Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tsuyoshi Shimoboji"'
Autor:
Haddad Antonia-Nancy, Yuto Iwatsuki, Kohei Yabuuchi, Shogo Aso, Toru Katsumata, Keisuke Fukumoto, Yurika Tanaka, Takashi Nakai, Tsuyoshi Shimoboji, Michiaki Matsumoto, Yoshiro Tahara
Publikováno v:
Biochemical Engineering Journal. 196:108955
Autor:
Tsuyoshi Shimoboji, Patrick S. Stayton, Niren Murthy, Chantal Lackey, Volga Bulmus, Mohamed E. H. ElSayed, Samarth Kulkarni, A. S. Hoffman
Publikováno v:
Proceedings of the IEEE. 93:726-736
Many molecular imaging techniques rely on tracer methods to visualize specific physiological processes in cells, animals, and humans. A new family of "smart" delivery systems for biomolecules has opened new opportunities for the molecular imaging fie
Autor:
Edmund A. Larenas, Patrick S. Stayton, Allan S. Hoffman, Tsuyoshi Shimoboji, Timothy Fowler, Samarth Kulkarni
Publikováno v:
Proceedings of the National Academy of Sciences. 99:16592-16596
The ability to photoregulate enzyme activities could provide important new opportunities for development of diagnostic assays, sequential bioprocessing, and lab assays in both traditional and microfluidic formats. We show here that the photoinduced c
Autor:
Ollie W. Press, Zhongli Ding, Morikazu Miura, Ashutosh Chilkoti, Cynthia J. Long, Niren Murthy, Nobuo Monji, Allan S. Hoffman, Patrick S. Stayton, Katsuhiko Nakamae, John H. Priest, Robin B. Fong, Takashi Nishino, Chuck Cheung, Sara G. Shoemaker, Jingping Chen, Heung Joon Yang, Carole Ann Cole, Takashi Miyata, Chantal Lackey, Robert C. Nowinski, Volga Bulmus, John E. Morris, Tsuyoshi Shimoboji, Guohua Chen, Yoshikuni Nabeshima, Tae Gwan Park, Liang-chang Dong, J. Milton Harris
Publikováno v:
Journal of Biomedical Materials Research. 52:577-586
Over the past 18 years we have been deeply involved with the synthesis and applications of stimuli-responsive polymer systems, especially polymer-biomolecule conjugates. This article summarizes our work with one of these conjugate systems, specifical
Autor:
Patrick S. Stayton, Ashutosh Chilkoti, Morikazu Miura, Zhongli Ding, Taegwan Park, Cindi Long, Jingping Chen, Nobuo Monji, Allan S. Hoffman, Tsuyoshi Shimoboji, Guohua Chen, Carol Ann Cole, J. Milton Harris, Katsuhiko Nakamae
Publikováno v:
Scopus-Elsevier
Intelligent polymers exhibit sharp, reversible phase changes in response to small changes in environmental conditions. For example, a small temperature change can cause a sharp precipitation or gelation of a smart polymer solution. Conjugation of the
Autor:
Mika Sato, Takayuki Nemoto, Kenji Yasugi, Tsuyoshi Shimoboji, Tai Hirakura, Nobuyuki Morimoto, Yoshinori Aso, Kazunari Akiyoshi
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 142(3)
Novel hybrid hyaluronan (HA) hydrogel encapsulating nanogels was designed for sustained delivery of protein. HA modified with 2-aminoethyl methacrylate was cross-linked via Michael addition in the presence of cholesteryl group-bearing pullulan (CHP)
Publikováno v:
International journal of biological macromolecules. 40(4)
Hyaluronic acid (HA) hydrogels prepared with three different crosslinking reagents were assessed by in vitro and in vivo degradation tests for various tissue engineering applications. Adipic acid dihydrazide grafted HA (HA-ADH) was synthesized and us
Publikováno v:
Journal of biomedical materials research. Part A. 78(3)
A novel sustained release formulation of erythropoietin (EPO) was developed using hyaluronic acid (HA) hydrogels. For the preparation of HA hydrogels, adipic acid dihydrazide grafted HA (HA-ADH) was synthesized and analyzed with (1)H NMR. The degree
Autor:
Allan S. Hoffman, Patrick S. Stayton, J. M. Harris, Tsuyoshi Shimoboji, Ashutosh Chilkoti, Cynthia J. Long, Guohua Chen
Publikováno v:
Nature. 378:472-474
Stimuli-responsive polymers exhibit reversible phase changes in response to changes in environmental factors such as pH or temperature. Conjugating such polymers to antibodies and proteins provides molecular systems for applications such as affinity
Publikováno v:
Bioconjugate chemistry. 13(5)
Light-regulated molecular switches that reversibly control biomolecular function could provide new opportunities for controlling activity in diagnostics, affinity separations, bioprocessing, therapeutics, and bioelectronics applications. Here we show