Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Tudor C Badea"'
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0255860 (2021)
The molecular mechanisms underlying morphological diversity in retinal cell types are poorly understood. We have previously reported that several members of the Copine family of Ca-dependent membrane adaptors are expressed in Retinal Ganglion Cells a
Externí odkaz:
https://doaj.org/article/6d48dafdd6204749bbc7f50fc0fe0f4d
A visual circuit uses complementary mechanisms to support transient and sustained pupil constriction
Autor:
William Thomas Keenan, Alan C Rupp, Rachel A Ross, Preethi Somasundaram, Suja Hiriyanna, Zhijian Wu, Tudor C Badea, Phyllis R Robinson, Bradford B Lowell, Samer S Hattar
Publikováno v:
eLife, Vol 5 (2016)
Rapid and stable control of pupil size in response to light is critical for vision, but the neural coding mechanisms remain unclear. Here, we investigated the neural basis of pupil control by monitoring pupil size across time while manipulating each
Externí odkaz:
https://doaj.org/article/2270a85585954d368d40f963bb9b4bd0
Genetic interactions between Brn3 transcription factors in retinal ganglion cell type specification.
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76347 (2013)
Visual information is conveyed from the retina to the brain via 15-20 Retinal Ganglion Cell (RGC) types. The developmental mechanisms by which RGC types acquire their distinct molecular, morphological, physiological and circuit properties are essenti
Externí odkaz:
https://doaj.org/article/793ffc7f28244d9eaf751a5c6ce80b50
Autor:
Tudor C Badea, Zhong L Hua, Philip M Smallwood, John Williams, Thomas Rotolo, Xin Ye, Jeremy Nathans
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7859 (2009)
Pharmacologic control of Cre-mediated recombination using tamoxifen-dependent activation of a Cre-estrogen receptor ligand binding domain fusion protein [CreER(T)] is widely used to modify and/or visualize cells in the mouse.We describe here two new
Externí odkaz:
https://doaj.org/article/5f20bdea26e14b5791bcc5c6ef58dcae
Pou4f1-Tbr1 transcriptional cascade controls the formation of Jam2-expressing retinal ganglion cells
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
More than 40 retinal ganglion cell (RGC) subtypes have been categorized in mouse based on their morphologies, functions, and molecular features. Among these diverse subtypes, orientation-selective Jam2-expressing RGCs (J-RGCs) has two unique morpholo
Externí odkaz:
https://doaj.org/article/3f2a81bc56a741e68b422cec34dcfe21
Autor:
Alexandru Tatomir, Austin Beltrand, Vinh Nguyen, Jean-Paul Courneya, Dallas Boodhoo, Cornelia Cudrici, Dafin F. Muresanu, Violeta Rus, Tudor C. Badea, Horea Rus
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Response Gene to Complement 32 (RGC-32) is an important mediator of the TGF-β signaling pathway, and an increasing amount of evidence implicates this protein in regulating astrocyte biology. We showed recently that spinal cord astrocytes in mice lac
Externí odkaz:
https://doaj.org/article/6ab4589ccead47d7b05317a5a92110a0
Autor:
Alexandru Tatomir, Austin Beltrand, Vinh Nguyen, Dallas Boodhoo, Armugam Mekala, Cornelia Cudrici, Tudor C. Badea, Dafin F. Muresanu, Violeta Rus, Horea Rus
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Astrocytes are increasingly recognized as critical contributors to multiple sclerosis pathogenesis. We have previously shown that lack of Response Gene to Complement 32 (RGC-32) alters astrocyte morphology in the spinal cord at the peak of experiment
Externí odkaz:
https://doaj.org/article/d0ac47c8491a434c82051567eb600e28
Autor:
Jean-Paul Courneya, Rita Fishelevich, Irina G. Luzina, Violeta Rus, Sergei P. Atamas, Brian Hampton, Alexander V. Misharin, Nevins W. Todd, Virginia Lockatell, Tudor C. Badea, Horea Rus
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 66:146-157
Some previous studies in tissue fibrosis have suggested a profibrotic contribution from elevated expression of a protein termed either Regulator of Cell Cycle (RGCC) or Response Gene to Complement 32 Protein (RGC-32). Our analysis of public gene expr
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 3, Pp 559-571 (2016)
Site-specific recombinases (SSRs) such as Cre are widely used in gene targeting and genetic approaches for cell labeling and manipulation. They mediate DNA strand exchange between two DNA molecules at dedicated recognition sites. Precise understandin
Externí odkaz:
https://doaj.org/article/fbb0a56ce9794cd4b927d939c9dccc16
Publikováno v:
Frontiers in Immunology. 13
Recent advances in understanding the pathogenesis of multiple sclerosis (MS) have brought into the spotlight the major role played by reactive astrocytes in this condition. Response Gene to Complement (RGC)-32 is a gene induced by complement activati