and characterization of tumor associated antigens is increasingly important to advance the field of immuno-oncology. In this regard, labyrinthin has been implicated as a neoantigen found on the cell surface of adenoca
Externí odkaz:
https://doaj.org/article/7a5e6d2c90f04a4b9ccd7548bb911185