Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Tsuyoshi ARAI"'
Publikováno v:
ACS Omega, Vol 6, Iss 33, Pp 21809-21818 (2021)
Externí odkaz:
https://doaj.org/article/aa147ae98b6b430cb74fd103be88926d
Autor:
Shoji Hashimoto, Kazuyuki Yoshizaki, Kazuko Uno, Heita Kitajima, Tsuyoshi Arai, Yoshitaka Tamura, Hiroshi Morishita, Hiroto Matsuoka, Yuki Han, Seijiro Minamoto, Tomonori Hirashima, Tomoki Yamada, Yozo Kashiwa, Makoto Kameda, Seiji Yamaguchi, Yasunari Tsuchihashi, Mitsuhiro Iwahashi, Emi Nakayama, Tatsuo Shioda, Takayuki Nagai, Toshio Tanaka
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background and Aim: Tocilizumab, a humanized anti-IL-6 receptor antibody, has been used to treat severely to critically ill patients with COVID-19. A living systematic review with meta-analysis of recent RCTs indicates that the combination therapy of
Externí odkaz:
https://doaj.org/article/59df56ed85ed4c4b8f36715d9ba6fd85
Publikováno v:
Journal of MMIJ, Vol 133, Iss 5, Pp 84-91 (2017)
Although solvent extraction has been used in the recovery of rare metals from urban mines, some challenges remain. For example, large amounts of organic solvent are required for Pd (II) separation owing to the slow extraction kinetics of dihexylsulfi
Externí odkaz:
https://doaj.org/article/391768379f6147418ccc28e29519097d
Publikováno v:
Journal of MMIJ, Vol 132, Iss 5, Pp 89-95 (2016)
Mutual separation of rare earth ions is very difficult because of their similar chemical properties. In this study, extraction of Nd (III), Dy (III), and Pr (III) from hydrochloric acid solution and their back extraction have been investigated using
Externí odkaz:
https://doaj.org/article/cc2a6d16c4a748b9a1472d272ad65436
Autor:
Tadashi Akuzawa, Seong-Yun Kim, Masahiko Kubota, Hao Wu, Sou Watanabe, Yuchi Sano, Masayuki Takeuchi, Tsuyoshi Arai
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 331:5851-5858
Autor:
Hidehito Kotani, Shinji Mizuarai, Takashi Yoshizumi, Takeshi Sagara, Toshihiro Sakamoto, Hiroharu Arakawa, Takumi Sakai, Jian Jiang, Tadahiro Nambu, Hiroko Oki, Kazuhiro Fukasawa, Ikuko Takahashi-Suzuki, Hiraku Itadani, Kazunori Yamanaka, Junko Ohtani, Naoki Kaneko, Toshifumi Kimura, Makiko Kobayashi, Toshihide Nishibata, Tsuyoshi Arai, Megumu Okada, Yoshikazu Iwasawa, Hiroshi Hirai
Supplementary Figure 4 from Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fbd4990659e663b7dccb7e40258433
https://doi.org/10.1158/1535-7163.22486068
https://doi.org/10.1158/1535-7163.22486068
Autor:
Hidehito Kotani, Shinji Mizuarai, Takashi Yoshizumi, Takeshi Sagara, Toshihiro Sakamoto, Hiroharu Arakawa, Takumi Sakai, Jian Jiang, Tadahiro Nambu, Hiroko Oki, Kazuhiro Fukasawa, Ikuko Takahashi-Suzuki, Hiraku Itadani, Kazunori Yamanaka, Junko Ohtani, Naoki Kaneko, Toshifumi Kimura, Makiko Kobayashi, Toshihide Nishibata, Tsuyoshi Arai, Megumu Okada, Yoshikazu Iwasawa, Hiroshi Hirai
Wee1 is a tyrosine kinase that phosphorylates and inactivates CDC2 and is involved in G2 checkpoint signaling. Because p53 is a key regulator in the G1 checkpoint, p53-deficient tumors rely only on the G2 checkpoint after DNA damage. Hence, such tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6083f36a3d2a471a2a2ebf46afa829f9
https://doi.org/10.1158/1535-7163.c.6532227.v1
https://doi.org/10.1158/1535-7163.c.6532227.v1
Autor:
Hidehito Kotani, Shinji Mizuarai, Takashi Yoshizumi, Takeshi Sagara, Toshihiro Sakamoto, Hiroharu Arakawa, Takumi Sakai, Jian Jiang, Tadahiro Nambu, Hiroko Oki, Kazuhiro Fukasawa, Ikuko Takahashi-Suzuki, Hiraku Itadani, Kazunori Yamanaka, Junko Ohtani, Naoki Kaneko, Toshifumi Kimura, Makiko Kobayashi, Toshihide Nishibata, Tsuyoshi Arai, Megumu Okada, Yoshikazu Iwasawa, Hiroshi Hirai
Supplementary Figure 3 from Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f3febe721d3504881be88ebdf1890e
https://doi.org/10.1158/1535-7163.22486071
https://doi.org/10.1158/1535-7163.22486071
Autor:
Hidehito Kotani, Shinji Mizuarai, Takashi Yoshizumi, Takeshi Sagara, Toshihiro Sakamoto, Hiroharu Arakawa, Takumi Sakai, Jian Jiang, Tadahiro Nambu, Hiroko Oki, Kazuhiro Fukasawa, Ikuko Takahashi-Suzuki, Hiraku Itadani, Kazunori Yamanaka, Junko Ohtani, Naoki Kaneko, Toshifumi Kimura, Makiko Kobayashi, Toshihide Nishibata, Tsuyoshi Arai, Megumu Okada, Yoshikazu Iwasawa, Hiroshi Hirai
Supplementary Figure 1 from Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fe199219c306c270d9d95973603ade
https://doi.org/10.1158/1535-7163.22486077
https://doi.org/10.1158/1535-7163.22486077
Autor:
Hidehito Kotani, Shinji Mizuarai, Takashi Yoshizumi, Takeshi Sagara, Toshihiro Sakamoto, Hiroharu Arakawa, Takumi Sakai, Jian Jiang, Tadahiro Nambu, Hiroko Oki, Kazuhiro Fukasawa, Ikuko Takahashi-Suzuki, Hiraku Itadani, Kazunori Yamanaka, Junko Ohtani, Naoki Kaneko, Toshifumi Kimura, Makiko Kobayashi, Toshihide Nishibata, Tsuyoshi Arai, Megumu Okada, Yoshikazu Iwasawa, Hiroshi Hirai
Supplementary Figure 2 from Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c548c563bdee1d537f11e9305fc523c6
https://doi.org/10.1158/1535-7163.22486074.v1
https://doi.org/10.1158/1535-7163.22486074.v1