Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tsuyoshi Takasaki"'
Autor:
Venkatesan, Aranapakam M., Agarwal, Atul, Abe, Takao, Ushirogochi, Hideki, Ado, Mihira, Tsuyoshi, Takasaki, Dos Santos, Osvaldo, Li, Zhong, Francisco, Gerry, Lin, Yang I., Petersen, Peter J., Yang, Youjun, Weiss, William J., Shlaes, David M., Mansour, Tarek S.
Publikováno v:
In Bioorganic & Medicinal Chemistry 2008 16(4):1890-1902
Autor:
Minoru Toshima, Mike Filios, Bhogle Nandkumar Nivritti, Katsuya Uchiyama, Kazuhiko Takahashi, John R. Snoonian, Hang Zhao, Kostas Saranteas, Shoji Watanabe, Tsuyoshi Takasaki
Publikováno v:
Organic Process Research & Development. 20:1239-1245
The process development of ethyl-(R)-3-amino-2,5-dioxopyrrolidine-3-carboxylate (2), the chiral intermediate for the manufacture of AS-3201 (1), is described. A practical and scalable Shibasaki asymmetric amination that generates the chiral quaternar
Autor:
Takao Abe, Tarek S. Mansour, Chisato Sato, Tsuyoshi Takasaki, Koichi Sato, Satoshi Tamai, and Aranapakam M. Venkatesan, Itsuki Yamamura, Ado Mihira, Takeshi Isoda, Motoo Shiro, Kazuhiko Hayashi, Hideki Ushirogochi, Toshio Kumagai
Publikováno v:
The Journal of Organic Chemistry. 69:5850-5860
A novel and mild method was established to synthesize 6-methylidene penem compounds. This method entails a MgBr(2)/Et(3)N-promoted aldol-type condensation on 6-bromopenem 12 with an appropriately substituted aldehyde to yield the intermediate acetyla
Autor:
Tomoko Yajima, Tsuyoshi Takasaki, Tadafumi Uchimaru, Masahiro Terada, Koichi Mikami, Masamichi Maruta, Satoru Matsukawa
Publikováno v:
Tetrahedron. 52:85-98
The chiral titanium complex-catalyzed ene-type reaction and the Mukaiyama aldol reaction with fluoral are shown to serve as an efficient route to the enantioselective and diastercoselective synthesis of CF 3 -substituted components of biological and
Autor:
Tomoko Yajima, Tsuyoshi Takasaki, Koichi Mikami, Tadafumi Uchimaru, Masahiro Terada, Masamichi Maruta, Satoru Matsukawa
Publikováno v:
ChemInform. 27
The chiral titanium complex-catalyzed ene-type reaction and the Mukaiyama aldol reaction with fluoral are shown to serve as an efficient route to the enantioselective and diastercoselective synthesis of CF 3 -substituted components of biological and
Publikováno v:
ChemInform. 27
Autor:
Ado Mihira, Itsuki Yamamura, Zhong Li, Takeshi Isoda, Atul Agarwal, Takao Abe, Koichi Sato, Hideki Ushirogochi, Toshio Kumagai, Youjun Yang, Tarek S. Mansour, Aranapakam Mudumbai Venkatesan, Tsuyoshi Takasaki
Publikováno v:
ChemMedChem. 2(12)
Autor:
Koichi Satoh, Toshio Kumagai, Satoshi Tamai, Yoshimitsu Nagao, Chisato Sato, Itsuki Yamamura, Hideki Ushirogochi, Tsuyoshi Takasaki, Ado Mihira, Takao Abe, Shigeki Yamamoto, Takeshi Isoda
Publikováno v:
The Journal of antibiotics. 59(4)
We discovered an orally active carbapenem, L-084, through pharmacokinetic studies on various prodrug esters of (1R,5S,6S)-6-[(R)-1-hydroxyethyl]-1-methyl-2-[1-(1,3-thiazolin-2-yl)azetidin-3-yl]thio-1-carbapen-2-em-3-carboxylic acid (LJC11,036). L-084
Publikováno v:
Synlett. 1995:1057-1058
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