Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tuğçe Aktaş"'
Autor:
Alexandra Bergfort, Marco Preußner, Benno Kuropka, İbrahim Avşar Ilik, Tarek Hilal, Gert Weber, Christian Freund, Tuğçe Aktaş, Florian Heyd, Markus C. Wahl
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Bergfort et al. use biochemistry, cryoEM, structure-guided mutagenesis, transcriptomics and proteomics to reveal how the intrinsically unstructured C9ORF78 protein binds BRR2 and PRPF8, regulating cassette exons and alternative 3’-splice sites.
Externí odkaz:
https://doaj.org/article/9cdd9c825b2e49b8b316d5d1c8d55312
Autor:
İbrahim Avşar Ilik, Michal Malszycki, Anna Katharina Lübke, Claudia Schade, David Meierhofer, Tuğçe Aktaş
Publikováno v:
eLife, Vol 9 (2020)
Nuclear speckles (NS) are among the most prominent biomolecular condensates. Despite their prevalence, research on the function of NS is virtually restricted to colocalization analyses, since an organizing core, without which NS cannot form, remains
Externí odkaz:
https://doaj.org/article/2686ad69ff9f484ab363499b8693b19f
Autor:
Alexandra Bergfort, Tarek Hilal, Benno Kuropka, İbrahim Avşar Ilik, Gert Weber, Tuğçe Aktaş, Christian Freund, Markus C Wahl
Publikováno v:
Nucleic Acids Research (London)
Biogenesis of spliceosomal small nuclear ribonucleoproteins (snRNPs) and their recycling after splicing require numerous assembly/recycling factors whose modes of action are often poorly understood. The intrinsically disordered TSSC4 protein has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0499513ffacd2dcbb3714aef9a0ddb56
Autor:
Tuğçe Aktaş Engin, Erdal Çokça
Publikováno v:
Arabian Journal of Geosciences. 14
The objective of this study is to find out the constant that shows a linear relationship between the deformation modulus parameter of Ankara clay and SPT N60 values by using Plaxis 2D software. During analyses, three constitutive models are used, tho
Autor:
Alexandra, Bergfort, Marco, Preußner, Benno, Kuropka, İbrahim Avşar, Ilik, Tarek, Hilal, Gert, Weber, Christian, Freund, Tuğçe, Aktaş, Florian, Heyd, Markus C, Wahl
Publikováno v:
Nature communications. 13(1)
The intrinsically unstructured C9ORF78 protein was detected in spliceosomes but its role in splicing is presently unclear. We find that C9ORF78 tightly interacts with the spliceosome remodeling factor, BRR2, in vitro. Affinity purification/mass spect
Autor:
Markus Kellner, Julia Hörmann, Susanne Fackler, Yuanyu Hu, Tielin Zhou, Lin Lu, Ibrahim Ilik, Tugce Aktas, Regina Feederle, Stefanie M. Hauck, Olivier Gires, Kathrin Gärtner, Lietao Li, Reinhard Zeidler
Publikováno v:
Cells, Vol 13, Iss 18, p 1563 (2024)
The membrane composition of extracellular vesicles (EVs) largely reflects that of the plasma membrane of the cell of origin. We therefore hypothesized that EVs could be used for immunizations to generate monoclonal antibodies against well-known tumor
Externí odkaz:
https://doaj.org/article/d3cd5443d9214ae6b3b43c2407cb6346
Autor:
Erdal Çokça, Tuğçe Aktaş
Publikováno v:
Computer Applications in Engineering Education. 26:1324-1335
Publikováno v:
Springer Series in Geomechanics and Geoengineering ISBN: 9783319971148
World population increases day by day. In order to meet this increasing population’s basic needs such as sheltering, transportation and social activities, necessity for underground structures gradually increase. As a result, deep excavations become
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76ce4fe0ae9e607c5542714f97573659
https://doi.org/10.1007/978-3-319-97115-5_1
https://doi.org/10.1007/978-3-319-97115-5_1
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
RNA-binding proteins have important roles in gene expression and regulation. Here the authors develop uvCLAP to purify proteins and determine their binding sites without the use of radioactivity.
Externí odkaz:
https://doaj.org/article/28437366da674ac9985b0fd4e479430d
Autor:
Tomasz Chelmicki, Friederike Dündar, Matthew James Turley, Tasneem Khanam, Tugce Aktas, Fidel Ramírez, Anne-Valerie Gendrel, Patrick Rudolf Wright, Pavankumar Videm, Rolf Backofen, Edith Heard, Thomas Manke, Asifa Akhtar
Publikováno v:
eLife, Vol 3 (2014)
Histone acetyl transferases (HATs) play distinct roles in many cellular processes and are frequently misregulated in cancers. Here, we study the regulatory potential of MYST1-(MOF)-containing MSL and NSL complexes in mouse embryonic stem cells (ESCs)
Externí odkaz:
https://doaj.org/article/2fea0fba0f7b4f778c57f42e9d0b07f8