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Synthesis of novel 6-(4-substituted piperazine-1-yl)-9-(β-d- ribofuranosyl)purine derivatives, which lead to senescence-induced cell death in liver cancer cells

Autor: Tugce Onder, Ebru Bilget Guven, Meral Tuncbilek, Rengul Cetin Atalay

Publikováno v: Journal of Medicinal Chemistry

Novel purine ribonucleoside analogues (9-13) containing a 4-substituted piperazine in the substituent at N 6 were synthesized and evaluated for their cytotoxicity on Huh7, HepG2, FOCUS, Mahlavu liver, MCF7 breast, and HCT116 colon carcinoma cell line

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b467aec04ea2255d2052b2b228b0114e
https://hdl.handle.net/11693/21506

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