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Genetic architecture and socio-environmental risk factors for major depressive disorder in Nepal.

Autor: Choi KW; Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute, Boston, MA, USA., Tubbs JD; Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute, Boston, MA, USA., Lee YH; Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute, Boston, MA, USA., He Y; Stanley Center for Psychiatric Research, Broad Institute, Boston, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Tsuo K; Stanley Center for Psychiatric Research, Broad Institute, Boston, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Yohannes MT; Stanley Center for Psychiatric Research, Broad Institute, Boston, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Nkambule LL; Stanley Center for Psychiatric Research, Broad Institute, Boston, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Madsen E; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Ghimire DJ; Population Studies Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Hermosilla S; Population Studies Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.; Department of Population and Family Health, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY, USA., Ge T; Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute, Boston, MA, USA., Martin AR; Stanley Center for Psychiatric Research, Broad Institute, Boston, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Axinn WG; Population Studies Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Smoller JW; Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute, Boston, MA, USA.

Publikováno v: Psychological medicine [Psychol Med] 2024 Sep 16, pp. 1-9. Date of Electronic Publication: 2024 Sep 16.

Association of neurotransmitter pathway polygenic risk with specific symptom profiles in psychosis.

Autor: Warren TL; Department of Neurobiology, Physiology and Behavior, University of California, Davis, CA, USA.; Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA.; Center for Neuroscience, University of California, Davis, CA, USA., Tubbs JD; Department of Psychiatry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lesh TA; Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA., Corona MB; Department of Neurobiology, Physiology and Behavior, University of California, Davis, CA, USA.; Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA.; Center for Neuroscience, University of California, Davis, CA, USA., Pakzad SS; Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA., Albuquerque MD; Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA., Singh P; Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA., Zarubin V; Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA.; Department of Psychology, Northwestern University, Evanston, IL, USA., Morse SJ; Department of Neurobiology, Physiology and Behavior, University of California, Davis, CA, USA.; Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA.; Center for Neuroscience, University of California, Davis, CA, USA.; Department of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO, USA., Sham PC; Department of Psychiatry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR. pcsham@hku.hk.; Centre for PanorOmic Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR. pcsham@hku.hk.; State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR. pcsham@hku.hk., Carter CS; Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA. cscarte1@hs.uci.edu.; Department of Psychiatry and Human Behavior, University of California, Irvine, CA, USA. cscarte1@hs.uci.edu., Nord AS; Department of Neurobiology, Physiology and Behavior, University of California, Davis, CA, USA. asnord@ucdavis.edu.; Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA. asnord@ucdavis.edu.; Center for Neuroscience, University of California, Davis, CA, USA. asnord@ucdavis.edu.

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2024 Aug; Vol. 29 (8), pp. 2389-2398. Date of Electronic Publication: 2024 Mar 15.

Whole-exome sequencing in a Chinese sample provides preliminary evidence for the link between rare/low-frequency immune-related variants and early-onset schizophrenia.

Autor: Zhong Y; Department of Psychiatry, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region of China., Tubbs JD; Department of Psychiatry, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region of China; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Leung PBM; Department of Psychiatry, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region of China; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Zhan N; Department of Psychiatry, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region of China., Hui TCK; Department of Psychiatry, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region of China., Ho KKY; Department of General Adult Psychiatry, Castle Peak Hospital, Hong Kong Special Administrative Region of China., Hung KSY; Department of General Adult Psychiatry, Castle Peak Hospital, Hong Kong Special Administrative Region of China., Cheung EFC; Department of General Adult Psychiatry, Castle Peak Hospital, Hong Kong Special Administrative Region of China., So HC; School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong Special Administrative Region of China; Department of Psychiatry, The Chinese University of Hong Kong, Shatin, Hong Kong Special Administrative Region of China. Electronic address: hcso@cuhk.edu.hk., Lui SSY; Department of Psychiatry, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region of China. Electronic address: lsy570@hku.hk., Sham PC; Department of Psychiatry, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region of China; Centre for PanorOmic Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region of China; State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong Special Administrative Region of China. Electronic address: pcsham@hku.hk.

Publikováno v: Asian journal of psychiatry [Asian J Psychiatr] 2024 Jun; Vol. 96, pp. 104046. Date of Electronic Publication: 2024 Apr 16.