Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tugba H. Altunok"'
Autor:
Sabire Guler, Tugba H. Altunok, Aybike Sarioglu, Berrin Zik, Deniz Asmaz, Nuray Kayapunar, Oner Sonmez, Burcu Erbaykent Tepedelen, Abdullah Yalcin
Publikováno v:
Biochemical and Biophysical Research Communications. 606:35-41
Transforming growth factor-beta (TGFβ) proteins induce an epithelial-mesenchymal transition (EMT) programme that is associated with increased invasive and drug-resistant phenotype of carcinoma cells. In addition to the canonical pathway involving SM
Autor:
Paul M Campbell, Aydan Mutlu, Tugba H. Altunok, Robertino J. Muchut, Alberto A. Iglesias, Aybike Sarioglu, Abdullah Yalcin, Yunus Gurpinar, Serap Celikler, Selahattin C. Ozcan, Sabire Guler
Publikováno v:
Biochemical and biophysical research communications. 571
Activating mutations of the oncogenic KRAS in pancreatic ductal adenocarcinoma (PDAC) are associated with an aberrant metabolic phenotype that may be therapeutically exploited. Increased glutamine utilization via glutaminase-1 (GLS1) is one such feat
Autor:
Ahmet Akkoç, Selahattin C. Ozcan, Sabire Guler, Saime Güzel, Robertino J. Muchut, Yunus Gurpinar, Tugba H. Altunok, Abdullah Yalcin, Aybike Sarioglu, Alberto A. Iglesias, Yoannis Imbert-Fernandez, Amy L. Clem, Jason Chesney
Publikováno v:
Molecular and cellular biochemistry. 470(1-2)
Tumor cells increase glucose metabolism through glycolysis and pentose phosphate pathways to meet the bioenergetic and biosynthetic demands of rapid cell proliferation. The family of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFKFB1-4) ar