Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Tuba Tüylü Küçükkılınç"'
Autor:
Elaheh Babaei, Tuba Tüylü Küçükkılınç, Leili Jalili-Baleh, Hamid Nadri, Esin Öz, Hamid Forootanfar, Elaheh Hosseinzadeh, Tayebeh Akbari, Mehdi Shafiee Ardestani, Loghman Firoozpour, Alireza Foroumadi, Mohammad Sharifzadeh, Bi Bi Fatemeh Mirjalili, Mehdi Khoobi
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Graphical AbstractA novel series of 3-phenyl-coumarin derivatives containing pyridinium salts was prepared, indicating significant inhibitory activity against AChE and BuChE as well as precious neuroprotective and anti-Aβ aggregation effects.
Externí odkaz:
https://doaj.org/article/18f48398801046ba83da797313fbfdca
Autor:
Ladan Pourabdi, Tuba Tüylü Küçükkılınç, Fatemeh Khoshtale, Beyza Ayazgök, Hamid Nadri, Farid Farokhi Alashti, Hamid Forootanfar, Tayebeh Akbari, Mohammad Shafiei, Alireza Foroumadi, Mohammad Sharifzadeh, Mehdi Shafiee Ardestani, M. Saeed Abaee, Loghman Firoozpour, Mehdi Khoobi, Mohammad M. Mojtahedi
Publikováno v:
Frontiers in Chemistry, Vol 9 (2022)
A novel series of coumarin derivatives linked to the N-benzyl triazole group were synthesized and evaluated against 15-lipoxygenase (15-LOX), and acetyl- and butyrylcholinesterase (AChE and BuChE) to find the most potent derivative against Alzheimer
Externí odkaz:
https://doaj.org/article/3b76a264a52647ad8fd2279f413de289
Autor:
Tuba Tüylü Küçükkılınç, Ayşe Ercan
Publikováno v:
Drug and Chemical Toxicology. :1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::517f1cff2fbaf598c4739054fe47616f
https://doi.org/10.1080/01480545.2023.2217696
https://doi.org/10.1080/01480545.2023.2217696
Autor:
Fereshteh Azimian, Mohammad Shahrivar-Gargari, Teymour vahedpour, Salar Hemmati, Mahrokh Dastmalchi, Tuba Tüylü Küçükkılınç, Siavoush Dastmalchi
Molecular hybridization and bioisosteric replacement approaches were used to design novel agents with potential use for the treatment of Alzheimer’s disease (AD). Derivatives containing indanone-chalcone core structure bearing ester group were desi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59a53307e442b25b87d2ad47e93c3b8f
https://doi.org/10.21203/rs.3.rs-2640623/v1
https://doi.org/10.21203/rs.3.rs-2640623/v1
Autor:
Ali Khennoufa, Salah Belaidi, Saida Khamouli, Touhami Lanez, Elhafnaoui Lanez, C. Boubekri, Nadjiba Zegheb, Esin Öz, Tuba Tüylü Küçükkılınç
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 22:1426-1437
Background: Since the binding of estradiol to its receptor promotes breast cancer cell proliferation (in the ER+ tumours), many molecules targeting this protein have been synthesized to counteract the estradiol action. Ferrocene derivatives have prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2fd95e14b13e277fa5aedf3b7a03229
https://doi.org/10.2174/1871520621666210624141712
https://doi.org/10.2174/1871520621666210624141712
Autor:
Ayse Ercan, Seyed Jalal Hosseinimehr, Hamid Irannejad, Nima Naderi, Tuba Tüylü Küçükkılınç, Sakineh Dadashpour
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 19:2120-2129
Background: Receptor Tyrosine Kinases (RTK) are the main family of cell surface receptors for growth factors, hormones and cytokines which are responsible for cell growth and differentiation and are considered as an important therapeutic target in ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6ee82f215c4f10ec6ef03fba37aa322
https://doi.org/10.2174/1871520619666190808152051
https://doi.org/10.2174/1871520619666190808152051
Autor:
Zafer Sahin, Sevde Nur Biltekin, Leyla Yurttaş, Barkin Berk, Tuba Tüylü Küçükkılınç, Şeref Demirayak
Donepezil is the most prescribed drug for mild to moderate Alzheimer's Disease. There is not any alternative drug with this potency yet. New scaffolds bearing benzofurans and amines are being tested for good potency on acetylcholinesterase enzyme to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec03994aec12e2f89378c927a605a15
https://hdl.handle.net/20.500.12511/9453
https://hdl.handle.net/20.500.12511/9453
Autor:
Ladan, Pourabdi, Tuba Tüylü, Küçükkılınç, Fatemeh, Khoshtale, Beyza, Ayazgök, Hamid, Nadri, Farid, Farokhi Alashti, Hamid, Forootanfar, Tayebeh, Akbari, Mohammad, Shafiei, Alireza, Foroumadi, Mohammad, Sharifzadeh, Mehdi, Shafiee Ardestani, M Saeed, Abaee, Loghman, Firoozpour, Mehdi, Khoobi, Mohammad M, Mojtahedi
Publikováno v:
Frontiers in Chemistry
A novel series of coumarin derivatives linked to the N-benzyl triazole group were synthesized and evaluated against 15-lipoxygenase (15-LOX), and acetyl- and butyrylcholinesterase (AChE and BuChE) to find the most potent derivative against Alzheimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4be9c9135503e9902f855a2dd9f086b4
https://pubmed.ncbi.nlm.nih.gov/35127652
https://pubmed.ncbi.nlm.nih.gov/35127652
Autor:
Tuba Tüylü Küçükkılınç, Esin Öz
Publikováno v:
Drug and chemical toxicology. 45(5)
Bisphenol A (BPA) is an endocrine-disrupting chemical utilized in the manufacture of food packaging, dental materials, medical devices, children's toys, and baby products. Numerous studies have indicated the role of BPA in the etiology of many diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6757f8987bb767e81a09f08e9d4f4d
https://pubmed.ncbi.nlm.nih.gov/34100320
https://pubmed.ncbi.nlm.nih.gov/34100320
Publikováno v:
Pharmaceutical Chemistry Journal. 53:322-328
The occurrence of amyloid-β (Aβ) and reduced cholinergic tranmission are two major hallmarks of Alzheimer’s disease (AD). Therefore, a series of new 2-phenylbenzo[d]thiazoles substituted with azole/piperazine moieties were designed, synthesized,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b60ea35a5d11db241052d61319b0c50d
https://doi.org/10.1007/s11094-019-02000-4
https://doi.org/10.1007/s11094-019-02000-4