Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tsz Tung Kwong"'
Autor:
Xiaoyu Liu, Man Liu, Haoran Wu, Wenshu Tang, Weiqin Yang, Thomas T.H. Chan, Lingyun Zhang, Shufen Chen, Zhewen Xiong, Jianxin Liang, Willis Wai-Yiu Si-Tou, Ting Shu, Jingqing Li, Jianquan Cao, Chengpeng Zhong, Hanyong Sun, Tsz Tung Kwong, Howard H.W. Leung, John Wong, Paul Bo-San Lai, Ka-Fai To, Tingxiu Xiang, Joseph Jao-Yiu Sung, Stephen Lam Chan, Jingying Zhou, Alfred Sze-Lok Cheng
Publikováno v:
JHEP Reports, Vol 6, Iss 7, Pp 101087- (2024)
Background & Aims: Recent studies demonstrated the importance of fibrosis in promoting an immunosuppressive liver microenvironment and thereby aggressive hepatocellular carcinoma (HCC) growth and resistance to immune checkpoint blockade (ICB), partic
Externí odkaz:
https://doaj.org/article/548a0fa4c9c849b8b8cb170ca38dbeaf
Autor:
Tsz Tung Kwong, Chi Hang Wong, Jing Ying Zhou, Alfred Sze Lok Cheng, Joseph Jao Yiu Sung, Anthony Wing Hung Chan, Stephen Lam Chan
Publikováno v:
JHEP Reports, Vol 3, Iss 2, Pp 100224- (2021)
Background & aims: Immune checkpoint blockade (ICB) has been approved for treatment of hepatocellular carcinoma (HCC). However, many patients with advanced HCC are non-responders to ICB monotherapy. Cytotoxic chemotherapy has been proposed to modulat
Externí odkaz:
https://doaj.org/article/a6f98b12474d47d587e8081f2e31470b
Autor:
Zhewen Xiong, Chan, Stephen Lam, Jingying Zhou, Vong, Joaquim S. L., Tsz Tung Kwong, Xuezhen Zeng, Haoran Wu, Jianquan Cao, Yalin Tu, Yu Feng, Weiqin Yang, Pak-Chun Wong, Patrick, Willis Wai-Yiu Si-Tou, Xiaoyu Liu, Jing Wang, Wenshu Tang, Zhixian Liang, Jiahuan Lu, Ka Man Li, Jie-Ting Low
Publikováno v:
Gut; Sep2023, Vol. 72 Issue 9, p1-16, 16p
Autor:
Alfred S. L. Cheng, Chi Hang Wong, Joseph J.Y. Sung, Anthony W.H. Chan, Jing Ying Zhou, Stephen L. Chan, Tsz Tung Kwong
Publikováno v:
JHEP Reports
JHEP Reports, Vol 3, Iss 2, Pp 100224-(2021)
JHEP Reports, Vol 3, Iss 2, Pp 100224-(2021)
Background & aims Immune checkpoint blockade (ICB) has been approved for treatment of hepatocellular carcinoma (HCC). However, many patients with advanced HCC are non-responders to ICB monotherapy. Cytotoxic chemotherapy has been proposed to modulate
Publikováno v:
Abstracts.
Background The heterogeneity and diverse pathogenic conditions of HCC construct an immunosuppressive tumor microenvironment (TME) which may lead to low immune checkpoint blockade (ICB) therapeutic responsiveness. Therefore, alleviating immunosuppress
Autor:
Clarence T. T. Wong, Dennis K. P. Ng, Tsz Tung Kwong, Jacky C.H. Chu, Gaole Dai, Roy C. H. Wong, Summer Y. Y. Ha, Chi Hang Wong
Publikováno v:
Organic letters. 22(18)
A phthalaldehyde-substituted phthalocyanine has been synthesized that can conjugate with a range of biomolecules, including peptides, monosaccharides, lipids, and DNAs, and be immobilized on the surface of bovine serum album nanoparticles and glass s
Autor:
Alfred S. L. Cheng, Jing Ying Zhou, Tsz Tung Kwong, Anthony W.H. Chan, Stephen L. Chan, Chi Hang Wong
Publikováno v:
Cancer Research. 80:954-954
Introduction: Intrinsic immunologic composition in liver tumor microenvironment (TME) may play a role in the heterogenous response towards immune-checkpoint blockade in hepatocellular carcinoma (HCC). In some cancers, it has been shown that cytotoxic
Autor:
Anthony W.H. Chan, Alfred S. L. Cheng, Jing Ying Zhou, Stephen L. Chan, Tsz Tung Kwong, C.H. Wong
Publikováno v:
Annals of Oncology. 30:xi54
Background Current hepatocellular carcinoma (HCC) immunotherapy trials only yield modest outcome, suggesting that possibly strong intrinsic immunosuppressive network needed to be tackled. Conventional chemotherapies are found to exert immunomodulator
Publikováno v:
Cancer Research. 77:1241-1241
Background: Arginine deprivation is a novel approach for cancer treatment as some cancers were found to be arginine auxotrophic. PEG-BCT-100, a pegylated form of recombinant human arginase, was used to investigate the effect of arginine deprivation o