Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Tugsan Tezil"'
Autor:
Birgitta Lindqvist, Bianca B Jütte, Luca Love, Wlaa Assi, Julie Roux, Anders Sönnerborg, Tugsan Tezil, Eric Verdin, J Peter Svensson
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010555 (2022)
The reservoir of latently HIV-1 infected cells is heterogeneous. To achieve an HIV-1 cure, the reservoir of activatable proviruses must be eliminated while permanently silenced proviruses may be tolerated. We have developed a method to assess the pro
Externí odkaz:
https://doaj.org/article/847c9d901d944927a0483f2129e6651e
Autor:
Tugsan Tezil, Manish Chamoli, Che-Ping Ng, Roman P. Simon, Victoria J. Butler, Manfred Jung, Julie Andersen, Aimee W. Kao, Eric Verdin
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 5, Iss 1, Pp 1-11 (2019)
Abstract Aging is characterized by the progressive loss of physiological function in all organisms. Remarkably, the aging process can be modulated by environmental modifications, including diet and small molecules. The natural compound nordihydroguai
Externí odkaz:
https://doaj.org/article/fedb936c93fd4ed4a2abe901304bf02a
Autor:
Marius Walter, Ireneusz Habrylo, Kyle A. Raymond, Satish K. Pillai, Melanie Ott, Tugsan Tezil, Steven G. Deeks, Daniela Boehm, Philip A. Hull, Irene P. Chen, Albert Vallejo-Gracia, Andrew Cruz, Emilie Besnard, Karsten Krey, Eric Verdin, Rosalba Perrone, Emilie Battivelli
Publikováno v:
Nature microbiology
Nature microbiology, vol 5, iss 9
Nature microbiology, vol 5, iss 9
Quiescence is a hallmark of CD4+ T cells latently infected with human immunodeficiency virus 1 (HIV-1). While reversing this quiescence is an effective approach to reactivate latent HIV from T cells in culture, it can cause deleterious cytokine dysre
Autor:
J. Peter Svensson, Bianca B. Jütte, Anders Sönnerborg, Birgitta Lindqvist, Luca Love, Eric Verdin, Tugsan Tezil, Julie Roux, Wlaa Assi
The reservoir of latently HIV-1 infected cells is heterogeneous. To achieve an HIV-1 cure, the reservoir of activatable proviruses should be eliminated while permanently silenced proviruses may be tolerated. We have developed a method to assess the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35c5cb0508f4d5d93ba816c4ef71d864
https://doi.org/10.1101/2021.10.04.461021
https://doi.org/10.1101/2021.10.04.461021
Autor:
Martina Lepore Signorile, Rosanna Bagnulo, Giovanna Forte, Paola Sanese, Alessia Peserico, Daria Carmela Loconte, Rosaura Lovaglio, Francesco Susca, Nicoletta Resta, Cristiano Simone, Tugsan Tezil, Valentina Grossi, Candida Fasano
Publikováno v:
Nucleic Acids Research
The HSF and FOXO families of transcription factors play evolutionarily conserved roles in stress resistance and lifespan. In humans, the rs2802292 G-allele at FOXO3 locus has been associated with longevity in all human populations tested; moreover, i
Autor:
Aimee W. Kao, Manfred Jung, Julie K. Andersen, Manish Chamoli, Tugsan Tezil, Eric Verdin, Victoria J. Butler, Che-Ping Ng, Roman P. Simon
Publikováno v:
NPJ aging and mechanisms of disease, vol 5, iss 1
NPJ Aging and Mechanisms of Disease
npj Aging and Mechanisms of Disease, Vol 5, Iss 1, Pp 1-11 (2019)
NPJ Aging and Mechanisms of Disease
npj Aging and Mechanisms of Disease, Vol 5, Iss 1, Pp 1-11 (2019)
Aging is characterized by the progressive loss of physiological function in all organisms. Remarkably, the aging process can be modulated by environmental modifications, including diet and small molecules. The natural compound nordihydroguaiaretic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac3819bb0a4a124767e17062950e6c0
https://doi.org/10.1101/718833
https://doi.org/10.1101/718833
Autor:
Enrico Garattini, Valentina Celestini, Tiziana Cocco, Domenico De Rasmo, L. Russo, Natasha Scialpi, Cristiano Simone, Gaetano Villani, Martina Lepore Signorile, Raffaella Maria Gadaleta, Mineko Terao, Giovanna Forte, Paola Sanese, Anna Signorile, Antonio Moschetta, Valentina Grossi, Alessia Peserico, Giovanna Longo, Candida Fasano, Tugsan Tezil
Publikováno v:
Cell death and disease 9 (2018). doi:10.1038/s41419-018-0336-0
info:cnr-pdr/source/autori:Valentina Celestini, Tugsan Tezil, Luciana Russo, Candida Fasano, Paola Sanese, Giovanna Forte, Alessia Peserico, Martina Lepore Signorile, Giovanna Longo, Domenico De Rasmo, Anna Signorile, Raffaella Maria Gadaleta, Natasha Scialpi, Mineko Terao, Enrico Garattini, Tiziana Cocco, Gaetano Villani, Antonio Moschetta, Valentina Grossi & Cristiano Simone/titolo:Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy/doi:10.1038%2Fs41419-018-0336-0/rivista:Cell death and disease/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Cell Death and Disease, Vol 9, Iss 2, Pp 1-20 (2018)
Cell Death & Disease
info:cnr-pdr/source/autori:Valentina Celestini, Tugsan Tezil, Luciana Russo, Candida Fasano, Paola Sanese, Giovanna Forte, Alessia Peserico, Martina Lepore Signorile, Giovanna Longo, Domenico De Rasmo, Anna Signorile, Raffaella Maria Gadaleta, Natasha Scialpi, Mineko Terao, Enrico Garattini, Tiziana Cocco, Gaetano Villani, Antonio Moschetta, Valentina Grossi & Cristiano Simone/titolo:Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy/doi:10.1038%2Fs41419-018-0336-0/rivista:Cell death and disease/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Cell Death and Disease, Vol 9, Iss 2, Pp 1-20 (2018)
Cell Death & Disease
While aberrant cancer cell growth is frequently associated with altered biochemical metabolism, normal mitochondrial functions are usually preserved and necessary for full malignant transformation. The transcription factor FoxO3A is a key determinant
Autor:
Andrew J. Worth, Jonathan H. Shrimp, Jordan L. Meier, Nathaniel W. Snyder, Eric Verdin, Tugsan Tezil, Alex W Sorum, Julie M. Garlick, Ian A. Blair
Publikováno v:
Molecular pharmaceutics. 15(3)
Non-steroidal anti-inflammatory drugs (NSAIDs) are well known for their effects on inflammatory gene expression. Although NSAIDs are known to impact multiple cellular signaling mechanisms, a recent finding is that the NSAID salicylate can disrupt his
Publikováno v:
Molecular Carcinogenesis. 55:1584-1597
Most tumors primarily rely on glycolysis rather than mitochondrial respiration for ATP production. This phenomenon, also known as Warburg effect, renders tumors more sensitive to glycolytic disturbances compared to normal cells. 3-bromopyruvate is a
Aging causes a gradual decline in normal physiological functions and represents a significant risk factor for several key diseases. Key environmental factors, including diet, play an important role along with genetic factors in determining lifespan.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082c141fc4368691b3f1651759048f42
https://europepmc.org/articles/PMC6183956/
https://europepmc.org/articles/PMC6183956/