Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tugce Akcan"'
Autor:
Jared Carlson-Stevermer, Amritava Das, Amr A. Abdeen, David Fiflis, Benjamin I Grindel, Shivani Saxena, Tugce Akcan, Tausif Alam, Heidi Kletzien, Lucille Kohlenberg, Madelyn Goedland, Micah J. Dombroe, Krishanu Saha
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Gene correction of multiple alleles is a promising therapeutic strategy. Here the authors present bi-allelic correction of Pompe disease and provide an in silico model for predicting in vivo somatic editing outcomes.
Externí odkaz:
https://doaj.org/article/9ea7446371264a6ca5170a5851e05415
Autor:
Hugo Lee, Rachel J. Fenske, Tugce Akcan, Elliot Domask, Dawn B. Davis, Michelle E. Kimple, Feyza Engin
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101324- (2020)
Summary: The orosomucoid-like (Ormdl) proteins play a critical role in sphingolipid homeostasis, inflammation, and ER stress, all of which are associated with obesity and βcell dysfunction. However, their roles in β cells and obesity remain unknown
Externí odkaz:
https://doaj.org/article/e4129b60719e479c8bf64f74152ff202
Publikováno v:
Journal of the Endocrine Society. 6:A282-A283
Type 1 Diabetes Mellitus (T1DM) results from the autoimmune destruction of insulin-producing pancreatic β cells. Despite advances in our understanding of the pathogenesis and management of diabetes, as well as treatment options, which primarily incl
Publikováno v:
Journal of the Endocrine Society. 6:A566-A567
Introduction While diabetes insipidus rarely presents as a symptom of non-Hodgkin's lymphoma, it is very rarely a revealing symptom of Hodgkin's lymphoma. We present a case of this unique association. Case presentation We report a case of a 25-year-o
Publikováno v:
Cureus.
Autor:
Junting Liu, Tugce Akcan, Rachel Gabor, Brooke Delgoffe, Shivy Sharma, Balwinder Singh, Ajay K Parsaik
Publikováno v:
Journal of the Endocrine Society. 6:A750-A750
Background Despite the abundance of literature, the relationship between hypothyroidism and depression is not clearly defined. We conducted this study to investigate the association of thyroid functioning [measured by serum Thyroid Stimulating Hormon
Autor:
Tugce Akcan, Julia Rose R Shariff
Publikováno v:
Journal of the Endocrine Society. 6:A866-A866
Background Beckwith-Wiedemann Syndrome (BWS) is a genetic condition characterized by macrosomia, childhood tumors, and neonatal hypoglycemia and hyperinsulinemia. The cause of this hyperinsulinemic hypoglycemia is unknown, but it is believed to be ca
Autor:
Jared Carlson-Stevemer, Amritava Das, Amr Abdeen, David Fiflis, Benjamin Grindel, Tugce Akcan, Tausif Alam, Heidi Kletzien, Lucille Kohlenberg, Madelyn Goedland, Micah Dombroe, Krishanu Saha
Gene correction of multiple alleles for compound heterozygous recessive or polygenic diseases is a promising therapeutic strategy. However, the targeting of multiple alleles using genome editors in a single cell could lead to mixed genotypes and adve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c1c7a455fae82c05072d86031104ce1
https://doi.org/10.21203/rs.3.rs-90150/v1
https://doi.org/10.21203/rs.3.rs-90150/v1
Publikováno v:
American Journal of Gastroenterology. 116:S677-S677
Autor:
Yücel Arman, Murat Akarsu, Özgür Altun, Şengül Aydin Yoldemir, Tugce Akcan, Tufan Tükek, Mustafa Özcan, Pınar Demir, İlkim Deniz Toprak, Gülden Yürüyen, Eylem Özgün Çil, Ramazan Cakmak, Kerem Kirna
Publikováno v:
İstanbul Tıp Fakültesi Dergisi. :92-97
Amac: Calismamizin amaci; bir yillik sure icerisinde takip ettigimiz tip 2 diyabetik hastalarin tedavi, tetkik ve muayene icin harcanan maliyetlerini ortaya koyup, bu maliyetlerin bir yillik kontrolde ne kadar etkili oldugunu gostermektir. Gerec ve Y