Zobrazeno 1 - 10
of 432
pro vyhledávání: '"Tsuyoshi Takato"'
Autor:
Ryoko Inaki, Yoshihiko Sato, Daisuke Nakamura, Yoshiyuki Aikawa, Tsuyoshi Takato, Kazuto Hoshi, Atsuhiko Hikita
Publikováno v:
Regenerative Therapy, Vol 24, Iss , Pp 662-669 (2023)
Background: Cell therapy is a useful treatment method for wide spectrum of diseases which utilizes the immunosuppressive and regenerative abilities of administered cells. It is essential to build a transport system of tissues from which cells are har
Externí odkaz:
https://doaj.org/article/77cebaef1eec4294a7b3dd9c369ed900
Autor:
Tomohiko Watanabe, Yukiyo Asawa, Makoto Watanabe, Ryuji Okubo, Masaki Nio, Tsuyoshi Takato, Kazuto Hoshi, Atsuhiko Hikita
Publikováno v:
Regenerative Therapy, Vol 15, Iss , Pp 312-322 (2020)
In cartilage tissue engineering, research on materials for three-dimensional (3D) scaffold has attracted attention. Decellularized matrix can be one of the candidates for the scaffold material. In this study, decellularization of regenerated cartilag
Externí odkaz:
https://doaj.org/article/e2bae25ec6b74ff790fa79d8bfe4ed86
Autor:
Ryo Umeyama, Takanori Yamawaki, Dan Liu, Sanshiro Kanazawa, Tsuyoshi Takato, Kazuto Hoshi, Atsuhiko Hikita
Publikováno v:
Regenerative Therapy, Vol 14, Iss , Pp 284-295 (2020)
Introduction: Currently, various kinds of materials are used for the treatment of bone defects. In general, these materials have a problem of formativeness. The three -dimensional (3D) printing technique has been introduced to fabricate artificial bo
Externí odkaz:
https://doaj.org/article/90b45d4f2fe04f03850802594a9afadf
Autor:
Makoto Komura, Hiroko Komura, Ryosuke Satake, Keisuke Suzuki, Hironobu Yonekawa, Kenichi Ikebukuro, Hiroaki Komuro, Kazuto Hoshi, Tsuyoshi Takato, Takeshi Moriwaki, Yasuhide Nakayama
Publikováno v:
Regenerative Therapy, Vol 11, Iss , Pp 176-181 (2019)
Introduction: We devised a strategy for the fabrication of an ‘anatomy-mimicking’ cylinder-type engineered trachea combined with cartilage engineering. The engineered BIOTUBEs are used to support the architecture of the body tissue, for long-segm
Externí odkaz:
https://doaj.org/article/7c65fa5c9f3d43a286c964cffb56147d
Autor:
Ryuji Okubo, Yukiyo Asawa, Makoto Watanabe, Satoru Nagata, Masaki Nio, Tsuyoshi Takato, Atsuhiko Hikita, Kazuto Hoshi
Publikováno v:
Regenerative Therapy, Vol 11, Iss , Pp 306-315 (2019)
Introduction: Cartilage regeneration have been attracted attentions because of the poor ability of cartilage tissues to regenerate. Three-dimensional (3D) culture of chondrocytes is considered to be advantageous for cartilage regeneration. Although i
Externí odkaz:
https://doaj.org/article/15c4692d887a4c85a5a97e8d10a18a8e
Publikováno v:
Regenerative Therapy, Vol 9, Iss , Pp 58-70 (2018)
Introduction: Pluripotent stem cells have an advantage that they can proliferate without reduction of the quality, while they have risk of tumorigenesis. It is desirable that pluripotent stem cells can be utilized safely with minimal effort in cartil
Externí odkaz:
https://doaj.org/article/78c6d685257147aab3e20f733f287692
Autor:
Taro Tsujimura, Osamu Takase, Masahiro Yoshikawa, Etsuko Sano, Matsuhiko Hayashi, Tsuyoshi Takato, Atsushi Toyoda, Hideyuki Okano, Keiichi Hishikawa
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-17 (2018)
Abstract Background Contact domains of chromatin serve as a fundamental unit to regulate action of enhancers for target genes. Looping between a pair of CCCTC-binding factor (CTCF)-binding sites in convergent orientations underlies the formation of c
Externí odkaz:
https://doaj.org/article/21d3e1b888ca4dc0b086557c206f7e6d
Autor:
Taro Tsujimura, Osamu Takase, Masahiro Yoshikawa, Etsuko Sano, Matsuhiko Hayashi, Kazuto Hoshi, Tsuyoshi Takato, Atsushi Toyoda, Hideyuki Okano, Keiichi Hishikawa
Publikováno v:
eLife, Vol 9 (2020)
While regulation of gene-enhancer interaction is intensively studied, its application remains limited. Here, we reconstituted arrays of CTCF-binding sites and devised a synthetic topological insulator with tetO for chromatin-engineering (STITCH). By
Externí odkaz:
https://doaj.org/article/e842a9a8a27747c1b1211b39efd6f45f
Autor:
Takanori Yamawaki, Yuko Fujihara, Mikako Harata, Tsuyoshi Takato, Atsuhiko Hikita, Kazuto Hoshi
Publikováno v:
Regenerative Therapy, Vol 8, Iss , Pp 1-8 (2018)
Restoration of damaged cartilage tissue has been deemed futile with current treatments. Although there have been many studies on cartilage regeneration thus far, there is no report that chondrocytes were completely re-differentiated in vitro. The cla
Externí odkaz:
https://doaj.org/article/57bb23b5c2bb4a76ab9012b80b11135e
Autor:
Kazuto Hoshi, Yuko Fujihara, Hideto Saijo, Kumiko Kurabayashi, Hideyuki Suenaga, Yukiyo Asawa, Satoru Nishizawa, Sanshiro Kanazawa, Sakura Uto, Ryoko Inaki, Mariko Matsuyama, Tomoaki Sakamoto, Makoto Watanabe, Madoka Sugiyama, Kazumichi Yonenaga, Atsuhiko Hikita, Tsuyoshi Takato
Publikováno v:
Regenerative Therapy, Vol 7, Iss C, Pp 72-79 (2017)
Introduction: We have developed an implant-type tissue-engineered cartilage using a poly-l-lactide scaffold. In a clinical study, it was inserted into subcutaneous areas of nasal dorsum in three patients, to correct cleft lip–nose deformity. The ai
Externí odkaz:
https://doaj.org/article/0950363da6fe45789af52da82c7c5c99