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pro vyhledávání: '"Tsuyoshi, Ish"'
Autor:
Tsuyoshi, Ish, Hiroshi, Sootome, Alastair J, King, Mikiya, Suda, Nobuhiro, Noro, Keizo, Yamashita, Takato, Noumi, Tsuyoshi, Ishii
Publikováno v:
Journal of biomolecular screening. 12(6)
Checkpoint kinase 1 (Chk1), a serine/threonine kinase, plays an important role in DNA damage checkpoint control and is an attractive target for cancer treatment. To develop a Chk1-specific cell-based assay, stable clones were established in which Chk
Autor:
Tsuyoshi, Ish, Hiroshi, Sootome, Yukiko, Yagi, Keizo, Yamashita, Takato, Noumi, Nobuhiro, Noro, Tsuyoshi, Ishii
Publikováno v:
Journal of biomolecular screening. 12(6)
The Ras/Raf signaling pathway has been recognized as an important process in cancer biology. Recently, activating mutations in the BRAF gene were reported to be present in approximately 66% of malignant melanomas as well as other malignancies such as