Discovery of new molecular hybrid derivatives with coumarin scaffold bearing pyrazole/oxadiazole moieties: Molecular docking, POM analyses, in silico pharmacokinetics and in vitro antimicrobial evaluation with identification of potent antitumor pharmacophore sites.

Autor: Tataringa G; University of Medicine and Pharmacy Grigore T. Popa Iasi, Romania., Tuchilus C; University of Medicine and Pharmacy Grigore T. Popa Iasi, Romania., Ahmed M; Department of Zoology, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Kingdom of Saudi Arabia., Ahmed S; Post-Graduate and Research Department of Chemistry, The New College (Autonomous), University of Madras, Chennai 600 014, India. Electronic address: sumeerchoudhary15@gmail.com., Bhat AR; Department of Chemistry, RTM Nagpur University, Nagpur 440 033, India. Electronic address: bhatajmal@gmail.com., Ben Hadda T; Euromed Research Center, Euromed Faculty of Pharmacy and School of Engineering in Biomedical and Biotechnology, Euromed University of Fes (UEMF), Meknes Road, Fez 30000, Morocco., Zbancioc AM; University of Medicine and Pharmacy Grigore T. Popa Iasi, Romania. Electronic address: ana.zbancioc@umfiasi.ro., Fahelelbom KM; Department of Pharmaceutical Science, College of Pharmacy, Al Ain University, Al Ain, United Arab Emirates.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2024 Aug 30; Vol. 153, pp. 107761. Date of Electronic Publication: 2024 Aug 30.

The role of RANKL and FGF23 in Assessing Bone Turnover in Type 2 Diabetic Patients

Autor: Mariana Graur, Tuchilus C, Laura Mihalache, Herghelegiu Am, Otilia Niță, Lidia Iuliana Arhire, Andreea Gherasim, Niță G

Publikováno v: Acta Endocrinol (Buchar)

CONTEXT. Type 2 diabetes is a chronic metabolic disease which affects bone. There is evidence in the literature about some serum markers that reflect the bone turnover metabolism, such as RANKL (Receptor Activator of Nuclear factor Kappa-b Ligand) an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::552a758ed5844c0506d6527a584b577c
https://europepmc.org/articles/PMC8417483/

ECG and Biomarker Profile in Patients with Acute Heart Failure: A Pilot Study.

Autor: Chetran A; Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.; Cardiology Clinic, Clinical Emergency Hospital 'Sfantul Spiridon', 700111 Iasi, Romania., Costache AD; Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.; Department of Cardiovascular Rehabilitation, Clinical Rehabilitation Hospital, 700661 Iasi, Romania., Ciongradi CI; 2nd Department of Surgery-Pediatric Surgery and Orthopedics, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iași, Romania.; Pediatric and Orthopaedic Surgery Clinic, 'Sfânta Maria' Emergency Children Hospital, 700309 Iași, Romania., Duca ST; Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.; Cardiology Clinic, Clinical Emergency Hospital 'Sfantul Spiridon', 700111 Iasi, Romania., Mitu O; Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.; Cardiology Clinic, Clinical Emergency Hospital 'Sfantul Spiridon', 700111 Iasi, Romania., Sorodoc V; Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.; II Internal Medicine Clinic, Clinical Emergency Hospital 'Sfantul Spiridon', 700111 Iasi, Romania., Cianga CM; Department of Immunology, Faculty of Medicine, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.; Immunology Laboratory, Clinical Emergency Hospital 'Sfantul Spiridon', 700111 Iasi, Romania., Tuchilus C; Department of Microbiology, Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.; Microbiology Laboratory, Clinical Emergency Hospital 'Sfantul Spiridon', 700111 Iasi, Romania., Mitu I; Department of Morpho-Functional Sciences II, Faculty of Medicine, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania., Mitea RD; Department of Cardiology, Faculty of Medicine, University of Medicine and Pharmacy 'Lucian Blaga, 550169 Sibiu, Romania.; Cardiology Clinic, Clinical Emergency Hospital Sibiu, 550245 Sibiu, Romania., Badescu MC; Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.; III Internal Medicine Clinic, Clinical Emergency Hospital 'Sfantul Spiridon', 700111 Iasi, Romania., Afrasanie I; Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.; Cardiology Clinic, Clinical Emergency Hospital 'Sfantul Spiridon', 700111 Iasi, Romania., Huzum B; Department of Physiology, Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.; Department of Orthopaedics and Traumatology, 'Sf. Spiridon' Emergency County Hospital, 700111 Iasi, Romania., Moisa SM; Department of Pediatrics, Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania., Prepeliuc CS; 'Saint Parascheva', Infectious Diseases Clinical Universitary Hospital Iasi, 700116 Iasi, Romania., Roca M; Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.; Department of Cardiovascular Rehabilitation, Clinical Rehabilitation Hospital, 700661 Iasi, Romania., Costache II; Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy 'Gr. T. Popa', 700115 Iasi, Romania.; Cardiology Clinic, Clinical Emergency Hospital 'Sfantul Spiridon', 700111 Iasi, Romania.

Publikováno v: Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2022 Dec 03; Vol. 12 (12). Date of Electronic Publication: 2022 Dec 03.

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A six-mounth evaluation of inflammatory biomarkers prognostic predictability in patients with peripheral artery disease.

Autor: Ceasovschih, A., Sorodoc, V., Onofrei, V., Tesloianu, D., Petris, A.O., Tuchilus, C., Jaba, E., Lionte, C., Statescu, C., Stoica, A., Haliga, R.E., Dumitrescu, G., Sirbu, O., Vata, L.G., Petris, O.R., Bologa, C., Constantin, M., Grigorescu, D.E., Alexa, R.E., Barcan, S., Jaba, I.M., Sorodoc, L.

Publikováno v: In Atherosclerosis August 2021 331:e232-e232