Direct in vitro propagation of avian germ cells from an embryonic gonad biorepository

Autor: Tuanjun Hu, Phillip H. Purdy, Marcel H. Blank, Christine K. Muhonja, Ricardo J.G. Pereira, Christian K. Tiambo, Mike J. McGrew

Publikováno v: Poultry Science, Vol 103, Iss 11, Pp 104260- (2024)

ABSTRACT: Direct introduction of cryopreserved embryonic gonadal germ cells (GGC) into a sterile chicken surrogate host to reconstitute a chicken breed has been demonstrated as a feasible approach for preserving and utilizing chicken genetic resource

Externí odkaz: https://doaj.org/article/b33b17dae9ee40cda6ccad0bea3acfb9

Direct allele introgression into pure chicken breeds using Sire Dam Surrogate (SDS) mating

Autor: Maeve Ballantyne, Mark Woodcock, Dadakhalandar Doddamani, Tuanjun Hu, Lorna Taylor, Rachel J. Hawken, Mike J. McGrew

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)

Chicken are a biological model and an important agricultural animal. Here, the authors demonstrate that pure breed genome edited chicks can be produced for any chicken breed by direct mating of sterile surrogate hosts carrying donor genome edited ger

Externí odkaz: https://doaj.org/article/75f0f8bf6d594f2a9a0984334eb1c7c0

Avian Primordial Germ Cells Are Bipotent for Male or Female Gametogenesis

Autor: Maeve Ballantyne, Lorna Taylor, Tuanjun Hu, Dominique Meunier, Sunil Nandi, Adrian Sherman, Brenda Flack, John M. Henshall, Rachel J. Hawken, Mike J. McGrew

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

In birds, males are the homogametic sex (ZZ) and females are the heterogametic sex (ZW). Here, we investigate the role of chromosomal sex and germ cell competition on avian germ cell differentiation. We recently developed genetically sterile layer co

Externí odkaz: https://doaj.org/article/4d9c482c3f8749839e44880e8641f1db

Direct allele introgression into pure chicken breeds using Sire Dam Surrogate (SDS) mating

Autor: Rachel Hawken, Mark Woodcock, Maeve Ballantyne, Dadakhalandar Doddamani, Michael J. McGrew, Lorna Taylor, Tuanjun Hu

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Ballantyne, M, Woodcock, M, Doddamani, D, Hu, T, Taylor, L, Hawken, R J & McGrew, M 2021, ' Direct allele introgression into pure chicken breeds using Sire Dam Surrogate (SDS) mating ', Nature Communications . https://doi.org/10.1038/s41467-020-20812-x
Nature Communications

Poultry is the most abundant livestock species with over 60 billion chickens raised globally per year. The majority of chicken are produced from commercial flocks, however many indigenous chicken breeds play an important role in rural economies as th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85804c9d357f9b1d8db9211d3209ce28
https://doaj.org/article/75f0f8bf6d594f2a9a0984334eb1c7c0

Development of novel reagents to chicken FLT3, XCR1 and CSF2R for the identification and characterisation of avian conventional dendritic cells

Autor: Cosmin Chintoan-Uta, Adam Balic, David A. Hume, Zhiguang Wu, Mark P. Stevens, Joni Macdonald, Peter K. Kaiser, Tuanjun Hu, Helen Sang

Publikováno v: Wu, Z, Hu, T, Chintoan-Uta, C, Macdonald, J, Stevens, M P, Sang, H, Hume, D A, Kaiser, P & Balic, A 2021, ' Development of novel reagents to chicken FLT3, XCR1 and CSF2R for the identification and characterisation of avian conventional dendritic cells ', Immunology, vol. 165, pp. 171-194 . https://doi.org/10.1111/imm.13426

Conventional dendritic cells (cDC) are bone marrow derived immune cells that play a central role in linking innate and adaptive immunity. cDCs efficiently uptake, process, and present antigen to naïve T cells, driving clonal expansion of antigen spe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8167874b33c5cb9dd6daa00670f69bd3
https://www.pure.ed.ac.uk/ws/files/244119725/imm.13426.pdf