Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Tsuyako Tatematsu"'
Autor:
Kana Ozaki, Daisuke Kato, Ako Ikegami, Akari Hashimoto, Shouta Sugio, Zhongtian Guo, Midori Shibushita, Tsuyako Tatematsu, Koichiro Haruwaka, Andrew J. Moorhouse, Hideto Yamada, Hiroaki Wake
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-19 (2020)
Abstract Maternal infection or inflammation causes abnormalities in brain development associated with subsequent cognitive impairment and in an increased susceptibility to schizophrenia and autism spectrum disorders. Maternal immune activation (MIA)
Externí odkaz:
https://doaj.org/article/979f3c83c7a34bd2aeab127d90ed220a
Autor:
Yuta Ogasawara, Jinglei Cheng, Tsuyako Tatematsu, Misaki Uchida, Omi Murase, Shogo Yoshikawa, Yuki Ohsaki, Toyoshi Fujimoto
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The source of phospholipids to generate autophagosomal membranes, particularly after prolonged starvation, is not well characterized. Here, the authors show that CCTβ3, the rate limiting enzyme in phosphatidylcholine synthesis, is activated on lipid
Externí odkaz:
https://doaj.org/article/01aa050b4596409a8597336a1d223531
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
The origin and physiological significance of lipid droplets (LDs) in the nucleus is not clear. Here authors show that nucleoplasmic LDs in hepatocytes are derived from apolipoprotein B (ApoB)-free lumenal LDs and constitute a feedback mechanism to re
Externí odkaz:
https://doaj.org/article/98f83579d492448e8f406580e20eef6d
Autor:
Takuma Tsuji, Megumi Fujimoto, Tsuyako Tatematsu, Jinglei Cheng, Minami Orii, Sho Takatori, Toyoshi Fujimoto
Publikováno v:
eLife, Vol 6 (2017)
Niemann-Pick type C is a storage disease caused by dysfunction of NPC proteins, which transport cholesterol from the lumen of lysosomes to the limiting membrane of that compartment. Using freeze fracture electron microscopy, we show here that the yea
Externí odkaz:
https://doaj.org/article/5b8ac16b97684bf7a268e3dd85ae1c07
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained errors in the Abstract and Introduction, whereby CCTα was incorrectly defined as an abbreviation of CDP-choline diacylglycerol phosphotransferase α, instead of CTP:phosphocholine cytidylyltransferase
Externí odkaz:
https://doaj.org/article/f37b9e5ddd804b0aba5c33bd03103a55
Autor:
Michitaka Suzuki, Yuki Ohsaki, Tsuyako Tatematsu, Yuki Shinohara, Takashi Maeda, Jinglei Cheng, Toyoshi Fujimoto
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42379 (2012)
Lipid droplets (LDs) in non-adipocytes contain triglycerides (TG) and cholesterol esters (CE) in variable ratios. TG-rich LDs are generated when unsaturated fatty acids are administered, but the conditions that induce CE-rich LD formation are less we
Externí odkaz:
https://doaj.org/article/dbb4a9b77a0142e38b138a29cdeeab4b
Autor:
Toyoshi Fujimoto, Yuki Ohsaki, Shogo Yoshikawa, Misaki Uchida, Jinglei Cheng, Omi Murase, Yuta Ogasawara, Tsuyako Tatematsu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
Macroautophagy initiates by formation of isolation membranes, but the source of phospholipids for the membrane biogenesis remains elusive. Here, we show that autophagic membranes incorporate newly synthesized phosphatidylcholine, and that CTP:phospho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9f2f30cc0a82a38bb17c4670c11190
https://doaj.org/article/01aa050b4596409a8597336a1d223531
https://doaj.org/article/01aa050b4596409a8597336a1d223531
Autor:
Zhongtian Guo, Shouta Sugio, Hideto Yamada, Ako Ikegami, Akari Hashimoto, Kana Ozaki, Tsuyako Tatematsu, Midori Shibushita, Daisuke Kato, Andrew J. Moorhouse, Hiroaki Wake, Koichiro Haruwaka
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-19 (2020)
Scientific Reports
Scientific Reports
Maternal infection or inflammation causes abnormalities in brain development associated with subsequent cognitive impairment and in an increased susceptibility to schizophrenia and autism spectrum disorders. Maternal immune activation (MIA) and incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c6bc5795db32a984143650c0b88d40
https://doi.org/10.1038/s41598-020-78294-2
https://doi.org/10.1038/s41598-020-78294-2
Autor:
Asami Maeda, Jinglei Cheng, Toyoshi Fujimoto, Yuki Ohsaki, Kamil Sołtysik, Tsuyako Tatematsu, Shin-ya Morita
Publikováno v:
The Journal of Cell Biology
Sołtysik et al. show that the inner nuclear membrane of nonhepatocytes harbors triglyceride synthesis enzymes and generates nuclear lipid droplets (LDs). Seipin knockdown increases nuclear LDs through upregulating lipin-1β transcription and increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be1c6f82d1325e4833ee27fba42958c
http://europepmc.org/articles/PMC7737703
http://europepmc.org/articles/PMC7737703
Autor:
Toyoshi Fujimoto, Takuma Tsuji, Akikazu Fujita, Hiroyuki Arai, Tomohiko Taguchi, Jinglei Cheng, Sayuri Gyobu, Katsumori Segawa, Hiroki Kamikawa, Tsuyako Tatematsu, Shigekazu Nagata, Aoi Ebata
TMEM16K, a membrane protein carrying 10 transmembrane regions, has phospholipid scramblase activity. TMEM16K is localized to intracellular membranes, but whether it actually scrambles phospholipids inside cells has not been demonstrated, due to techn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c131f6db62f893490469cb4c3330a3
https://europepmc.org/articles/PMC6613088/
https://europepmc.org/articles/PMC6613088/
