Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Tudor Oprea"'
Autor:
Stella M Bernardo, Christopher P Allen, Anna Waller, Susan M Young, Tudor Oprea, Larry A Sklar, Samuel A Lee
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110354 (2014)
Although three major classes of systemic antifungal agents are clinically available, each is characterized by important limitations. Thus, there has been considerable ongoing effort to develop novel and repurposed agents for the therapy of invasive f
Externí odkaz:
https://doaj.org/article/760d2a3398e9468ba233a01bb72fda69
Autor:
Robert Hromas, Suk-Hee Lee, Jac A. Nickoloff, Wei Wang, Julie Bauman, Montaser Shaheen, Larry Sklar, Tudor Oprea, Helen Hathaway, Chelin Hu, Andrei Leitao, Leah Damiani, Elizabeth A. Williamson
PDF file - 670K, Figure S1. The composite approach for in silico compound selection. Figure S2. Superposition of the 3D structures of Metnase (model, blue) and MOS-1 active sites (2F7T, orange). Figure S3. Comparison between two metnase structures Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4e89566092f2e96619fb74328a9751
https://doi.org/10.1158/0008-5472.22392029
https://doi.org/10.1158/0008-5472.22392029
Autor:
Luca Cappelletti, Lauren Rekerle, Tommaso Fontana, Peter Hansen, Elena Casiraghi, Vida Ravanmehr, Christopher J Mungall, Jeremy Yang, Leonard Spranger, Guy Karlebach, J. Harry Caufield, Leigh Carmody, Ben Coleman, Tudor Oprea, Justin Reese, Giorgio Valentini, Peter N Robinson
Graph representation learning is a family of related approaches that learn low-dimensional vector representations of nodes and other graph elements called embeddings. Embeddings approximate characteristics of the graph and can be used for a variety o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b91f6c80ffe2a5099baac6ccb7091289
https://doi.org/10.1101/2022.11.21.517376
https://doi.org/10.1101/2022.11.21.517376
Autor:
María Paula Magariños, Anna Gaulton, Eloy Félix, Tevfik Kizilören, Ricardo Arcila, Tudor Oprea, Andrew R. Leach
Publikováno v:
PeerJ. 11:e15153
The patent literature is a potentially valuable source of bioactivity data. In this article we describe a process to prioritise 3.7 million life science relevant patents obtained from the SureChEMBL database (https://www.surechembl.org/), according t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0966709e88dfb0dd844bb66573567e82
https://doi.org/10.7717/peerj.15153
https://doi.org/10.7717/peerj.15153
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 36
Since the 1960s viral pathogenesis researchers have considered herpesviruses as an underlying factor for Alzheimer's disease (AD). We reported molecular interactions between herpes simplex virus type 1 (HSV-1) and the amyloid precursor protein (APP),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0713021c76b38d4ba703dd920a5552
https://pubmed.ncbi.nlm.nih.gov/35723876
https://pubmed.ncbi.nlm.nih.gov/35723876
Autor:
Mihai Tudor OPREA
Publikováno v:
Transylvanian Review of Administrative Sciences, Vol 4, Iss 23, Pp 74-89 (2008)
The concern of this paper is urban renewal projects; it investigates how such projects get off the ground. A variety of bodies have examined and devised instruments to tackle the inherent difficulties. “How can cities overcome critical factors in t
Externí odkaz:
https://doaj.org/article/495c97d5f3d34324ac6187841d3141fc
Glucose is an essential energy source for cells. In humans, its passive diffusion through the cell membrane is facilitated by members of the glucose transporter family (GLUT, SLC2 gene family). GLUT2 transports both glucose and fructose with low affi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e6679a2ca17408ee0b5a8575537e662
https://doi.org/10.21203/rs.3.rs-489875/v1
https://doi.org/10.21203/rs.3.rs-489875/v1
Autor:
Jeremy Yang, Dhouha Grissa, Stephen Mathias, Anna Waller, David Wild, Christophe Lambert, Lars Juhl Jensen, Tudor Oprea
Genome-wide association studies (GWAS) generate large volumes of associations between genomic variations and phenotypic traits. However, assessing strength, specificity and relevance of associations, and semantically valid aggregation of associations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947bb43b97efaf3f992457fc6a43a81b
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
Computational toxicology is a new discipline in the area of computational molecular sciences, which is rapidly developing as a result of the public interest stirred by several European and US initiatives. Here, we report the use of primary high throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::db95fa311249484dbb0d4e10506c3297
https://europepmc.org/articles/PMC4557807/
https://europepmc.org/articles/PMC4557807/
Autor:
Gerhard Wolber, Tudor Oprea, Judith Rollinger, Khalil Azzaoui, Antony Williams, María Isabel Loza García, Jean-Louis Reymond, Gisbert Schneider
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fcf810e56567f8d08f533b76ba96697
https://doi.org/10.1201/b15631
https://doi.org/10.1201/b15631