‘Big Data’ informed drug development: a case for acceptability

Autor: Desai, Neel, Edwards, A.J., Ernest, T.B., Tuleu, C., Orlu, M.

Publikováno v: In Drug Discovery Today April 2021 26(4):865-869

Children's Preferences for Oral Dosage Forms and Their Involvement in Formulation Research via EPTRI (European Paediatric Translational Research Infrastructure)

Autor: Alessandrini E, Brako F, Scarpa M, Lupo M, Bonifazi D, Pignataro V, Cavallo M, Cullufe O, Enache C, Nafria-Escalera B, Claverol J, De Taeye L, Vermeulen E, Preston J, Tuleu C

Publikováno v: Pharmaceutics
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Universidad de Alicante (UA)
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

The paucity of evidence-based data on formulation characteristics preferred by the children is known to limit the design of tailored paediatric dosage forms. The European Paediatric Translational Research Infrastructure (EPTRI) commissioned a study t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::17896631c899c8fcf4702e6ead404b95
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=19564

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New generalized poisson mixture model for bimodal count data with drug effect: An application to rodent brief‐access taste aversion experiments

Autor: Sheng, Y, Soto, J, Orlu Gul, M, Cortina‐Borja, M, Tuleu, C, Standing, JF

Publikováno v: CPT: Pharmacometrics & Systems Pharmacology

Pharmacodynamic (PD) count data can exhibit bimodality and nonequidispersion complicating the inclusion of drug effect. The purpose of this study was to explore four different mixture distribution models for bimodal count data by including both drug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b9ec6231c0fe04fdbcdf1399c094f99a
http://europepmc.org/articles/PMC4999606

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