Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tsuyoshi Miyahara"'
Effects of Acetaminophen at Different High Doses (2.4-4.0 g/day) on Cancer Pain and Hepatic Toxicity
Autor:
Toshifumi Kosugi, Yuki Hachiya, Hisashi Matsunaga, Hidetoshi Sato, Tsuyoshi Miyahara, Naokuni Uike
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 42:605-612
Publikováno v:
Journal of Neurochemistry. 133:343-351
Obesity is a worldwide health problem that urgently needs to be solved. Leptin is an anti-obesity hormone that activates satiety signals to the brain. Evidence to suggest that leptin resistance is involved in the development of obesity is increasing;
Autor:
Tomomi Nakamura, Tomonori Abe, Naoko Sueoka-Aragane, Kazutoshi Komiya, Kentaro Iwanaga, Norio Ureshino, Shinya Kimura, Chiho Nakashima, Hisashi Matsunaga, Tsuyoshi Miyahara
Publikováno v:
Medical oncology (Northwood, London, England). 34(12)
Pemetrexed is a key anticancer agent for treatment of advanced non-small cell lung cancer (NSCLC). Pemetrexed is generally well tolerated, but individual-patient differences exist in severity of adverse events. Our study aimed to characterize the adv
Autor:
Naomi Hirakawa, Ayumi Nita, Tsuyoshi Miyahara, Hisashi Matsunaga, Naomi Mori, Hidetoshi Sato, Sasagu Hamada, Toshifumi Kosugi, Yuki Hachiya, Atsuko Hiura
Publikováno v:
Palliative Care Research. 9:125-130
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 3 (2012)
Frontiers in Endocrinology, Vol 3 (2012)
Increasing evidence indicates that endoplasmic reticulum stress (ER stress) is involved in the development of metabolic syndrome. However, pharmacological treatments targeting ER stress are not well understood. In the present study, we found that flu
Autor:
Chie Hashimoto, Tsuyoshi Miyahara, Koichiro Ozawa, Toru Hosoi, Michiko Yoshii, Suguru Matsuo, Miyako Sasaki
Publikováno v:
Molecular pharmacology. 74(6)
Leptin is an important circulating signal for inhibiting food intake and body weight gain. In recent years, "leptin resistance" has been considered to be one of the main causes of obesity. However, the detailed mechanisms of leptin resistance are poo