Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tu H, Mai"'
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 17 (2023)
Drug development for idiopathic pulmonary fibrosis (IPF) has been challenging due to poorly understood disease etiology, unpredictable disease progression, highly heterogeneous patient populations, and a lack of robust pharmacodynamic biomarkers. Mor
Externí odkaz:
https://doaj.org/article/7ed64f35735f4e8b93c52da7e6478dc7
Autor:
Yen Lin, Chia, Raj, Tummala, Tu H, Mai, Tomas, Rouse, Katie, Streicher, Wendy I, White, Eric F, Morand, Richard A, Furie
Publikováno v:
The Journal of Clinical Pharmacology. 62:1094-1105
This study aimed to elucidate the pharmacokinetic/pharmacodynamic and pharmacodynamic/efficacy relationships of anifrolumab, a type I interferon receptor antibody, in patients with moderate to severe systemic lupus erythematosus. Data were pooled fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::821efe577a03274d540e7843b56b0f14
https://doi.org/10.1002/jcph.2054
https://doi.org/10.1002/jcph.2054
Autor:
Makiko Harada, Hua Fang, Houda Alachkar, Makda Zewde, Kazuma Kiyotani, Poh Yin Yew, Xiao Liu, Tu H Mai, Kai Lee Yap, Tatsuo Matsuda, Yuji Ikeda, Jae-Hyun Park, Yusuke Nakamura, Taigo Kato, Boya Deng, Lili Ren
Publikováno v:
Journal of Human Genetics. 63:865-875
Although germline alterations and somatic mutations in disease cells have been extensively analyzed, molecular changes in immune cells associated with disease conditions have not been characterized in depth. It is clear that our immune system has a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f07f1c151d56065bdf53947c5e3ec93
https://doi.org/10.1038/s10038-018-0468-1
https://doi.org/10.1038/s10038-018-0468-1
Autor:
Yusuke Nakamura, A. Wesley Burks, Tu H Mai, Kazuma Kiyotani, Kelly Orgel, Seiya Imoto, Poh Yin Yew, Rui Yamaguchi, Mike Kulis, Satoru Miyano
Publikováno v:
Journal of Human Genetics. 63:239-248
B-cell receptors (BCRs) play a critical role in adaptive immunity as they generate highly diverse immunoglobulin repertoires to recognize a wide variety of antigens. To better understand immune responses, it is critically important to establish a qua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31513db710943cc08ee9b5af31257547
https://doi.org/10.1038/s10038-017-0364-0
https://doi.org/10.1038/s10038-017-0364-0
Publikováno v:
Journal of Human Genetics
Accurate human leukocyte antigen (HLA) genotyping is critical in studies involving the immune system. Several algorithms to estimate HLA genotypes from whole-exome data were developed. We compared the accuracy of seven algorithms, including Optitype,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbedca37678ce17549aa6a0a62eb1b9
http://europepmc.org/articles/PMC5334549
http://europepmc.org/articles/PMC5334549
Increased blood pressure (BP) is observed in patients with impaired baroreflexes after water drinking. The stimulus for this effect is low blood osmolality, and it has been termed the osmopressor response (OPR). The BP increase is associated with act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31f6d11d1f21aae465ec0e06e9a50e9
https://europepmc.org/articles/PMC5530865/
https://europepmc.org/articles/PMC5530865/
Calcitonin gene-related peptide (CGRP) in autonomic cardiovascular regulation and vascular structure
Publikováno v:
Journal of the American Society of Hypertension. 8:286-296
Calcitonin gene-related peptide (CGRP) is reported to play important roles in cardiovascular regulation in human and animal models. In spite of this, its role remains controversial. We aim to clarify this by studying the autonomic cardiovascular func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2cdb0db3c90c296651614c0484fdd03
https://doi.org/10.1016/j.jash.2014.03.001
https://doi.org/10.1016/j.jash.2014.03.001