Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Tsz Ming Ip"'
Publikováno v:
Applied Sciences, Vol 13, Iss 13, p 7920 (2023)
Currently, people spend many more hours on smartphones, and the potential impact of phone radiation is receiving more attention. Reducing the impact of a phone’s magnetic field on human health is vital. Although many studies advise changing phone u
Externí odkaz:
https://doaj.org/article/14f2561b632b4aee82f866fb2e293c8c
Publikováno v:
Redox Biology, Vol 34, Iss , Pp 101573- (2020)
Development of Keap1–Nrf2 interaction inhibitors is a promising strategy for the discovery of therapeutic agents against oxidative stress-mediated diseases. Two motifs of Nrf2, ETGE and DLG motif, are responsible for Keap1-Nrf2 binding. Previously,
Externí odkaz:
https://doaj.org/article/f171325debde4eca842033ea6fc9c387
Autor:
Yan Wang, Huang-Quan Lin, Chu-Ying Xiao, Wai-Kit Law, Jian-Shu Hu, Tsz-Ming Ip, David Chi-Cheong Wan
Publikováno v:
Journal of Functional Foods, Vol 20, Iss , Pp 159-170 (2016)
The inhibition of fatty acid binding protein 4 (FABP4) by using small molecules could potentially provide therapeutic opportunities for metabolic disorders treatment. According to the results of our in-house virtual screening on the herbal molecules
Externí odkaz:
https://doaj.org/article/39a7c989900e4b3795916e6572b59892
Publikováno v:
Redox Biology, Vol 34, Iss, Pp 101573-(2020)
Redox Biology
Redox Biology
Development of Keap1–Nrf2 interaction inhibitors is a promising strategy for the discovery of therapeutic agents against oxidative stress-mediated diseases. Two motifs of Nrf2, ETGE and DLG motif, are responsible for Keap1-Nrf2 binding. Previously,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ae15002026dea7ef891cf95bf10321
http://www.sciencedirect.com/science/article/pii/S2213231720305735
http://www.sciencedirect.com/science/article/pii/S2213231720305735
Autor:
Ping Wang, Yan Wang, Tsz Ming Ip, Yong-Tang Zheng, Huangquan Lin, Liu Meng Yang, Jianshu Hu, David Chi-Cheong Wan
Publikováno v:
Journal of Chemical Information and Modeling. 57:2336-2343
Protein-protein interaction between lens epithelium-derived growth factor (LEDGF/p75) and HIV-1 integrase becomes an attractive target for anti-HIV drug development. The blockade of this interaction by small molecules could potentially inhibit HIV-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0168c1eb69e9309ec2b3d63b1f69d0
https://doi.org/10.1021/acs.jcim.7b00402
https://doi.org/10.1021/acs.jcim.7b00402
Autor:
Jianshu Hu, Yan Wang, David Chi-Cheong Wan, Huangquan Lin, Chu Ying Xiao, Tsz Ming Ip, Wai Kit Law
Publikováno v:
Journal of Functional Foods, Vol 20, Iss, Pp 159-170 (2016)
The inhibition of fatty acid binding protein 4 (FABP4) by using small molecules could potentially provide therapeutic opportunities for metabolic disorders treatment. According to the results of our in-house virtual screening on the herbal molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061ba8ef442698bde0ef33bff630d77e
http://www.sciencedirect.com/science/article/pii/S1756464615005356
http://www.sciencedirect.com/science/article/pii/S1756464615005356
Publikováno v:
Journal of Chemical Information and Modeling. 54:3046-3050
We first identified fluorescein, ketazolam, antrafenine, darifenacin, fosaprepitant, paliperidone, risperidone, pimozide, trovafloxacin, and levofloxacin as inhibitors of fatty acid binding protein 4 using molecular docking screening from FDA-approve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bef18919dedecb467063255ef134931
https://doi.org/10.1021/ci500503b
https://doi.org/10.1021/ci500503b
Autor:
Mary M.Y. Waye, Yan Wang, Wai Kit Law, David Chi-Cheong Wan, Wei-Cheng Liang, Tzi Bun Ng, Denis Tsz-Ming Ip, Wen Liang Pan
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2013 (2013)
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-based Complementary and Alternative Medicine : eCAM
Acetylcholinesterase inhibitors are prominent alternative in current clinical treatment for AD patients. Therefore, there is a continued need to search for novel AChEIs with good clinical efficacy and less side effects. By using our in-house natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2c51ab96700f3bc206bd5875a19d1c
https://doi.org/10.1155/2013/937370
https://doi.org/10.1155/2013/937370
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 23(12)
Background Traditionally, molecular docking is primarily employed to screen pure compounds; the top-ranking chemicals are subsequently selected for experimental validation. Unlike synthetic chemicals, most natural products are commercially unavailabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ee107b151a679189259e3b0055e02b
https://pubmed.ncbi.nlm.nih.gov/27765367
https://pubmed.ncbi.nlm.nih.gov/27765367
Autor:
Wan-Fu Yue, Yun-gen Miao, Jian-Mei Liu, Guang-Li Li, Chuan-Xi Zhang, Xing-hua Li, Denis Tsz-Ming Ip, Wan Chi Cheong David, Xiaofeng Wu
Publikováno v:
Molecular Biology Reports. 36:329-335
This novel orange fluorescent protein (OFP) emits brilliant orange fluorescent light. OFP has high fluorescence quantum yield, fast maturation rate, and stability, which imply this protein should be the most favorable biotechnological tools used to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110dbdc3b92b755204185f9a9d95686c
https://doi.org/10.1007/s11033-007-9183-2
https://doi.org/10.1007/s11033-007-9183-2