Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Tsutomu Yoshihara"'
Autor:
Noboru Misawa, Masaru Matsumoto, Momoko Tsuda, Shigeki Tamura, Tsutomu Yoshihara, Keiichi Ashikari, Takaomi Kessoku, Hidenori Ohkubo, Takuma Higurashi, Hiromi Sanada, Mototsugu Kato, Atsushi Nakajima
Publikováno v:
Journal of the Anus, Rectum and Colon, Vol 8, Iss 2, Pp 126-131 (2024)
Objectives: Chronic constipation is a common gastrointestinal disorder, and management is crucial. Computed tomography (CT) is useful for evaluating rectal fecal mass but limited owing to radiation exposure, cost, and inaccessibility at certain facil
Externí odkaz:
https://doaj.org/article/f67cbb51bae341cab2a69730f47cb003
Autor:
Atsushi Yamamoto, Takaomi Kessoku, Tomoki Ogata, Tsumugi Jono, Kota Takahashi, Kosuke Tanaka, Ko Suzuki, Yuma Takeda, Anna Ozaki, Yuki Kasai, Naoki Okubo, Michihiro Iwaki, Takashi Kobayashi, Noboru Misawa, Tsutomu Yoshihara, Akihiro Suzuki, Akiko Fuyuki, Sho Hasegawa, Kento Imajo, Noritoshi Kobayashi, Masaru Matsumoto, Nao Tamai, Hiromi Sanada, Shunsuke Oyamada, Yasushi Ichikawa, Atsushi Nakajima
Publikováno v:
Diagnostics, Vol 14, Iss 15, p 1626 (2024)
Although handheld ultrasound devices (HUDs) are commonplace, their ability to diagnose fecal retention (FR) remains unclear. This prospective observational study examined HUDs’ usefulness in diagnosing FR in patients with constipation in a palliati
Externí odkaz:
https://doaj.org/article/bb311d6b483e44069531ec6d5ebda3f7
Autor:
Tomohiro Takatsu, Noboru Misawa, Tsutomu Yoshihara, Keiichi Ashikari, Takaomi Kessoku, Hidenori Ohkubo, Kunihiro Hosono, Masato Yoneda, Satoru Saito, Atsushi Nakajima, Takuma Higurashi
Publikováno v:
JGH Open, Vol 7, Iss 8, Pp 559-566 (2023)
Abstract Background and Aim Ischemic colitis (IC) is a benign disease associated with acute lower gastrointestinal bleeding and frequent recurrence. While several studies have investigated risk factors for IC onset, few have assessed the risk factors
Externí odkaz:
https://doaj.org/article/e382d809f2464032b8ae05e16db4c1b2
Autor:
Yumi Shimomura, Yutaka Sugi, Aiko Kume, Wataru Tanaka, Tsutomu Yoshihara, Tetsuya Matsuura, Yasuhiko Komiya, Yusuke Ogata, Wataru Suda, Masahira Hattori, Takuma Higurashi, Atsushi Nakajima, Mitsuharu Matsumoto
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Fusobacterium nucleatum is associated with colorectal cancer (CRC), and identical F. nucleatum strains seemed to be detected in 75% of patients who exhibited the presence of F. nucleatum in both CRC and saliva samples in our previous study;
Externí odkaz:
https://doaj.org/article/5ba4a3890aa94dfaa129a6f068a4e595
Autor:
Tsutomu Yoshihara, Mitomu Kioi, Junichi Baba, Haruki Usuda, Takaomi Kessoku, Michihiro Iwaki, Tomohiro Takatsu, Noboru Misawa, Keiichi Ashikari, Tetsuya Matsuura, Akiko Fuyuki, Hidenori Ohkubo, Mitsuharu Matsumoto, Koichiro Wada, Atsushi Nakajima, Takuma Higurashi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Fusobacterium nucleatum is associated with the progression of colorectal cancer. Thus, the possibility of preventing colorectal cancer or its progression by targeting F. nucleatum has been explored. As F. nucleatum is associated with periodo
Externí odkaz:
https://doaj.org/article/0a17b49f25c6483d9ddc513540e11243
Autor:
Tsutomu Yoshihara, Takaomi Kessoku, Tomohiro Takatsu, Noboru Misawa, Keiichi Ashikari, Akiko Fuyuki, Hidenori Ohkubo, Takuma Higurashi, Michihiro Iwaki, Takeo Kurihashi, Machiko Nakatogawa, Koji Yamamoto, Izuru Terada, Yusuke Tanaka, Atsushi Nakajima
Publikováno v:
Contemporary Clinical Trials Communications, Vol 30, Iss , Pp 101019- (2022)
Background: Chronic constipation leads to poor quality of life, and treatment remains unsatisfactory for patients. In Japan, magnesium oxide has been commonly used as the first choice of treatment for constipation; however, there are some cases of lo
Externí odkaz:
https://doaj.org/article/d145b1d9d0cb49f5adc230e19522f7c4
Autor:
Atsushi Yamamoto, Takaomi Kessoku, Kosuke Tanaka, Kota Takahashi, Yuki Kasai, Anna Ozaki, Michihiro Iwaki, Takashi Kobayashi, Tsutomu Yoshihara, Noboru Misawa, Kanji Ohkuma, Akiko Fuyuki, Takuma Higurashi, Kunihiro Hosono, Masato Yoneda, Tomoyuki Iwasaki, Takeo Kurihashi, Machiko Nakatogawa, Ayao Suzuki, Masataka Taguri, Shunsuke Oyamada, Keisuke Ariyoshi, Noritoshi Kobayashi, Yasushi Ichikawa, Atsushi Nakajima
Publikováno v:
Contemporary Clinical Trials Communications, Vol 28, Iss , Pp 100958- (2022)
Background: Approximately 60% of patients with chronic constipation (CC) have a significantly higher rate of loss of defecation desire (LODD). Bile acids are expected to have a restorative effect on defecation desire (DD) because they lower the recta
Externí odkaz:
https://doaj.org/article/07d98197f50b47d384147d049544ecea
Autor:
Takuma Higurashi, Jun Arimoto, Atsushi Nakajima, Keisuke Ariyoshi, Shunsuke Oyamada, Masataka Taguri, Masato Yoneda, Takaomi Kessoku, Takashi Kobayashi, Anna Ozaki, Tomoyuki Iwasaki, Takeo Kurihashi, Michihiro Iwaki, Kunihiro Hosono, Eiji Sakai, Kosuke Tanaka, Atsushi Yamamoto, Kota Takahashi, Yuki Kasai, Tsutomu Yoshihara, Noboru Misawa, Takayuki Kato, Akiko Fuyuki, Hideyuki Chiba, Machiko Nakatogawa, Ayao Suzuki, Noritoshi Kobayashi, Yasushi Ichikawa
Publikováno v:
BMJ Open, Vol 12, Iss 5 (2022)
Introduction Chronic constipation (CC) is a functional disorder that negatively impacts the quality of life of patients. This is a protocol for a multicentre, 12-week, randomised, double-blind, placebo-controlled study to test the efficacy and safety
Externí odkaz:
https://doaj.org/article/5c891ed06a8f49059d851fd757461958
Autor:
Takuma Higurashi, Jun Arimoto, Keiichi Ashikari, Tomohiro Takatsu, Noboru Misawa, Tsutomu Yoshihara, Tetsuya Matsuura, Akiko Fuyuki, Hidenori Ohkubo, Atsushi Nakajima
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-7 (2020)
Abstract Background The incidence and mortality rates of colorectal cancer (CRC) continue to increase worldwide. Therefore, new preventive strategies are needed to lower the burden of this disease. Previous studies reported that aspirin could suppres
Externí odkaz:
https://doaj.org/article/30804816035c4195b23ebd164ec576f6
Autor:
Tsutomu Yoshihara, Yosuke Oikawa, Takayuki Kato, Takaomi Kessoku, Takashi Kobayashi, Shingo Kato, Noboru Misawa, Keiichi Ashikari, Akiko Fuyuki, Hidenori Ohkubo, Takuma Higurashi, Yoko Tateishi, Yoshiki Tanaka, Shunji Nakajima, Hiroshi Ohno, Koichiro Wada, Atsushi Nakajima
Publikováno v:
Gut Microbes, Vol 11, Iss 5, Pp 1385-1404 (2020)
Background Proton pump inhibitors (PPIs) can alleviate upper gastrointestinal injury but paradoxically exacerbate aspirin (ASA)-induced small intestine injury. In this study, our goal was to simulate this exacerbation by developing an appropriate ani
Externí odkaz:
https://doaj.org/article/501133c54fea4df69cb98f96bd953809