Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Tuanzhu, Ha"'
Autor:
Tao Zhang, Linjian Chen, Gatkek Kueth, Emily Shao, Xiaohui Wang, Tuanzhu Ha, David L. Williams, Chuanfu Li, Min Fan, Kun Yang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Lactate significantly impacts immune cell function in sepsis and septic shock, transcending its traditional view as just a metabolic byproduct. This review summarizes the role of lactate as a biomarker and its influence on immune cell dynamics, empha
Externí odkaz:
https://doaj.org/article/bb3ec540e20c4e8c81cb59184d47cb01
Autor:
Kun Yang, Matthew Holt, Min Fan, Victor Lam, Yong Yang, Tuanzhu Ha, David L. Williams, Chuanfu Li, Xiaohui Wang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Coronavirus disease 2019 (COVID-19), an infectious respiratory disease propagated by a new virus known as Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), has resulted in global healthcare crises. Emerging evidence from patients with COV
Externí odkaz:
https://doaj.org/article/1a23de23f7eb41639724b208576b2fe8
Autor:
Hao Chen, Yuxing Hou, Yali Zhai, Jie Yang, Linli Que, Jichun Liu, Linming Lu, Tuanzhu Ha, Chuanfu Li, Yong Xu, Jiantao Li, Yuehua Li
Publikováno v:
Journal of Leukocyte Biology. 113:95-108
The polarization of macrophages to the M1 or M2 phenotype has a pivotal role in inflammatory response following myocardial ischemia/reperfusion injury. Peli1, an E3 ubiquitin ligase, is closely associated with inflammation and autoimmunity as an impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a32f6544289ee6854c336d6f61bf42c2
https://doi.org/10.1093/jleuko/qiac012
https://doi.org/10.1093/jleuko/qiac012
Autor:
Kun Yang, Jingjing Xu, Min Fan, Fei Tu, Xiaohui Wang, Tuanzhu Ha, David L. Williams, Chuanfu Li
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Recent evidence from cancer research indicates that lactate exerts a suppressive effect on innate immune responses in cancer. This study investigated the mechanisms by which lactate suppresses macrophage pro-inflammatory responses. Macrophages [Raw 2
Externí odkaz:
https://doaj.org/article/749f370ebcba41b8a3a2504ba1a0643d
Autor:
Min Fan, Kun Yang, Xiaohui Wang, Yana Wang, Fei Tu, Tuanzhu Ha, Li Liu, David L. Williams, Chuanfu Li
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
Angiogenesis is essential for cardiac functional recovery after myocardial infarction (MI). HSPA12B is predominately expressed in endothelial cells and required for angiogenesis. Yes-associated protein (YAP) plays an important role in tumor angiogene
Externí odkaz:
https://doaj.org/article/77c519d2c6b848528b8cacfe360d2a8c
Autor:
Fei Tu, Xiaohui Wang, Xia Zhang, Tuanzhu Ha, Yana Wang, Min Fan, Kun Yang, P. Spencer Gill, Tammy R. Ozment, Yuan Dai, Li Liu, David L. Williams, Chuanfu Li
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Endothelial cell dysfunction contributes to sepsis induced initiate immune response and the infiltration of immune cells into organs, resulting in organ injury. Heat shock protein A12B (HSPA12B) is predominantly expressed in endothelial cells. The pr
Externí odkaz:
https://doaj.org/article/3f680a12ee7342e8846b48eeffdef228
Autor:
Xia Zhang, Xiaohui Wang, Min Fan, Fei Tu, Kun Yang, Tuanzhu Ha, Li Liu, John Kalbfleisch, David Williams, Chuanfu Li
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Heat shock protein A12B (HSPA12B) is predominately expressed in endothelial cells (ECs) and has been reported to protect against cardiac dysfunction from endotoxemia or myocardial infarction. This study investigated the mechanisms by which endothelia
Externí odkaz:
https://doaj.org/article/e50118cf3bbe4ed1bef2b419bb1232f4
Autor:
Min, Fan, Kun, Yang, Xiaohui, Wang, Xia, Zhang, Jingjing, Xu, Fei, Tu, P Spencer, Gill, Tuanzhu, Ha, David L, Williams, Chuanfu, Li
Publikováno v:
Shock. 58:304-312
Introduction: Sepsis impaired vascular integrity results in multiple organ failure. Circulating lactate level is positively correlated with sepsis-induced mortality. We investigated whether lactate plays a role in causing endothelial barrier dysfunct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::924678e51987f46ef6c3032ff688c5bb
https://doi.org/10.1097/shk.0000000000001983
https://doi.org/10.1097/shk.0000000000001983
Autor:
Min Fan, Kun Yang, Xiaohui Wang, Linjian Chen, P. Spencer Gill, Tuanzhu Ha, Li Liu, Nicole H. Lewis, David L. Williams, Chuanfu Li
Publikováno v:
Science Advances. 9
High levels of lactate are positively associated with the prognosis and mortality in patients with heart attack. Endothelial-to-mesenchymal transition (EndoMT) plays an important role in cardiac fibrosis. Here, we report that lactate exerts a previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57c1524bfea7cde91e101db6a86e1651
https://doi.org/10.1126/sciadv.adc9465
https://doi.org/10.1126/sciadv.adc9465
Autor:
Yana Wang, Chuanfu Li, David L. Williams, Kun Yang, P. Spencer Gill, Xiaohui Wang, Jingjing Xu, Min Fan, Tuanzhu Ha, Fei Tu, Li Liu
Publikováno v:
Cell Death and Differentiation
High circulating levels of lactate and high mobility group box-1 (HMGB1) are associated with the severity and mortality of sepsis. However, it is unclear whether lactate could promote HMGB1 release during sepsis. The present study demonstrated a nove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc7a1e1d32e0149a887f8668032bda8
https://doi.org/10.1038/s41418-021-00841-9
https://doi.org/10.1038/s41418-021-00841-9