Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Tudor Luchian"'
Autor:
Su Jin Ko, Eunji Park, Alina Asandei, Jee-Young Choi, Seung-Chul Lee, Chang Ho Seo, Tudor Luchian, Yoonkyung Park
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Antimicrobial peptides have attracted attention as alternatives to conventional antibiotics. Previously, a novel antimicrobial peptide, melectin, consisting of 18 amino acids was isolated from the venom of a bee, Melecta albifrons. Here, we
Externí odkaz:
https://doaj.org/article/bcd81e0dfe3d49aa8b83f3167750b21b
Autor:
Ioana C. Bucataru, Isabela Dragomir, Alina Asandei, Ana-Maria Pantazica, Alina Ghionescu, Norica Branza-Nichita, Yoonkyung Park, Tudor Luchian
Publikováno v:
Biosensors, Vol 12, Iss 8, p 596 (2022)
Real-time monitoring, simple operation, and cheaper methods for detecting immunological proteins hold the potential for a solid influence on proteomics and human biology, as they can promote the onset of timely diagnoses and adequate treatment protoc
Externí odkaz:
https://doaj.org/article/73741fa8e4484b7282f902d110f2ffc4
Publikováno v:
AMB Express, Vol 9, Iss 1, Pp 1-15 (2019)
Abstract Rates of microbial drug resistance are increasing worldwide; therefore, antimicrobial peptides (AMPs) are considered promising alternative therapeutic agents to antibiotics. AMPs are essential components of the innate immune system and exhib
Externí odkaz:
https://doaj.org/article/284e715a3c974bcaa10a2b05bb1b1f78
Autor:
Isabela S. Dragomir, Alina Asandei, Irina Schiopu, Ioana C. Bucataru, Loredana Mereuta, Tudor Luchian
Publikováno v:
Polymers, Vol 13, Iss 8, p 1210 (2021)
The implication of nanopores as versatile components in dedicated biosensors, nanoreactors, or miniaturized sequencers has considerably advanced single-molecule investigative science in a wide range of disciplines, ranging from molecular medicine and
Externí odkaz:
https://doaj.org/article/85ec802827c04cb6bd17369e97f12911
Autor:
Alina Asandei, Andrei Ciuca, Aurelia Apetrei, Irina Schiopu, Loredana Mereuta, Chang Ho Seo, Yoonkyung Park, Tudor Luchian
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Herein, we describe at uni-molecular level the interactions between poly(amidoamine) (PAMAM) dendrimers of generation 1 and the α-hemolysin protein nanopore, at acidic and neutral pH, and ionic strengths of 0.5 M and 1 M KCl, via single-mol
Externí odkaz:
https://doaj.org/article/680ddb1ae8bd43b6a3a45424a544db0f
Autor:
Alina Asandei, Isabela S. Dragomir, Giovanni Di Muccio, Mauro Chinappi, Yoonkyung Park, Tudor Luchian
Publikováno v:
Polymers, Vol 10, Iss 8, p 885 (2018)
In this work, we demonstrate the proof-of-concept of real-time discrimination between patches of hydrophilic and hydrophobic monomers in the primary structure of custom-engineered, macro-dipole-like peptides, at uni-molecular level. We employed singl
Externí odkaz:
https://doaj.org/article/978226d8140b437a8a1809c32e28d514
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25276 (2011)
While it is accepted that biomembrane asymmetry is generated by proteins and phospholipids distribution, little is known about how electric changes manifested in a monolayer influence functional properties of proteins localized on the opposite leafle
Externí odkaz:
https://doaj.org/article/653189f5f6e34d2f85fd5313973e5912
Autor:
Loredana Mereuta, Alina Asandei, Isabela Dragomir, Jonggwan Park, Yoonkyung Park, Tudor Luchian
Publikováno v:
Analytical Chemistry. 94:8774-8782
Real-time and easy-to-use detection of nucleic acids is crucial for many applications, including medical diagnostics, genetic screening, forensic science, or monitoring the onset and progression of various diseases. Herein, an exploratory single-mole
Autor:
Cezara Bucataru, Alina Asandei, Isabela S. Dragomir, Loredana Mereuta, Tudor Luchian, Irina Schiopu
Publikováno v:
Studia Universitatis Babeș-Bolyai Chemia. 66:161-174
Publikováno v:
Chemistry, an Asian journal. 17(12)
To alleviate solubility-related shortcomings associated with the use of neutral peptide nucleic acids (PNA), a powerful strategy is incorporate various charged sidechains onto the PNA structure. Here we employ a single-molecule technique and prove th