The centriolar satellite protein Cfap53 facilitates formation of the zygotic microtubule organizing center in the zebrafish embryo

Autor: Willekers, Sven, Tessadori, Federico, van der Vaart, Babet, Henning, Heiko H., Stucchi, Riccardo, Altelaar, Maarten, Roelen, Bernard A.J., Akhmanova, Anna, Bakkers, Jeroen, Sub Cell Biology, Voortplanting paard, Afd Biomol.Mass Spect. and Proteomics, Anatomie en fysiologie, Celbiologie, Al het onderzoek van de faculteit Diergeneeskunde, CS_Cancer

Publikováno v: Development (Cambridge, England), 149(16), 1. Company of Biologists Ltd
Development (Cambridge), 149(16). Company of Biologists Ltd

In embryos of most animal species, the zygotic centrosome is assembled by the centriole derived from the sperm cell and pericentriolar proteins present in the oocyte. This zygotic centrosome acts as a microtubule organizing center (MTOC) to assemble

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9201a33b12009a9e3c67971c904e84a8
https://doi.org/10.1242/dev.198762

Autophagy mediates the clearance of oligodendroglial SNCA/alpha-synuclein and TPPP/p25A in multiple system atrophy models

Autor: Mavroeidi, Panagiota, Arvanitaki, Fedra, Vetsi, Maria, Becker, Stefan, Vlachakis, Dimitrios, Jensen, Poul Henning, Stefanis, Leonidas, Xilouri, Maria

Publikováno v: Mavroeidi, P, Arvanitaki, F, Vetsi, M, Becker, S, Vlachakis, D, Jensen, P H, Stefanis, L & Xilouri, M 2022, ' Autophagy mediates the clearance of oligodendroglial SNCA/alpha-synuclein and TPPP/p25A in multiple system atrophy models ', Autophagy, vol. 18, no. 9, pp. 2104-2133 . https://doi.org/10.1080/15548627.2021.2016256
Autophagy

Accumulation of the neuronal protein SNCA/alpha-synuclein and of the oligodendroglial phosphoprotein TPPP/p25A within the glial cytoplasmic inclusions (GCIs) represents the key histophathological hallmark of multiple system atrophy (MSA). Even though

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73df00d509ef0d8891a89cfe35e4fd89

Quantitative mapping of dense microtubule arrays in mammalian neurons

Autor: Katrukha, Eugene A, Jurriens, Daphne, Salas Pastene, Desiree M, Kapitein, Lukas C, Sub Cell Biology, Celbiologie

Publikováno v: eLife, 10, 1. eLife Sciences Publications
elife
eLife, Vol 10 (2021)
eLife

The neuronal microtubule cytoskeleton underlies the polarization and proper functioning of neurons, amongst others by providing tracks for motor proteins that drive intracellular transport. Different subsets of neuronal microtubules, varying in compo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6163981e83876b16d85d1db7b2c5c941
https://dspace.library.uu.nl/handle/1874/419552

Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy

Autor: Diederik W. D. Kuster, Maike Schuldt, Saskia Schlossarek, Jaco C. Knol, Thang V. Pham, Michiel Dalinghaus, Michelle Michels, Tim Schelfhorst, Connie R. Jimenez, Marie-Jo Moutin, Jolanda van der Velden, Sander R. Piersma, Jiayi Pei, Michal Mokry, Larissa M. Dorsch, Lucie Carrier, Magdalena Harakalova, Cris dos Remedios, Folkert W. Asselbergs

Publikováno v: Circulation. Heart failure
Circulation. Heart failure, 2021, 14 (1), ⟨10.1161/CIRCHEARTFAILURE.120.007022⟩
Circulation. Heart failure, 14(1):e007022. Lippincott Williams & Wilkins
Circulation. Heart Failure
Circ Heart Fail
Circulation. Heart failure, 14(1). Lippincott Williams and Wilkins
Schuldt, M, Pei, J, Harakalova, M, Dorsch, L M, Schlossarek, S, Mokry, M, Knol, J C, Pham, T V, Schelfhorst, T, Piersma, S R, Dos Remedios, C, Dalinghaus, M, Michels, M, Asselbergs, F W, Moutin, M-J, Carrier, L, Jimenez, C R, van der Velden, J & Kuster, D W D 2021, ' Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy ', Circulation. Heart failure, vol. 14, no. 1, e007022 . https://doi.org/10.1161/CIRCHEARTFAILURE.120.007022
Circulation. Heart failure, Lippincott Williams & Wilkins, 2021, 14 (1), ⟨10.1161/CIRCHEARTFAILURE.120.007022⟩
Circulation. Heart failure, 14(1):e007022. Lippincott Williams and Wilkins

Supplemental Digital Content is available in the text.
Background: Hypertrophic cardiomyopathy (HCM) is the most common genetic heart disease. While ≈50% of patients with HCM carry a sarcomere gene mutation (sarcomere mutation-positive, HCMSMP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536db8cc06d783840bdc2eb32fe1bbfe
https://doi.org/10.1161/circheartfailure.120.007022

Vitellogenin expression in the oilseed rape pest Meligethes aeneus

Autor: Michael Kristensen, Caroline Kaiser, Christina Lazaridou, Karl-Martin Vagn Jensen, Rodrigo Labouriau

Publikováno v: Kaiser, C, Lazaridou, C, Jensen, K-M V, Labouriau, R & Kristensen, M 2019, ' Vitellogenin expression in the oilseed rape pest Meligethes aeneus ', Insect Science, vol. 26, no. 2, pp. 274-282 . https://doi.org/10.1111/1744-7917.12539

When investigating insecticide resistance of pest insects, for example, the pollen beetle Meligethes aeneus, it is relevant to differentiate toxicological and molecular genetic data between male and female specimens. A molecular sex determination met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6fb69f527dbfe2a3b846b574db3bb4
https://pure.au.dk/portal/da/publications/vitellogenin-expression-in-the-oilseed-rape-pest-meligethes-aeneus(5f79fcb7-22e4-4f8e-90b0-940a0ef13a14).html