Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Tuhin K Roy"'
Autor:
Tuhin K Roy, Timothy W. Secomb
Publikováno v:
Frontiers in Physiology, Vol 5 (2014)
A mathematical simulation of flow regulation in vascular networks is used to investigate the interaction between arteriolar vasoconstriction due to sympathetic nerve activity (SNA) and vasodilation due to increased oxygen demand. A network with thirt
Externí odkaz:
https://doaj.org/article/37ef101238514525bf238df426593021
Publikováno v:
Physiological Reports, Vol 11, Iss 17, Pp n/a-n/a (2023)
Abstract Oxygen transport from the lungs to peripheral tissue is dependent on the affinity of hemoglobin for oxygen. Recent experimental data have suggested that the maximum human capacity for oxygen uptake and utilization (V̇O2max) at sea level and
Externí odkaz:
https://doaj.org/article/0d0c9a91442342c48776a27d695f796b
Autor:
Wyatt W. Pruter, Stephen A. Klassen, Paolo B. Dominelli, Chad C. Wiggins, Jonathon W. Senefeld, Tuhin K. Roy, Michael J. Joyner, Sarah E. Baker
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 324:R625-R634
During hypoxic exposure, humans with high-affinity hemoglobin (and compensatory polycythemia) have blunted increases in heart rate compared with healthy humans with typical oxyhemoglobin dissociation curves. This response may be associated with alter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7b739a9c525be77e7e186ce45489d37
https://doi.org/10.1152/ajpregu.00113.2022
https://doi.org/10.1152/ajpregu.00113.2022
Autor:
Timothy W. Secomb, Chad C. Wiggins, Michael J. Joyner, Tuhin K. Roy, Paolo B. Dominelli, Timothy B. Curry
Publikováno v:
Mayo Clin Proc
The oxygen transport cascade describes the physiological ‘steps’ that bring atmospheric oxygen into the body where it is delivered and consumed by metabolically active tissue. As such, the oxygen cascade is fundamental to our understanding of exe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14cfcf7051dddb27643a661c17b87d28
https://doi.org/10.1016/j.mayocp.2020.06.063
https://doi.org/10.1016/j.mayocp.2020.06.063
Autor:
Tuhin K. Roy, Timothy W. Secomb
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ffee6e321b4b38dfa2b2bf69965ddf5
https://doi.org/10.1096/fasebj.2022.36.s1.r6328
https://doi.org/10.1096/fasebj.2022.36.s1.r6328
Autor:
Wyatt W. Pruter, Stephen A. Klassen, Paolo B. Dominelli, Chad C. Wiggins, Jonathon W. Senefeld, Tuhin K. Roy, Michael J. Joyner, Sarah E. Baker
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e86946168e99c6cff4987f3c3c469a8c
https://doi.org/10.1096/fasebj.2022.36.s1.0r874
https://doi.org/10.1096/fasebj.2022.36.s1.0r874
Autor:
Tuhin K Roy, Timothy Secomb
Publikováno v:
Physiological Reports. 10
In the vascular system, an extensive network structure provides convective and diffusive transport of oxygen to tissue. In the microcirculation, parameters describing network structure, blood flow, and oxygen transport are highly heterogeneous. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18210626ddd81e4cc6a60b316be97552
https://doi.org/10.14814/phy2.15303
https://doi.org/10.14814/phy2.15303
Autor:
Paolo B. Dominelli, James D. Hoyer, Shelly K. Roberts, Michael J. Joyner, Sarah E. Baker, Tuhin K. Roy, Jennifer L. Oliveira, John R. A. Shepherd, Chad C. Wiggins, Timothy B. Curry
Publikováno v:
The Journal of Physiology. 598:1475-1490
KEY POINTS Theoretical models suggest there is no benefit of high affinity haemoglobin to preserve maximal oxygen uptake in acute hypoxia but the comparative biology literature has many examples of species that are evolutionarily adapted to hypoxia a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3320d5051bab028c2842234f8d63bcb2
https://doi.org/10.1113/jp279161
https://doi.org/10.1113/jp279161
Autor:
Kevin L. Webb, Ahmed N. Elshaer, Paolo B. Dominelli, Jonathon W. Senefeld, Shane M. Hammer, Sarah E. Baker, John R. A. Shepherd, Tuhin K. Roy, Michael J. Joyner, Chad C. Wiggins
Publikováno v:
Experimental physiology. 107(8)
What is the central question of this study? Do humans with high-affinity haemoglobin (HAH) demonstrate attenuated skeletal muscle deoxygenation during normoxic and hypoxic exercise? What is the main finding and its importance? Examination of near-inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a992d79ec03e71f0afac83652b6c877d
https://pubmed.ncbi.nlm.nih.gov/35603981
https://pubmed.ncbi.nlm.nih.gov/35603981
Autor:
Chad C. Wiggins, John R. A. Shepherd, Paolo B. Dominelli, Jennifer L. Oliveira, Pavol Sajgalik, James D. Hoyer, Glenn M. Stewart, Shelly K. Roberts, Glen E. Foster, Timothy B. Curry, Sarah E. Baker, Tuhin K. Roy, Michael J. Joyner
Publikováno v:
J Appl Physiol (1985)
Arterial oxygen tension and oxyhemoglobin saturation ([Formula: see text]) decrease in parallel during hypoxia. Distinguishing between changes in oxygen tension and oxygen content as the relevant physiological stimulus for cardiorespiratory alteratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::babe795cee31cb1446e45d92ac7e5148
https://doi.org/10.1152/japplphysiol.00569.2019
https://doi.org/10.1152/japplphysiol.00569.2019