Zobrazeno 1 - 10
of 290
pro vyhledávání: '"Tsuyoshi Shirai"'
Autor:
Sho Shimada, Tetsuo Yamaguchi, Satsuki Mikoshiba, Kazuaki Sato, Takahiro Mitsumura, Kohji Komori, Takashi Yamana, Yuki Iijima, Rie Sakakibara, Sho Shibata, Takayuki Honda, Tsuyoshi Shirai, Tsukasa Okamoto, Haruhiko Furusawa, Tomoya Tateishi, Yasunari Miyazaki
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-6 (2024)
Abstract Background The emergence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has increased the incidence of community-onset MRSA infection. Respiratory tract infections caused by MRSA has been noted for their severi
Externí odkaz:
https://doaj.org/article/b4f8f6a6f62c46acb49f1bba27051ec0
Autor:
Yuki Iijima, Masaru Ejima, Takashi Yamana, Shiro Sonoda, Sho Shibata, Tsuyoshi Shirai, Tsukasa Okamoto, Haruhiko Furusawa, Tomoya Tateishi, Takuya Adachi, Mio Mori, Susumu Kirimura, Tatsuhiko Anzai, Kunihiko Takahashi, Yasunari Miyazaki
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Exposure assessment is integral to the diagnosis of hypersensitivity pneumonitis (HP). Although the clinical relevance of exposed antigens is essential for the assessment, many of the previous guidelines or reports have only evalu
Externí odkaz:
https://doaj.org/article/3a37df6e54c64bbdb4ffe7fa33905a15
Autor:
Kohdai Yamada, Ryouhei Shioya, Kohei Nishino, Hirotake Furihata, Atsushi Hijikata, Mika K. Kaneko, Yukinari Kato, Tsuyoshi Shirai, Hidetaka Kosako, Tatsuya Sawasaki
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Receptor proteins, such as epidermal growth factor receptor (EGFR), interact with other proteins in the extracellular region of the cell membrane to drive intracellular signalling. Therefore, analysis of extracellular protein-protein interac
Externí odkaz:
https://doaj.org/article/e1786466eff242848bf775caca410fb3
Autor:
Ken Yasaka, Tomohide Yamazaki, Hiroko Sato, Tsuyoshi Shirai, Minkwon Cho, Koji Ishida, Koyu Ito, Tetsuhiro Tanaka, Kouetsu Ogasawara, Hideo Harigae, Tomonori Ishii, Hiroshi Fujii
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract Background In systemic lupus erythematosus (SLE), autoreactive B cells are thought to develop by-passing immune checkpoints and contribute to its pathogenesis. Toll-like receptor (TLR) 7 and 9 signaling have been implicated in their developm
Externí odkaz:
https://doaj.org/article/29939c8501f44150b969d210e4f2151e
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract TRPV1 plays an important role in the thermosensory system; however, the mechanism controlling its heat activation property is not well understood. Here, we determine the heat activation properties of TRPV1 cloned from tailed amphibians, whic
Externí odkaz:
https://doaj.org/article/66f7bdda925e4db2bc786dee6629f43f
Autor:
Tatsuro Nishikino, Atsushi Hijikata, Seiji Kojima, Tsuyoshi Shirai, Masatsune Kainosho, Michio Homma, Yohei Miyanoiri
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107320- (2023)
Summary: The FliG protein plays a pivotal role in switching the rotational direction of the flagellar motor between clockwise and counterclockwise. Although we previously showed that mutations in the Gly-Gly linker of FliG induce a defect in switchin
Externí odkaz:
https://doaj.org/article/15cd86dea7094e08a0eb72e4041528dd
Autor:
Kaoru Nomura, Shoko Mori, Kohki Fujikawa, Tsukiho Osawa, Shugo Tsuda, Kumiko Yoshizawa-Kumagaye, Shun Masuda, Hideki Nishio, Taku Yoshiya, Takao Yoda, Masafumi Shionyu, Tsuyoshi Shirai, Ken-ichi Nishiyama, Keiko Shimamoto
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Non-proteinaceous components in membranes regulate membrane protein insertion cooperatively with proteinaceous translocons. An endogenous glycolipid in the Escherichia coli membrane called membrane protein integrase (MPIase) is one such comp
Externí odkaz:
https://doaj.org/article/c4b649d714414d0ba65ed930bfcd743a
Autor:
Hiroyuki Sakashita, Ken Uchibori, Yasuto Jin, Toshiharu Tsutsui, Takayuki Honda, Rie Sakakibara, Takahiro Mitsumura, Yoshihisa Nukui, Tsuyoshi Shirai, Masahiro Masuo, Kozo Suhara, Haruhiko Furusawa, Takaaki Yamashita, Takehiko Ohba, Kazuhito Saito, Jun Takagiwa, Yoshihiro Miyashita, Naohiko Inase, Yasunari Miyazaki
Publikováno v:
Thoracic Cancer, Vol 13, Iss 9, Pp 1267-1275 (2022)
Abstract Background A standard treatment regimen for advanced non‐small cell lung cancer (NSCLC) patients with interstitial lung disease (ILD) has not been established since most clinical trials exclude such patients because of the high risk of acu
Externí odkaz:
https://doaj.org/article/fe5bbcf9dbb64b87b0926aa52b897ff9
Autor:
Kohei Okada, Rie Sakakibara, Takayuki Honda, Takahiro Mitsumura, Sho Shibata, Tsuyoshi Shirai, Tsukasa Okamoto, Haruhiko Furusawa, Tomoya Tateishi, Yasunari Miyazaki
Publikováno v:
Respiratory Medicine Case Reports, Vol 46, Iss , Pp 101929- (2023)
A 74-year-old man was referred to our hospital with an abnormal chest shadow. Computed tomography (CT) revealed a mass in the left upper lobe and interstitial pneumonia (IP). The patient underwent CT-guided needle biopsy and was diagnosed as lung ade
Externí odkaz:
https://doaj.org/article/005d6241cc6b4f9b8667b84218770c05
Autor:
Maki Gau, Ryota Suga, Atsushi Hijikata, Ayako Kashimada, Masatoshi Takagi, Ryuichi Nakagawa, Kei Takasawa, Tsuyoshi Shirai, Kenichi Kashimada, Tomohiro Morio
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
IntroductionNR5A1 and NR5A2 belong to an orphan nuclear receptor group, and approximately 60% of their amino acid sequences are conserved. Transcriptional regulation of NR5A receptors depends on interactions with co-factors or unidentified ligands.Pu
Externí odkaz:
https://doaj.org/article/035141c10a734bc786d2ea6ea7642a0f