Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tsutomu Yamaki"'
Autor:
Yusuke Kamiya, Tsutomu Yamaki, Shigehiro Omori, Masaki Uchida, Kazuo Ohtake, Mitsutoshi Kimura, Hiroshi Yamazaki, Hideshi Natsume
Publikováno v:
Pharmaceuticals, Vol 11, Iss 1, p 9 (2018)
We reported that the introduction of polyethylene glycol (PEG) to poly-l-ornithine (PLO), which is an homopolymeric basic amino acid having absorption-enhancement ability, prolonged retention time in an in vitro inclined plate test, probably due to a
Externí odkaz:
https://doaj.org/article/611ee6c7d5da4839be1e028cc9817a12
Publikováno v:
Journal of Oleo Science; 2024, Vol. 73 Issue 4, p611-618, 8p
Publikováno v:
Chemical Communications. 59:5114-5117
Herein, we report anomalous glucose (Glc)-responsive gelation/solation in 3-aminophenylboronic acid-modified hyaluronic acid. With 5-20 mM Glc, gelation occurred, resulting in the formation of crosslinks via Glc, which could reversibly bind to the tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffbb99811a83494781611bab59e81ae0
https://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-d3cc01020a
https://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-d3cc01020a
Autor:
Yoshiro Tokizono, Narushi Suda, Tsutomu Yamaki, Ryota Aritomo, Aaron D. Beattie, Masahito Nanamori, Wataru Saito, Naohiko Hirota, Takehiro Hoki
Publikováno v:
Breeding Science
Various types of malt quality profiles have been investigated to benefit the North American brewing industry. Herein, we report the development and brewing quality of the hulled, two-row malting barley (Hordeum vulgare L.) variety 'CDC Goldstar' lack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5428f00fcad4b269364f88b40ee36e2
http://europepmc.org/articles/PMC8329874
http://europepmc.org/articles/PMC8329874
Publikováno v:
Colloids and Surfaces A: Physicochemical and Engineering Aspects. 648:129418
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30d0ee77a1a4fc40b64a0818380dfedd
https://doi.org/10.1016/j.colsurfa.2022.129418
https://doi.org/10.1016/j.colsurfa.2022.129418
Autor:
Masaki Uchida, Kazuo Ohtake, Shigehiro Omori, Yusuke Kamiya, Mitsutoshi Kimura, Hideshi Natsume, Tsutomu Yamaki
Publikováno v:
Biologicalpharmaceutical bulletin. 42(1)
The transnasal route for the delivery of water-soluble macromolecules, such as bioactive peptides and proteins, has attracted interest, although the use of permeation enhancers is required due to the poor permeabilities of these macromolecules across
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85a82e7d04b49f71248cbb740205dd6
https://pubmed.ncbi.nlm.nih.gov/30606986
https://pubmed.ncbi.nlm.nih.gov/30606986
Autor:
Masaki Uchida, Hiroyuki Uchida, Mitsutoshi Kimura, Kaho Ogawa, Tsutomu Yamaki, Mari Okazaki, Hirokazu Matsuzaki, Hideshi Natsume
Publikováno v:
International Journal of Pharmaceutics. 594:120046
Acetaminophen, a central antipyretic and analgesic drug, is one of the most commonly used drugs among individuals of all ages throughout the world. This study pharmacokinetically and pharmacodynamically investigated the transport of acetaminophen to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd53d78a9560b47327ecd633dc0e625
https://doi.org/10.1016/j.ijpharm.2020.120046
https://doi.org/10.1016/j.ijpharm.2020.120046
Autor:
Hideo Ueda, Tsutomu Yamaki, Hideshi Natsume, Kazuo Ohtake, Jun Kobayashi, Yasunori Morimoto, Hiroyuki Uchida, Tomomi Hatanaka, Ryo Kawashima, Masaki Uchida
Publikováno v:
Biological and Pharmaceutical Bulletin. 39(3):329-335
A novel system for delivering recombinant human growth hormone (rhGH) that is noninvasive and has a simple method of administration is strongly desired to improve the compliance of children. The aim of this study was to investigate the potential for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac0f638d7ad0aa89ea1cdd96c15fedb
http://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-bpb.b15-00657
http://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-bpb.b15-00657
Autor:
Yusuke Kuwahara, Kazuo Ohtake, Masahiko Ogihara, Tsutomu Yamaki, Hiroyuki Uchida, Masaki Uchida, Jun Kobayashi, Yasunori Morimoto, Hideshi Natsume, Yohei Shimazaki, Mitsutoshi Kimura
Publikováno v:
Biological and Pharmaceutical Bulletin. 36:496-500
We have already reported that poly-L-arginine (PLA) remarkably enhanced the in vivo nasal absorption of hydrophilic macromolecules without producing any significant epithelial damage in rats. In the present study, we examined whether PLA could enhanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6c462b7f5e34aac88e16434c04a813c
https://doi.org/10.1248/bpb.b12-00974
https://doi.org/10.1248/bpb.b12-00974
Autor:
Hiroyuki Uchida, Kazuhiko Juni, Tsutomu Yamaki, Jun Kobayashi, Hideshi Natsume, Shinji Ohshima, Keiko Ichikawa, Kazuo Ohtake, Masaki Uchida, Yasunori Morimoto
Publikováno v:
Biological and Pharmaceutical Bulletin. 36:432-441
We investigated whether poly-L-arginine (PLA) enhances the paracellular permeability of the Caco-2 monolayer to hydrophilic macromolecules and clarified the disposition of tight junction (TJ) proteins. The transepithelial electrical resistance (TEER)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de2f7a61a2539aca1cbb063ad3e5bc26
https://doi.org/10.1248/bpb.b12-00878
https://doi.org/10.1248/bpb.b12-00878