Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tuija M Alcantar"'
Autor:
Arna Katewa, Eric Suto, Jessica Hui, Jose Heredia, Jie Liang, Jason Hackney, Keith Anderson, Tuija M Alcantar, Natasha Bacarro, Debra Dunlap, Jeffrey Eastham, Andres Paler-Martinez, Xin Y Rairdan, Zora Modrusan, Wyne P Lee, Cary D Austin, Daniel Lafkas, Nico Ghilardi
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244439 (2021)
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease representing a serious unmet medical need. The disease is associated with the loss of self-tolerance and exaggerated B cell activation, resulting in autoantibody production and the fo
Externí odkaz:
https://doaj.org/article/ed0d04cf471f47d69accfbf3ee12f167
Autor:
Colin K. Watanabe, Vasantharajan Janakiraman, Michael-Anne Sowick, Jinjie Li, Sobha R. Thamminana, Andrew Buechler, Maximilian Haeussler, Keith R. Anderson, Tuija M. Alcantar, Natasha O’Neil, Linda Ta, Søren Warming, Lucinda Tam, Lisa Lima, Merone Roose-Girma, Steffen Durinck, Jessica Lund, Jeremy Stinson, Charles Yu, Zora Modrusan, Qixin Bei, Xin Y. Rairdan
Publikováno v:
Nature methods, vol 15, iss 7
Despite widespread use of CRISPR, comprehensive data on the frequency and impact of Cas9-mediated off-targets in modified rodents are limited. Here we present deep-sequencing data from 81 genome-editing projects on mouse and rat genomes at 1,423 pred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22389f07059351cf12f2e27d80364c6f
https://doi.org/10.1038/s41592-018-0011-5
https://doi.org/10.1038/s41592-018-0011-5
Publikováno v:
Transgenic Research. 25:527-531
Embryonic stem (ES) cells from a C57BL/6N (B6N) background injected into B6(Cg)-Tyrc-2J/J (B6-albino) recipient blastocysts are commonly used for generating genetically modified mouse models. To understand the influence of the recipient blastocyst st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4782749bab2f408bb3e427c56398fe1
https://doi.org/10.1007/s11248-016-9937-5
https://doi.org/10.1007/s11248-016-9937-5
Autor:
Tuija M, Alcantar, Xin Y, Rairdan
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1874
Since the first knockout rat model was generated with zinc-finger nucleases (ZFNs) by Geurt's group in 2009, the demand for making targeted rat models has increased tremendously. The advent of the clustered regularly interspaced short palindromic rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ab32bb8294c8b86bdb763ac575b96cb
https://pubmed.ncbi.nlm.nih.gov/30353520
https://pubmed.ncbi.nlm.nih.gov/30353520