Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Tsuyoshi Takasuka"'
Autor:
Satoshi Morita, Takashi Yamanaka, Takaki Sakurai, Yoshinori Ito, K. Ishida, Kenichi Inoue, Shinji Ohno, Hiroyuki Yasojima, Tatsuki R. Kataoka, Eiji Suzuki, Shoichiro Ohtani, Hiroko Bando, Tsuyoshi Takasuka, Toshimi Takano, Rikiya Nakamura, Masakazu Toi, Katsumasa Kuroi, Norikazu Masuda, Hiroi Kasai
Publikováno v:
Breast Cancer Research and Treatment
Purpose The standard of care in the neoadjuvant setting for human epidermal growth factor receptor 2 (HER2)-positive breast cancer is dual HER2-targeted therapy. However, a need to minimize treatment-related toxicity and improve pathological complete
Publikováno v:
Folia Pharmacologica Japonica. 143:95-102
Publikováno v:
Journal of Biological Chemistry. 277:41744-41749
Fks1p and Fks2p are catalytic subunits of beta-1,3-glucan synthase, which synthesize beta-1,3-glucan, a main component of the cell wall in Saccharomyces cerevisiae. Although Fks1p and Fks2p are highly homologous, sharing 88.1% identity, it has been s
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 143(2)
Autor:
Takahide Watanabe, Hiroshi Urakami, Tatsuo Ohta, Tsuyoshi Takasuka, Yasuhiro Furuichi, Tadazumi Komiyama, Misako Satoh, Yasuhiko Shiratori
Publikováno v:
Journal of Biochemistry. 119:731-736
The cytocidal effect of HM-1 produced by Hansenula mrakii on yeast Saccharomyces cerevisiae cells was studied. The HM-1 strongly inhibited the growth of S. cerevisiae cells at a low concentration (IC50: 2.1 x 10(-8) M) by reducing the number of viabl
Publikováno v:
Journal of Biological Chemistry. 269:7509-7513
ETB type endothelin receptor (ETBR) forms a stable complex with its ligand endothelin-1 (ET-1). The ligand-receptor complex can survive in the presence of 2% SDS and migrate in SDS-polyacrylamide gel electrophoresis at reduced temperature. This is no
Publikováno v:
Biochemical and Biophysical Research Communications. 176:392-400
We found that the complex of ET-1 and its binding protein was stable enough to be separated by SDS-PAGE when electrophoresis was run at a low temperature. Cross-linking was not necessary for the detection of [125I]-ET-1 and its binding protein comple
Publikováno v:
Cell Structure and Function. 16:315-321
tsJT16 is a G0/G1 ts mutant from the Fischer rat fibroblast line. It has a ts defect in a function operating early after growth stimulation with fetal bovine serum (FBS). A primarily induced gene product, p70, was not synthesized at 40 degrees C afte
Autor:
Mika Endo, Kazuko Kobayashi, Chikako Murasaki, Kenji Morikami, Kotaro Ogawa, Nobuo Shimma, Eitaro Nanba, Yoko Miyazaki, Isao Imperial Higashihak Umeda, Kiyoshi Yoshinari, Hiroshi Fukuda, Masako Ura, Satoshi Niizuma, Hitomi Suda, Takeshi Murata, Hisafumi Okabe, Tsuyoshi Takasuka, Jun Ohwada, Sawako Ozawa, Akira Kawashima, Hiromi Tanimura, Kounosuke Nakano, Masami Kohchi, Masao Tsukazaki
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(7)
Novel hexacyclic camptothecin analogs containing cyclic amidine, urea, or thiourea moiety were designed and synthesized based on the proposed 3D-structure of the topoisomerase I (Topo I)/DNA/camptothecin ternary complex. The analogs were prepared fro
Publikováno v:
Cell Structure and Function. 15:47-52
tsJT16 is a temperature-sensitive (ts) mutant of rat fibroblasts that has a ts defect in a function operating soon after the growth stimulation from the G0 phase. After the growth stimulation, the cells express several cell-cycle-dependent genes at b