Výsledky vyhledávání - "Tsz Yan Chong"

Abstract 5394: Uterine leiomyosarcoma with homologous recombination deficiency is highly sensitive to polo-like kinase 4 inhibitor

Autor: Tsz Yan Chong, Horace HY Lee, Judy WP Yam, Kin Long Chow, Ho Shing Wong, Ka Yu Tse, Mark R. Bray, Tak Wah Mak, Philip PC Ip

Publikováno v: Cancer Research. 82:5394-5394

INTRODUCTION: Uterine leiomyosarcoma (LMS) is rare and aggressive and without a well-established cancer-driver. Treatment is mainly surgical because most other therapies have limited benefits. Polo-like kinase 4 (PLK4) is a modulator of centriole dup

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c221430586a7577cf1f7b9bf981a9bc
https://doi.org/10.1158/1538-7445.am2022-5394

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Abstract 4130: Improvement of drug efficacy of polo-like kinase 4 inhibitor in the treatment of uterine leiomyosarcoma

Autor: Ka Yu Tse, Mark R. Bray, Tak W. Mak, Hok Yeung Horace Lee, Tsz Yan Chong, Philip Pc Ip, Kin Long Chow, Ho Shing Wong

Publikováno v: Cancer Research. 80:4130-4130

Introduction: Uterine leiomyosarcoma (Ut-LMS) is aggressive. Recurrence usually develops in 50 - 70% of patients and effective chemotherapy regime are limited. Polo-like kinase 4 (PLK4) is vital modulator of centriole duplication and cell mitotic pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63a523ee22416bd8a2462a081f6e084b
https://doi.org/10.1158/1538-7445.am2020-4130

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