Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tulasikumari, Kanipakala"'
Autor:
Yu Wang, Ipsita Mukherjee, Arundhathi Venkatasubramaniam, Dustin Dikeman, Nicholas Orlando, Jing Zhang, Roger Ortines, Mark Mednikov, Shardulendra P. Sherchand, Tulasikumari Kanipakala, Thao Le, Sanjay Shukla, Mark Ketner, Rajan P. Adhikari, Hatice Karauzum, M. Javad Aman, Nathan K. Archer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Staphylococcus aureus is the leading cause of skin and soft tissue infections (SSTIs) in the U.S. as well as more serious invasive diseases, including bacteremia, sepsis, endocarditis, surgical site infections, osteomyelitis, and pneumonia. These inf
Externí odkaz:
https://doaj.org/article/9e8670e1737d41c3b9440e011a2c6162
Autor:
Shweta Kailasan, Ravi Kant, Madeleine Noonan-Shueh, Tulasikumari Kanipakala, Grant Liao, Sergey Shulenin, Daisy W. Leung, Richard A. Alm, Rajan P. Adhikari, Gaya K. Amarasinghe, Michael L. Gross, M. Javad Aman
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Staphylococcus aureus carries an exceptional repertoire of virulence factors that aid in immune evasion. Previous single-target approaches for S. aureus-specific vaccines and monoclonal antibodies (mAbs) have failed in clinical trials due to the mult
Externí odkaz:
https://doaj.org/article/536d0a35d34246f88a85754222c857ae
Autor:
Shardulendra Prasad Sherchand, Rajan P. Adhikari, Gowrishankar Muthukrishnan, Tulasikumari Kanipakala, John R. Owen, Chao Xie, M. Javad Aman, Richard A. Proctor, Edward M. Schwarz, Stephen L. Kates
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Staphylococcus aureus osteomyelitis remains a very challenging condition; recent clinical studies have shown infection control rates following surgery/antibiotics to be ~60%. Additionally, prior efforts to produce an effective S. aureus vaccine have
Externí odkaz:
https://doaj.org/article/86befead12a24ee4bec39e7017d85dbf
Autor:
Xiaobing Han, Roger Ortines, Ipsita Mukherjee, Tulasikumari Kanipakala, Thomas Kort, Shardulendra P. Sherchand, Grant Liao, Mark Mednikov, Agnes L. Chenine, M. Javad Aman, Cory L. Nykiforuk, Rajan P. Adhikari
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Staphylococcus aureus has been acquiring multiple drug resistance and has evolved into superbugs such as Methicillin/Vancomycin-resistant S. aureus (MRSA/VRSA) and, consequently, is a major cause of nosocomial and community infections associated with
Externí odkaz:
https://doaj.org/article/8ed38ad2e8f142c89e8bcb9df02022af
Autor:
Shweta Kailasan, Thomas Kort, Ipsita Mukherjee, Grant C. Liao, Tulasikumari Kanipakala, Nils Williston, Nader Ganjbaksh, Arundhathi Venkatasubramaniam, Frederick W. Holtsberg, Hatice Karauzum, Rajan P. Adhikari, M. Javad Aman
Publikováno v:
Toxins, Vol 11, Iss 6, p 339 (2019)
Staphylococcus aureus (SA) infections cause high mortality and morbidity in humans. Being central to its pathogenesis, S. aureus thwarts the host defense by secreting a myriad of virulence factors, including bicomponent, pore-forming leukotoxins. Whi
Externí odkaz:
https://doaj.org/article/c6f398503f794613afe09b6beeb975f9
Autor:
Shweta, Kailasan, Ravi, Kant, Madeleine, Noonan-Shueh, Tulasikumari, Kanipakala, Grant, Liao, Sergey, Shulenin, Daisy W, Leung, Richard A, Alm, Rajan P, Adhikari, Gaya K, Amarasinghe, Michael L, Gross, M Javad, Aman
Publikováno v:
mAbs. 14(1)
Autor:
Arundhathi Venkatasubramaniam, Tulasikumari Kanipakala, Nader Ganjbaksh, Rana Mehr, Ipsita Mukherjee, Subramaniam Krishnan, Taeok Bae, M. Javad Aman, Rajan P. Adhikari
Publikováno v:
Toxins, Vol 10, Iss 9, p 377 (2018)
Cytolytic pore-forming toxins including alpha hemolysin (Hla) and bicomponent leukotoxins play an important role in the pathogenesis of Staphylococcus aureus. These toxins kill the polymorphonuclear phagocytes (PMNs), disrupt epithelial and endotheli
Externí odkaz:
https://doaj.org/article/01773acd6cfc48c680475e846cd4cf50
Autor:
Rajan P Adhikari, Thomas Kort, Sergey Shulenin, Tulasikumari Kanipakala, Nader Ganjbaksh, Mary-Claire Roghmann, Frederick W Holtsberg, M Javad Aman
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143493 (2015)
Externí odkaz:
https://doaj.org/article/f4fd3f3f06514695a4138cab9c85a052
Autor:
Rajan P Adhikari, Thomas Kort, Sergey Shulenin, Tulasikumari Kanipakala, Nader Ganjbaksh, Mary-Claire Roghmann, Frederick W Holtsberg, M Javad Aman
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137874 (2015)
S. aureus vaccine development has proven particularly difficult. The conventional approach to achieve sterile immunity through opsonophagocytic killing has been largely unsuccessful. S. aureus is highly toxigenic and a great body of evidence suggests
Externí odkaz:
https://doaj.org/article/e30c3539d13c4c208ba54b1ee10590e9
Autor:
M. Javad Aman, Arundhathi Venkatasubramaniam, Nader Ganjbaksh, Shweta Kailasan, Hatice Karauzum, Rajan P. Adhikari, Ipsita Mukherjee, Tulasikumari Kanipakala, Grant C. Liao, Williston Nils, Thomas Kort, Frederick W. Holtsberg
Publikováno v:
Toxins, Vol 11, Iss 6, p 339 (2019)
Toxins
Volume 11
Issue 6
Toxins
Volume 11
Issue 6
Staphylococcus aureus (SA) infections cause high mortality and morbidity in humans. Being central to its pathogenesis, S. aureus thwarts the host defense by secreting a myriad of virulence factors, including bicomponent, pore-forming leukotoxins. Whi