Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Tuba Cuez"'
Autor:
Demet Unsal, John R. Falck, Wolf-Hagen Schunck, Ayse Nihal Sari, Meltem Kacan, C. Kemal Buharalioglu, Belma Korkmaz, Mehmet Sami Serin, Tuba Cuez, Kafait U. Malik, Bahar Tunctan, Seyhan Sahan-Firat
Publikováno v:
Prostaglandins & Other Lipid Mediators. :31-41
We have previously demonstrated that a stable synthetic analog of 20-HETE, N-[20-hydroxyeicosa-5(Z),14(Z)-dienoyl]glycine (5,14-HEDGE), restores vascular reactivity, blood pressure, and heart rate in endotoxemic rats. The aim of this study was to det
Autor:
C. Kemal Buharalioglu, Abdullah T. Demiryürek, Seyhan Sahan-Firat, A. Nihal Sari, Belma Korkmaz, Bahar Tunctan, Tuba Cuez
Publikováno v:
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry. 11:243-252
Oxidative stress and apoptosis are the states that can contribute to the pathogenesis of sepsis. In this study we aimed to investigate whether mitogen-activated protein kinase kinase 1 (MEK1)/extracellular signal-regulated kinase 1/2 (ERK1/2)/inducib
Autor:
Belma Korkmaz, Ayse Nihal Sari, Tuba Cuez, Seyhan Sahan-Firat, Bahar Tunctan, C. Kemal Buharalioglu, Kafait U. Malik
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 109:186-194
Nitric oxide (NO) produced by inducible NO synthase (iNOS) is responsible for endotoxin-induced vascular hyporeactivity and hypotension resulting in multiple organ failure. Endotoxic shock is also characterized by decreased expression of constitutive
Autor:
A. Tuncay Demiryurek, Tuba Cuez, Seyhan Sahan-Firat, Belma Korkmaz, Kemal Buharalioglu, Bahar Tunctan
Publikováno v:
Nitric Oxide. 24:160-172
Increased production of inducible nitric oxide (NO) synthase (iNOS)-derived NO contributes to fall in blood pressure and vascular reactivity during endotoxemia. We investigated whether an increase in protein expression and activity of the enzymes inv
Autor:
C. Kemal Buharalioglu, Kafait U. Malik, Tuba Cuez, Bahar Tunctan, Seyhan Sahan-Firat, John R. Falck, Belma Korkmaz
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 106:378-388
Nitric oxide (NO) produced by inducible NO synthase (iNOS) is responsible for endotoxin (ET)-induced hypotension and vascular hyporeactivity and plays a major contributory role in the multiorgan failure. Endotoxic shock is also associated with an inc
Autor:
Bahar Tunctan, C. Kemal Buharalioglu, Necmiye Canacankatan, Lülüfer Tamer Gümüş, Aysegul Gorur, Belma Korkmaz, Meltem Kacan, Tuba Cuez, Seyhan Şahan Fırat, Nehir Sucu, Özden Vezir, Lokman Ayaz, Demet Unsal, A. Nihal Sari
The small G protein RhoA and its downstream effector Rho-kinase play an important role in various physiopathological processes including ischemia/reperfusion (I/R) injury. Reactive oxygen and nitrogen species produced by iNOS and NADPH oxidase are im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27bb5a6c3e732ef33358fb7bd47ce62
https://aperta.ulakbim.gov.tr/record/65705
https://aperta.ulakbim.gov.tr/record/65705
Autor:
Meltem Kacan, Mehmet Sami Serin, Seyhan Sahan-Firat, Tuba Cuez, Wolf-Hagen Schunck, Demet Unsal, Bahar Tunctan, Belma Korkmaz, Ayse Nihal Sari, C. Kemal Buharalioglu, John R. Falck, Vijaya L. Manthati, Kafait U. Malik
We have previously demonstrated that a stable synthetic analog of 20-hydroxyeicosatetraenoic acid (20-HETE), N-[20-hydroxyeicosa-5(Z),14(Z)-dienoyl]glycine(5,14-HEDGE), prevents vascular hyporeactivity, hypotension, tachycardia, and inflammation in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d84cc9e48f54984ba71367eb96ad87f
https://europepmc.org/articles/PMC3759626/
https://europepmc.org/articles/PMC3759626/
Autor:
C Kemal, Buharalioglu, Belma, Korkmaz, Tuba, Cuez, Seyhan, Sahan-Firat, Ayse Nihal, Sari, Kafait U, Malik, Bahar, Tunctan
Publikováno v:
Basicclinical pharmacologytoxicology. 109(3)
Nitric oxide (NO) produced by inducible NO synthase (iNOS) is responsible for endotoxin-induced vascular hyporeactivity and hypotension resulting in multiple organ failure. Endotoxic shock is also characterized by decreased expression of constitutive
Autor:
C. Kemal Buharalioglu, Kafait U. Malik, Belma Korkmaz, Tuba Cuez, John R. Falck, Seyhan Sahan-Firat, Bahar Tunctan
Publikováno v:
Basic & Clinical Pharmacology & Toxicology.
Our previous studies with the use of non-selective cyclooxygenase (COX) inhibitor, indomethacin, demonstrated that prostanoids produced during endotoxaemia increase inducible nitric oxide synthase (iNOS) protein expression and nitric oxide synthesis,
Autor:
Tuba, Cuez, Belma, Korkmaz, C Kemal, Buharalioglu, Seyhan, Sahan-Firat, John, Falck, Kafait U, Malik, Bahar, Tunctan
Publikováno v:
Basicclinical pharmacologytoxicology. 106(5)
Nitric oxide (NO) produced by inducible NO synthase (iNOS) is responsible for endotoxin-induced hypotension and vascular hyporeactivity and plays a major contributory role in the multiorgan failure. Endotoxic shock is also associated with an increase