Výsledky vyhledávání - "Tufail, Syed"

Glucose intake induces an increase in activator protein 1 and early growth response 1 binding activities, in the expression of tissue factor and matrix metalloproteinase in mononuclear cells, and in plasma tissue factor and matrix metalloproteinase concentrations

Autor: Paresh Dandona, Tufail Syed, Arindam Bandyopadhyay, Priya Mohanty, Husam Ghanim, Ahmad Aljada

Publikováno v: The American Journal of Clinical Nutrition. 80:51-57

Background: Glucose intake has been shown to cause an increase in intranuclear nuclear factor-B and a decrease in inhibitor B that are consistent with a proinflammatory effect. We investigated the effect of glucose intake on 2 other proinflammatory t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ba2faa26c466f06eff08a5f2c2d292
https://doi.org/10.1093/ajcn/80.1.51

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Differential effects of glucose and alcohol on reactive oxygen species generation and intranuclear nuclear factor-κB in mononuclear cells

Autor: Paresh Dandona, Sandeep Dhindsa, Tufail Syed, Husam Ghanim, Ahmad Aljada, Devjit Tripathy, Priya Mohanty

Publikováno v: Metabolism. 53:330-334

It has previously been shown that oral intake of 300 calories of glucose (75 g), lipid, or protein increases reactive oxygen species (ROS) generation by polymorphonuclear cells (PMNL) and mononuclear cells (MNCs). We investigated the effects of 75 g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b01222602ae7a236b07fd36a030627
https://doi.org/10.1016/j.metabol.2003.10.013

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Angiotensin II Receptor Blocker Valsartan Suppresses Reactive Oxygen Species Generation in Leukocytes, Nuclear Factor-κB, in Mononuclear Cells of Normal Subjects: Evidence of an Antiinflammatory Action

Autor: Rajesh Garg, Husam Ghanim, Ahmad Aljada, Priya Mohanty, Debborah Hofmayer, Vikramjeet Kumar, Tufail Syed, Paresh Dandona, Devjit Tripathy

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 88:4496-4501

In view of the pro-oxidant and proinflammatory effects of angiotensin II, we have tested the hypothesis that valsartan, an angiotensin receptor blocker, may exert a suppressive action on reactive oxygen species (ROS) generation, nuclear factor kappa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e57a7e2c72e2aa2ac393cc5d77da3abb
https://doi.org/10.1210/jc.2002-021836

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Hypogonadotropic Hypogonadism in Erectile Dysfunction Associated with Type 2 Diabetes Mellitus: A Common Defect?

Autor: Tufail Syed, Devjit Tripathy, Assad Khaishagi, Rajesh Garg, Paresh Dandona, Sandeep Dhindsa

Publikováno v: Metabolic Syndrome and Related Disorders. 1:75-80

The objective of this study was to evaluate the gonadal function in men with type 2 diabetes with erectile dysfunction.We examine records of 50 patients with type 2 diabetes and erectile dysfunction who had low free testosterone concentrations. All p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f3a2425cfa621f0344b05110d4536d
https://doi.org/10.1089/154041903321648270

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Circulating mononuclear cells in the obese are in a proinflammatory state

Autor: Tufail Syed, Deborah Hofmeyer, Priya Mohanty, Husam Ghanim, Ahmad Aljada, Paresh Dandona

Publikováno v: Circulation. 110(12)

Background— In view of the increase in plasma concentrations of proinflammatory mediators tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and C-reactive protein (CRP) in obesity, we investigated whether peripheral blood mononuclear cells (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa7999f4aa41cb5a56ee419585d4041
https://pubmed.ncbi.nlm.nih.gov/15364812

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Evidence for a potent antiinflammatory effect of rosiglitazone

Autor: Waddah Al-Haddad, Deborah Hofmeyer, Priya Mohanty, Tufail Syed, Devjit Tripathy, Paresh Dandona, Sandeep Dhindsa, Husam Ghanim, Ahmad Aljada

Publikováno v: The Journal of clinical endocrinology and metabolism. 89(6)

We have recently demonstrated a potent antiinflammatory effect of troglitazone, an agonist of peroxisome proliferator-activated receptor gamma (PPARgamma) and a partial agonist of PPARalpha in both the nondiabetic obese and diabetic obese subjects. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0165e5040a8c30f6347002622c83c82
https://pubmed.ncbi.nlm.nih.gov/15181049

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Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects

Autor: Husam Ghanim, Ahmad Aljada, Priya Mohanty, Tufail Syed, Paresh Dandona, Sandeep Dhindsa, Devjit Tripathy

Publikováno v: Diabetes. 52(12)

To test the possible acute proinflammatory effects of fatty acids, we induced an increase in plasma free fatty acid (FFA) concentrations after a lipid and heparin infusion for 4 h in 10 healthy subjects. We determined the nuclear factor-κB (NF-κB)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa1b83aab2f5260c41ba684d5eee7f7
https://pubmed.ncbi.nlm.nih.gov/14633847

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