Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Tsuyoshi Hirashima"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/1fd29d48e09e4a35b5056159847fc117
Autor:
Shinji Kumegawa, Gen Yamada, Daiki Hashimoto, Tsuyoshi Hirashima, Mizuki Kajimoto, Kyoichi Isono, Kota Fujimoto, Kentaro Suzuki, Kazuhisa Uemura, Masatsugu Ema, Shinichi Asamura
Publikováno v:
Biological Procedures Online, Vol 23, Iss 1, Pp 1-13 (2021)
Abstract Background Because of the high frequency of chronic edema formation in the current “aged” society, analyses and detailed observation of post-surgical edema are getting more required. Post-surgical examination of the dynamic vasculature i
Externí odkaz:
https://doaj.org/article/af8f1e4444c94d0c8ba9c8e7fb2d3947
Autor:
Kota Fujimoto, Daiki Hashimoto, Kenichi Kashimada, Shinji Kumegawa, Yuko Ueda, Taiju Hyuga, Tsuyoshi Hirashima, Norimitsu Inoue, Kentaro Suzuki, Isao Hara, Shinichi Asamura, Gen Yamada
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Erection is an essential process which requires the male penis for copulation. This copulatory process depends on the vascular dynamic regulation of the penis. The corpus cavernosum (CC) in the upper (dorsal) part of the penis plays a major role in r
Externí odkaz:
https://doaj.org/article/13c874efe2b04a36b0ab4b6e0a027f84
Autor:
Hiroshi Ichise, Shoko Tsukamoto, Tsuyoshi Hirashima, Yoshinobu Konishi, Choji Oki, Shinya Tsukiji, Satoshi Iwano, Atsushi Miyawaki, Kenta Sumiyama, Kenta Terai, Michiyuki Matsuda
Publikováno v:
eLife, Vol 11 (2022)
Natural killer (NK) cells lyse invading tumor cells to limit metastatic growth in the lung, but how some cancers evade this host protective mechanism to establish a growing lesion is unknown. Here, we have combined ultra-sensitive bioluminescence ima
Externí odkaz:
https://doaj.org/article/0181e79d5876476faaf234e34d7941c6
Autor:
Tsuyoshi Hirashima
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
All living tissues and organs have their respective sizes, critical to various biological functions, such as development, growth, and homeostasis. As tissues and organs generally converge to a certain size, intrinsic regulatory mechanisms may be invo
Externí odkaz:
https://doaj.org/article/1826c26d451143fcbcedcf5e1df4bb1d
Publikováno v:
Royal Society Open Science, Vol 8, Iss 12 (2021)
The bending of epithelial tubes is a fundamental process in organ morphogenesis, driven by various multicellular behaviours. The cochlea in the mammalian inner ear is a representative example of spiral tissue architecture where the continuous bending
Externí odkaz:
https://doaj.org/article/fa05f8f517fc4229821fd719f6497dc1
Publikováno v:
eLife, Vol 10 (2021)
A notable example of spiral architecture in organs is the mammalian cochlear duct, where the morphology is critical for hearing function. Genetic studies have revealed necessary signaling molecules, but it remains unclear how cellular dynamics genera
Externí odkaz:
https://doaj.org/article/d4d9d98125ec4bba99ffc6f13a7813dc
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Tracheal cartilage provides architectural integrity to the respiratory airway, and defects in this structure during embryonic development cause severe congenital anomalies. Previous genetic studies have revealed genes that are critical for the develo
Externí odkaz:
https://doaj.org/article/8f27d520ee274b9aba9a99919c3c1aa4
Autor:
Tsuyoshi Hirashima
Publikováno v:
Bio-Protocol, Vol 10, Iss 15 (2020)
Cells inside the body are subjected to various mechanical stress, such as stretch or compression provided by surrounding cells, shear stresses by blood or lymph flows, and normal stresses by luminal liquids. Force loading to the biological tissues is
Externí odkaz:
https://doaj.org/article/eb3670df44a24a50859892e52d7a4266
Autor:
Anneliis Ihermann-Hella, Tsuyoshi Hirashima, Jussi Kupari, Kristen Kurtzeborn, Hao Li, Hyuk Nam Kwon, Cristina Cebrian, Abdul Soofi, Arvydas Dapkunas, Ilkka Miinalainen, Gregory R. Dressler, Michiyuki Matsuda, Satu Kuure
Publikováno v:
Stem Cell Reports, Vol 11, Iss 4, Pp 912-928 (2018)
Summary: The in vivo niche and basic cellular properties of nephron progenitors are poorly described. Here we studied the cellular organization and function of the MAPK/ERK pathway in nephron progenitors. Live-imaging of ERK activity by a Förster re
Externí odkaz:
https://doaj.org/article/10e4f35dd807468285ed6280c1c407db