Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS

Autor: Wu, Xue, Niculite, Cristina M., Bogdan Preda, Mihai, Rossi, Annalisa, Tebaldi, Toma, Butoi, Elena, White, Mattie K., Tudoran, Oana M., Petrusca, Daniela N., Jannasch, Amber S., Bone, William P., Zong, Xingyue, Fang, Fang, Burlacu, Alexandrina, Paulsen, Michelle T., Hancock, Brad A., Sandusky, George E., Mitra, Sumegha, Fishel, Melissa L., Buechlein, Aaron, Ivan, Cristina, Oikonomopoulos, Spyros, Gorospe, Myriam, Mosley, Amber, Radovich, Milan, Ragoussis, Jiannis, Nephew, Kenneth P., Mari, Bernard, McIntyre, Alan, Konig, Heiko, Ljungman, Mats, Cousminer, Diana L., Macchi, Paolo, Ivan, Mircea

We hereby provide the initial portrait of lincNORS, a spliced lincRNA generated by the MIR193BHG locus, entirely distinct from the previously described miR-193b-365a tandem. While inducible by low O2 in a variety of cells and associated with hypoxia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::ad40cf163025588f283d04624db0e1f5

Publisher Correction: Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS.

Autor: Wu, Xue, Niculite, Cristina M., Preda, Mihai Bogdan, Rossi, Annalisa, Tebaldi, Toma, Butoi, Elena, White, Mattie K., Tudoran, Oana M., Petrusca, Daniela N., Jannasch, Amber S., Bone, William P., Zong, Xingyue, Fang, Fang, Burlacu, Alexandrina, Paulsen, Michelle T., Hancock, Brad A., Sandusky, George E., Mitra, Sumegha, Fishel, Melissa L., Buechlein, Aaron

Publikováno v: Nature Communications; 11/6/2020, Vol. 11 Issue 1, pN.PAG-N.PAG, 1p

Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS.

Autor: Wu X; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Niculite CM; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.; 'Victor Babes' National Institute of Pathology, Bucharest, Romania., Preda MB; Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania., Rossi A; Laboratory of Molecular and Cellular Neurobiology, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento, Italy., Tebaldi T; Laboratory of Translational Genomics, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento, Italy.; Yale Cancer Center, Yale University School of Medicine, New Haven, CT, 06520, USA., Butoi E; Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania., White MK; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Tudoran OM; The Oncology Institute 'Prof Dr. Ion Chiricuta', Cluj-Napoca, Romania., Petrusca DN; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Jannasch AS; Metabolite Profiling Facility, Bindley Bioscience Center, Purdue University, West Lafayette, IN, 47907, USA., Bone WP; Department of Genetics, Department of Systems Pharmacology and Translational Therapeutics, Institute of Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Zong X; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN, USA., Fang F; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN, USA., Burlacu A; Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Bucharest, Romania., Paulsen MT; Departments of Radiation Oncology and Environmental Health Sciences, Center for RNA Biomedicine, University of Michigan, Ann Arbor, MI, 48109, USA., Hancock BA; Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Sandusky GE; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Mitra S; Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, USA.; Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Fishel ML; Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, USA.; Department of Pharmacology and Toxicology, Department of Pediatrics, Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Buechlein A; Indiana University Center for Genomics and Bioinformatics, Bloomington, IN, 47405, USA., Ivan C; Center for RNA Interference and Non-coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Oikonomopoulos S; Department of Human Genetics, McGill University and Genome Quebec Innovation Centre, McGill University, Montréal, QC, Canada., Gorospe M; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD, 21224, USA., Mosley A; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Radovich M; Departments of Radiation Oncology and Environmental Health Sciences, Center for RNA Biomedicine, University of Michigan, Ann Arbor, MI, 48109, USA.; Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, USA., Davé UP; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.; Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, USA., Ragoussis J; Department of Human Genetics, McGill University and Genome Quebec Innovation Centre, McGill University, Montréal, QC, Canada., Nephew KP; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN, USA.; Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, USA.; Medical Sciences, Indiana University School of Medicine, Bloomington, IN, USA., Mari B; CNRS, IPMC, FHU-OncoAge, Université Côte d'Azur, Valbonne, France., McIntyre A; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, 48109, USA., Konig H; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.; Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, USA., Ljungman M; Departments of Radiation Oncology and Environmental Health Sciences, Center for RNA Biomedicine, University of Michigan, Ann Arbor, MI, 48109, USA.; Centre for Cancer Sciences, Biodiscovery Institute, Nottingham University, Nottingham, UK., Cousminer DL; Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Macchi P; Laboratory of Molecular and Cellular Neurobiology, Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Trento, Italy., Ivan M; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. mivan@iu.edu.; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, 46202, USA. mivan@iu.edu.; Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, USA. mivan@iu.edu.

Publikováno v: Nature communications [Nat Commun] 2020 Sep 21; Vol. 11 (1), pp. 4755. Date of Electronic Publication: 2020 Sep 21.