Zobrazeno 1 - 10
of 451
pro vyhledávání: '"Tsuyoshi Goto"'
Autor:
Yusuke Komiya, Yuka Sakazaki, Tsuyoshi Goto, Fuminori Kawabata, Takahiro Suzuki, Yusuke Sato, Shoko Sawano, Mako Nakamura, Ryuichi Tatsumi, Yoshihide Ikeuchi, Keizo Arihara, Wataru Mizunoya
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109816- (2024)
Summary: Muscle fiber type composition (% slow-twitch and % fast-twitch fibers) is associated with metabolism, with increased slow-twitch fibers alleviating metabolic disorders. Previously, we reported that dietary fish oil intake induced a muscle fi
Externí odkaz:
https://doaj.org/article/d7c179064f044c83a28d3c05de50b36c
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Nutrient excess, such as the intake of a high-fat diet, reduces hypothalamic responses to exogenously administered leptin and induces dietary obesity; however, orally active components that attenuate neural leptin dysregulation have yet to b
Externí odkaz:
https://doaj.org/article/dcb6c3b6c8134408ae12647e3206cc23
Autor:
Jungin Kwon, Yu-Sheng Yeh, Satoko Kawarasaki, Hiroto Minamino, Yoshihito Fujita, Yuko Okamatsu-Ogura, Haruya Takahashi, Wataru Nomura, Shigenobu Matsumura, Rina Yu, Kazuhiro Kimura, Masayuki Saito, Nobuya Inagaki, Kazuo Inoue, Teruo Kawada, Tsuyoshi Goto
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106161- (2023)
Summary: The high thermogenic activity of brown adipose tissue (BAT) has received considerable attention. Here, we demonstrated the role of the mevalonate (MVA) biosynthesis pathway in the regulation of brown adipocyte development and survival. The i
Externí odkaz:
https://doaj.org/article/006dbc30a5a543a881cdd512485a53ca
Autor:
Jin Tanaka, Fuka Ishikawa, Tomoki Jinno, Motoki Miyakita, Haruka Miyamori, Tsutomu Sasaki, Takumi Yokokawa, Tsuyoshi Goto, Kazuo Inoue, Shigenobu Matsumura
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
cAMP responsive element binding protein (CREB)-regulated transcription coactivators (CRTCs) regulate gene transcription in response to an increase in intracellular cAMP or Ca2+ levels. To date, three isoforms of CRTC have been identified in mammals.
Externí odkaz:
https://doaj.org/article/ced331e0a2d24f0797bb1be183d28e93
Autor:
Shinsuke Mohri, Haruya Takahashi, Maiko Sakai, Naoko Waki, Shingo Takahashi, Koichi Aizawa, Hiroyuki Suganuma, Takeshi Ara, Tatsuya Sugawara, Daisuke Shibata, Yasuki Matsumura, Tsuyoshi Goto, Teruo Kawada
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0267248 (2022)
Adiponectin, an adipokine, regulates glucose metabolism and insulin sensitivity through the adiponectin receptor (AdipoR). In this study, we searched for metabolites that activate the adiponectin signaling pathway from tomato (Solanum lycopersicu). M
Externí odkaz:
https://doaj.org/article/25bed657e5ae4bbe9427179e1958fe54
Publikováno v:
Biochemistry and Biophysics Reports, Vol 28, Iss , Pp 101127- (2021)
Methylglyoxal (MG) is a metabolite derived from glycolysis whose levels in the blood and tissues of patients with diabetes are higher than those of healthy individuals, suggesting that MG is associated with the development of diabetic complications.
Externí odkaz:
https://doaj.org/article/c35bd20efc9c4d6587c4d0a26bdc8ee2
Autor:
Tsuyoshi Goto, Toshinori Sakai, Kosuke Sugiura, Hiroaki Manabe, Masatoshi Morimoto, Fumitake Tezuka, Kazuta Yamashita, Yoichiro Takata, Takashi Chikawa, Shinsuke Katoh, Koichi Sairyo
Publikováno v:
Spine Surgery and Related Research, Vol 3, Iss 2, Pp 146-150 (2019)
Introduction: In past biomechanical studies, repetitive motion of lumbar extension, rotation, or a combination of both, frequently seen in batting or pitching practice in baseball, shooting practice in soccer, and spiking practice in volleyball, have
Externí odkaz:
https://doaj.org/article/f2461c5b639544ab99333da24c5f33a5
Autor:
Kohei Kiriyama, Tsuyoshi Goto, Hirotaka Yamamoto, Takeshi Ara, Haruya Takahashi, Huei-Fen Jheng, Wataru Nomura, Hiroyasu Inoue, Rieko Nakata, Teruo Kawada
Publikováno v:
Journal of Functional Foods, Vol 54, Iss , Pp 529-535 (2019)
The onset of sleep has been reported to be accompanied by a decline in the core body temperature (CBT) at the onset of night. The stimulation of hepatic FGF21 by PPARα agonist influences the central nervous system and decreases the CBT. The present
Externí odkaz:
https://doaj.org/article/1b29fe8d1e864647aba43f2dfeac4719
Autor:
Masatoshi Morimoto, Toshinori Sakai, Tsuyoshi Goto, Kosuke Sugiura, Hiroaki Manabe, Fumitake Tezuka, Kazuta Yamashita, Yoichiro Takata, Takashi Chikawa, Koichi Sairyo
Publikováno v:
Spine Surgery and Related Research, Vol 3, Iss 1, Pp 49-53 (2019)
Introduction: Recent advances in diagnostic imaging, such as computed tomography (CT) and magnetic resonance imaging (MRI), have allowed early diagnosis of lumbar spondylolysis (LS). However, few outpatient clinics are equipped with such imaging appa
Externí odkaz:
https://doaj.org/article/c7c62a9f4cb04c3b911ede707fb4c67d
Autor:
Toshinori Sakai, Tsuyoshi Goto, Kosuke Sugiura, Hiroaki Manabe, Fumitake Tezuka, Kazuta Yamashita, Yoichiro Takata, Takashi Chikawa, Koichi Sairyo
Publikováno v:
Spine Surgery and Related Research, Vol 3, Iss 1, Pp 67-70 (2019)
Introduction: Although there has been a dramatic improvement in the outcomes of conservative treatment to achieve bony healing due to advances in diagnostic and therapeutic tools, in some patients, the results continue to be unfavorable. The purpose
Externí odkaz:
https://doaj.org/article/788bc0f707714910a5606046e3639b09