Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Tudor Constantin Badea"'
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
Sending an axon out of the eye and into the target brain nuclei is the defining feature of retinal ganglion cells (RGCs). The literature on RGC axon pathfinding is vast, but it focuses mostly on decision making events such as midline crossing at the
Externí odkaz:
https://doaj.org/article/d52b121ec34f477c94f191a516959dc4
Autor:
Jen-Zen Chuang, Nan Yang, Nobuyuki Nakajima, Wataru Otsu, Cheng Fu, Howard Hua Yang, Maxwell Ping Lee, Armaan Fazal Akbar, Tudor Constantin Badea, Ziqi Guo, Afnan Nuruzzaman, Kuo-Shun Hsu, Joshua L. Dunaief, Ching-Hwa Sung
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Age-related macular degeneration (AMD) is a leading cause of blindness and is characterised by the accumulation of lipid deposits, called drusen. Here, the authors show that mice lacking chloride intracellular channel 4 in retinal pigment epithelium
Externí odkaz:
https://doaj.org/article/6225ad8d8100460da61f269eb1c4addd
Autor:
Kazuhiko Nishida, Shinji Matsumura, Hitoshi Uchida, Manabu Abe, Kenji Sakimura, Tudor Constantin Badea, Takuya Kobayashi
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0285295 (2023)
The spinal dorsal horn comprises heterogeneous neuronal populations, that interconnect with one another to form neural circuits modulating various types of sensory information. Decades of evidence has revealed that transcription factors expressed in
Externí odkaz:
https://doaj.org/article/c9ce63c4e43146588cd9f32b121ddb26
Publikováno v:
Neural Development, Vol 16, Iss 1, Pp 1-26 (2021)
Abstract Background While the transcriptional code governing retinal ganglion cell (RGC) type specification begins to be understood, its interplay with neurotrophic signaling is largely unexplored. In mice, the transcription factor Brn3a/Pou4f1 is ex
Externí odkaz:
https://doaj.org/article/0f875c0fc8c74d53a5f05fe9d939271e
Autor:
Katherine M. Oliver, Danny M. Florez-Paz, Tudor Constantin Badea, George Z. Mentis, Vilas Menon, Joriene C. de Nooij
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Coordinated movement critically depends on sensory feedback from muscle spindles (MSs) and Golgi tendon organs (GTOs) but the afferents supplying this proprioceptive feedback have remained genetically inseparable. Here the authors use single cell tra
Externí odkaz:
https://doaj.org/article/1a25f8a076bf42029aa7c592d7e11206
Publikováno v:
Neural Development, Vol 13, Iss 1, Pp 1-33 (2018)
Abstract Background About 20–30 distinct Retinal Ganglion Cell (RGC) types transmit visual information from the retina to the brain. The developmental mechanisms by which RGCs are specified are still largely unknown. Brn3a is a member of the Brn3/P
Externí odkaz:
https://doaj.org/article/e7477004bfe945eda95f65aa06b555bd
Autor:
Szilard Sajgo, Miruna Georgiana Ghinia, Melody Shi, Pinghu Liu, Lijin Dong, Nadia Parmhans, Octavian Popescu, Tudor Constantin Badea
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91435 (2014)
BACKGROUND: Genetic targeting methods have greatly advanced our understanding of many of the 20 Retinal Ganglion Cell (RGC) types conveying visual information from the eyes to the brain. However, the complexity and partial overlap of gene expression
Externí odkaz:
https://doaj.org/article/4be277a4b5cb4317b4f2cfbcaa7355eb
Autor:
Alexandru Tatomir, Dallas Boodhoo, Vinh Nguyen, Cornelia Cudrici, Tudor Constantin Badea, Violeta Rus, Horea Rus
Publikováno v:
The Journal of Immunology. 204:64.9-64.9
Astrocytes are increasingly recognized as critical contributors to multiple sclerosis pathogenesis. We have previously shown that lack of response gene to complement 32 (RGC-32) alters astrocyte morphology in spinal cords during experimental autoimmu