Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tudor Badea"'
Autor:
John Papadimitriou, Alexandru Tatomir, Vinh Nguyen, Violeta Rus, Tudor Badea, Horea Rus, Cinthia Drachenberg
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/d2436614a32c46fbba72f38e0321fda8
Autor:
Violeta Rus, Alexandru Tatomir, Vinh Nguyen, Ana Talpos-Caia, John Papadimitriou, Sergei Atamas, Irina Luzina, Sun-Sang J Sung, Tudor Badea, Horea Rus
Publikováno v:
The Journal of Immunology. 202:132.3-132.3
Response Gene to Complement (RGC)-32 is a cell cycle regulator induced by complement activation, growth factors and cytokines. RGC-32 mediates TGF-β dependent profibrotic pathways, while in immune cells promotes the differentiation of Th17 cells in
Autor:
Alexandru Tatomir, Dallas Boodhoo, Vinh Nguyen, Cornelia Cudrici, Tudor Badea, Violeta Rus, Horea Rus
Publikováno v:
The Journal of Immunology. 202:52.4-52.4
Response gene to complement (RGC)-32 plays an important role in the mediation of TGF-β downstream effects and activation of cell cycle. During experimental autoimmune encephalomyelitis (EAE), RGC-32 knock-out (KO) mouse astrocytes displayed an elong
Autor:
Teodora Niculescu, Moon L. Shin, Jae-Hyun Park, Lucian Soane, Tudor Badea, Horea Rus, Florin Niculescu
Publikováno v:
Journal of Neuroimmunology. 142:58-66
Sublytic C5b-9 alters the molecular phenotype of myotubes by inhibiting muscle-specific gene expression. Here, we showed that C5b-9 induced c-fos mRNA and transcription. Using c-fos promoter-CAT constructs and electrophoretic mobility shift assay (EM
Autor:
Horea Rus, Cosmin Tegla, Cornelia Cudrici, Vinh Nguyen, Adam Kruszewski, Amurgam Mekala, Violeta Rus, Tudor Badea
Publikováno v:
The Journal of Immunology. 194:129.6-129.6
We have previously shown that RGC-32 is involved in cell cycle regulation in vitro. To define the in vivo role of RGC-32, we generated RGC-32 knockout mice. To assess the effect of RGC-32 deficiency on cell cycle activation in T cells, we determined
Autor:
Violeta Rus, Vinh Nguyen, Tudor Badea, Cornelia Cudrici, Cosmin Tegla, Armugam Mekala, Horea Rus
Publikováno v:
The Journal of Immunology. 194:67.16-67.16
Response Gene to Complement (RGC)-32 is an intracytoplasmatic protein expressed in a variety of cells in response to sublytic complement activation, TGFb and other cytokines. It plays a role in cell growth, fibroblast activation and renal fibrosis, T
Publikováno v:
The Journal of Immunology. 192:64.2-64.2
Our group has cloned and characterized the Response Gene to Complement (RGC)-32 which is induced by C5b-9 and exerts an important role in cell cycle activation via cyclin B1-CDC2 activation and Akt phosphorylation. RGC-32 is also a downstream target
Autor:
Cosmin Tegla, Cornelia Cudrici, Vinh Nguyen, Jacob Danoff, Sonia Vlaicu, Violeta Rus, Tudor Badea, Horea Rus
Publikováno v:
The Journal of Immunology. 190:50.18-50.18
We have previously shown that RGC-32 is involved in cell cycle regulation in vitro. To define the in vivo role of RGC-32, we generated RGC-32 knockout mice. These mice develop normally and do not spontaneously develop overt tumors. To assess the effe
Autor:
Cosmin Tegla, Cornelia Cudrici, Vinh Nguyen, Ali Khan, Sonia Vlaicu, Violeta Rus, Tudor Badea, Horea Rus
Publikováno v:
The Journal of Immunology. 188:115.3-115.3
We have previously identified Response Gene to Complement (RGC)-32 as a factor induced by complement activation, growth factors and cytokines. To study the in vivo function of RGC-32, we have generated mice carrying a null allele of the gene. Mice la
Publikováno v:
Journal of Neuroimmunology. 90:31