Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Tsvetelina I. Lazarova"'
Autor:
Dale M. Walker, Tsvetelina I. Lazarova, Steven W. Riesinger, Miriam C. Poirier, Terri Messier, Brian Cunniff, Vernon E. Walker
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The lack of anticancer agents that overcome innate/acquired drug resistance is the single biggest barrier to achieving a durable complete response to cancer therapy. To address this issue, a new drug family was developed for intracellular delivery of
Externí odkaz:
https://doaj.org/article/f4c45ff1604b44f9a8e00b84babc041b
Publikováno v:
ChemInform. 27
Treatment of aryl phenylsulfinates 5 (prepared from phenols 1 by reaction with phenylsulfinyl chloride) with AlCl3 at 25 °C furnishes good yields of the (phenylsulfinyl)phenols 2 via a ‘thia-Fries rearrangement.’
Publikováno v:
ChemInform. 28
Autor:
Michael J. Rynkiewicz, Robert E. Babine, James E. Strickler, Harold V Meyers, Lei Jin, Frank Bibbins, Tsvetelina I. Lazarova, Joan C. Gorga
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(19)
A series of functionalized aryl boronic acids were synthesized and evaluated as potential inhibitors of factor XIa. Crystal structures of the protein-inhibitor complexes led to the design and synthesis of second generation compounds showing single di
Publikováno v:
The Journal of Organic Chemistry. 62:1553-1555
Autor:
Sherin S. Abdel-Meguid, Tsvetelina I. Lazarova, Michael J. Rynkiewicz, Robert E. Babine, Pramod Pandey, Lei Jin, Hongfeng Deng, Jesse Quinn, Pamela Nagafuji, Joan C. Gorga, Frank Bibbins, Thomas D. Bannister, Jian Lin, Harold V Meyers, Cassandra Celatka, James E. Strickler
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(11)
Using an alpha-ketothiazole arginine moiety as a key recognition element, a series of small peptidomimetic molecules was designed and synthesized, and their co-crystal structures with factor XIa were studied in an effort to develop smaller, less pept
Publikováno v:
The Journal of Organic Chemistry. 64:2976-2977
Autor:
Wöhrle, Tobias1 tobias.woehrle@oc.uni-stuttgart.de, Baro, Angelika1 angelika.baro@oc.uni-stuttgart.de, Laschat, Sabine1 sabine.laschat@oc.uni-stuttgart.de
Publikováno v:
Materials (1996-1944). Sep2014, Vol. 7 Issue 9, p4045-4056. 27p. 1 Color Photograph, 3 Diagrams, 1 Chart, 3 Graphs.