Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Tukiet T Lam"'
Autor:
Erica L Gorenberg, Sofia Massaro Tieze, Betül Yücel, Helen R Zhao, Vicky Chou, Gregory S Wirak, Susumu Tomita, TuKiet T Lam, Sreeganga S Chandra
Publikováno v:
PLoS Biology, Vol 20, Iss 3, p e3001590 (2022)
Loss-of-function mutations in the depalmitoylating enzyme palmitoyl protein thioesterase 1 (PPT1) cause neuronal ceroid lipofuscinosis (NCL), a devastating neurodegenerative disease. The substrates of PPT1 are largely undescribed, posing a limitation
Externí odkaz:
https://doaj.org/article/2b17440e1d874180bbcb43c2eb4e0aab
Publikováno v:
PLoS Pathogens, Vol 15, Iss 8, p e1007980 (2019)
Almost one third of herpesvirus proteins are expressed with late kinetics. Many of these late proteins serve crucial structural functions such as formation of virus particles, attachment to host cells and internalization. Recently, we and others iden
Externí odkaz:
https://doaj.org/article/4a6f50aed9fa4c9aa5f4da2580090de9
Autor:
Ata M Kiapour, Jakob T Sieker, Benedikt L Proffen, TuKiet T Lam, Braden C Fleming, Martha M Murray
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0212662 (2019)
Surgical transection of the anterior cruciate ligament (ACL) in the porcine model leads to posttraumatic osteoarthritis if left untreated. However, a recently developed surgical treatment, bridge-enhanced ACL repair, prevents further cartilage damage
Externí odkaz:
https://doaj.org/article/22d92fd719cd4d7290838995a8b1dae6
Autor:
Lisa N Glass, Ganduri Swapna, Sivagami Sundaram Chavadi, JoAnn M Tufariello, Kaixia Mi, Joshua E Drumm, TuKiet T Lam, Guofeng Zhu, Chenyang Zhan, Catherine Vilchéze, Jesus Arcos, Yong Chen, Lijun Bi, Simren Mehta, Steven A Porcelli, Steve C Almo, Syun-Ru Yeh, William R Jacobs, Jordi B Torrelles, John Chan
Publikováno v:
PLoS Pathogens, Vol 13, Iss 7, p e1006515 (2017)
We have previously shown that the Mycobacterium tuberculosis universal stress protein Rv2623 regulates mycobacterial growth and may be required for the establishment of tuberculous persistence. Here, yeast two-hybrid and affinity chromatography exper
Externí odkaz:
https://doaj.org/article/6d48c6ed73d94b888c9e8814f3059ad9
Publikováno v:
Biomarker Insights, Vol 12 (2017)
A data-independent acquisition (DIA)/parallel reaction monitoring (PRM) workflow was implemented to identify improved ovarian cancer biomarkers. Data-independent acquisition on ovarian cancer versus control sera and literature searches identified 50
Externí odkaz:
https://doaj.org/article/e10fd24bb6f44626a0bd271ffbe0b507
Autor:
Veronica Musante, Lu Li, Jean Kanyo, Tukiet T Lam, Christopher M Colangelo, Shuk Kei Cheng, A Harrison Brody, Paul Greengard, Nicolas Le Novère, Angus C Nairn
Publikováno v:
eLife, Vol 6 (2017)
ARPP-16, ARPP-19, and ENSA are inhibitors of protein phosphatase PP2A. ARPP-19 and ENSA phosphorylated by Greatwall kinase inhibit PP2A during mitosis. ARPP-16 is expressed in striatal neurons where basal phosphorylation by MAST3 kinase inhibits PP2A
Externí odkaz:
https://doaj.org/article/1c6cbe02d5e743ca833ba86d9c17d590
Autor:
Simon J. Pelletier, Mickaël Leclercq, Florence Roux-Dalvai, Matthijs B. de Geus, Shannon Leslie, Weiwei Wang, TuKiet T. Lam, Angus C. Nairn, Steven E. Arnold, Becky C. Carlyle, Frédéric Precioso, Arnaud Droit
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Liquid Chromatography Mass Spectrometry (LC-MS) is a powerful method for profiling complex biological samples. However, batch effects typically arise from differences in sample processing protocols, experimental conditions, and data acquisit
Externí odkaz:
https://doaj.org/article/f411488984d94091a9e476c56116f06f
Autor:
Jian Xu, Manavi Chatterjee, Tyler D Baguley, Jonathan Brouillette, Pradeep Kurup, Debolina Ghosh, Jean Kanyo, Yang Zhang, Kathleen Seyb, Chimezie Ononenyi, Ethan Foscue, George M Anderson, Jodi Gresack, Gregory D Cuny, Marcie A Glicksman, Paul Greengard, TuKiet T Lam, Lutz Tautz, Angus C Nairn, Jonathan A Ellman, Paul J Lombroso
Publikováno v:
PLoS Biology, Vol 12, Iss 8, p e1001923 (2014)
STEP (STriatal-Enriched protein tyrosine Phosphatase) is a neuron-specific phosphatase that regulates N-methyl-D-aspartate receptor (NMDAR) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) trafficking, as well as ERK1/2, p38
Externí odkaz:
https://doaj.org/article/464c724e9a9e498caf07c3427d02b23b
Autor:
Valeria Lallai, TuKiet T. Lam, Rolando Garcia-Milian, Yen-Chu Chen, James P. Fowler, Letizia Manca, Daniele Piomelli, Kenneth Williams, Angus C. Nairn, Christie D. Fowler
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1143 (2024)
Given the increasing use of cannabis in the US, there is an urgent need to better understand the drug’s effects on central signaling mechanisms. Extracellular vesicles (EVs) have been identified as intercellular signaling mediators that contain a v
Externí odkaz:
https://doaj.org/article/8a5e8ff0fc664decb38c759a33e11e57
Autor:
Mei-Ling Yang, TuKiet T. Lam, Jean Kanyo, Insoo Kang, Zhaohui Sunny Zhou, Steven G. Clarke, Mark J. Mamula
Publikováno v:
Autoimmunity, Vol 56, Iss 1 (2023)
AbstractProtein posttranslational modifications (PTMs) arise in a number of normal cellular biological pathways and in response to pathology caused by inflammation and/or infection. Indeed, a number of PTMs have been identified and linked to specific
Externí odkaz:
https://doaj.org/article/66aeaf4b5d7541cb886063484f395615