Zobrazeno 1 - 10
of 331
pro vyhledávání: '"Tsutomu S"'
Autor:
Daichi Maeda, Yuya Matsue, Nobuyuki Kagiyama, Yudai Fujimoto, Tsutomu Sunayama, Taishi Dotare, Taisuke Nakade, Kentaro Jujo, Kazuya Saito, Kentaro Kamiya, Hiroshi Saito, Yuki Ogasahara, Emi Maekawa, Masaaki Konishi, Takeshi Kitai, Kentaro Iwata, Hiroshi Wada, Masaru Hiki, Takatoshi Kasai, Hirofumi Nagamatsu, Tetsuya Ozawa, Katsuya Izawa, Shuhei Yamamoto, Naoki Aizawa, Kazuki Wakaume, Kazuhiro Oka, Shin‐ichi Momomura, Tohru Minamino
Publikováno v:
ESC Heart Failure, Vol 11, Iss 6, Pp 3723-3731 (2024)
Abstract Aims In heart failure (HF), inflammation is linked to malnutrition and impaired physical function. In this study, we aimed to assess how novel nutritional–inflammatory markers and lymphocyte‐to‐C‐reactive protein ratio (LCR) and scor
Externí odkaz:
https://doaj.org/article/181e348e6b93457c986cf3814197283f
Autor:
Shigenobu Matsumura, Miyu Fujisawa, Mizuki Fujiwara, Houko Okayama, Miona Marutani, Eri Nousou, Tsutomu Sasaki, Naoki Harada
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 12, Pp 597-611 (2024)
Abstract Cyclic adenosine monophosphate‐response element‐binding protein‐1‐regulated transcription coactivator‐1 (CRTC1), a cytoplasmic coactivator that translocates to the nucleus in response to cAMP, is associated with obesity. We previou
Externí odkaz:
https://doaj.org/article/41ef3563745c4d1cb427a714c4bf5f4c
Autor:
Tsutomu Sakurada, Junhui Zhao, Charlotte Tu, Brian Bieber, Melissa Cheetham, Ronald L. Pisoni, Jeffrey Perl, Ken Tsuchiya, Hideki Kawanishi, Jun Minakuchi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Effects of the initial peritoneal dialysis (PD) prescription on clinical outcomes are unknown in Japan. We conducted a cohort study using data from Peritoneal Dialysis Outcomes and Practice Patterns Study. The patients were divided into two
Externí odkaz:
https://doaj.org/article/1ddd1b9fa7a141f5b624fef0967e6a62
Autor:
Tsutomu Sasaki, Sunao Hisada, Hideaki Kanki, Kazuto Nunomura, Bangzhong Lin, Kumiko Nishiyama, Tomohito Kawano, Shigenobu Matsumura, Hideki Mochizuki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Calcium oscillations in primary neuronal cultures and iPSCs have been employed to investigate arrhythmogenicity and epileptogenicity in drug development. Previous studies have demonstrated that Ca2+ influx via NMDA and nicotinic acetylcholin
Externí odkaz:
https://doaj.org/article/9b6e3447e8e248359c5367162194bbbc
Autor:
Yuriko Yamazaki, Tomoka Ito, Seitaro Nakagawa, Takashi Sugihira, Chinami Kurita-Tachibana, Amer E. Villaruz, Kensuke Ishiguro, Barbora Salcman, Shuo Li, Sanami Takada, Naohiro Inohara, Yoko Kusuya, Aki Shibata, Masakazu Tamai, Reika Aoyama, Kanako Inoue, Shota Murata, Kazuyuki Matsushita, Akiko Miyabe, Toshibumi Taniguchi, Hidetoshi Igari, Naruhiko Ishiwada, Masateru Taniguchi, Taka-Aki Nakada, Hiroyuki Matsue, Manabu Fujimoto, Haruka Hishiki, Yoshiteru Osone, Hiromichi Hamada, Naoki Shimojo, Tsutomu Suzuki, Michael Otto, Gabriel Núñez, Hiroki Takahashi, Akiko Takaya, Yuumi Nakamura
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Staphylococcus aureus can cause outbreaks and becomes multi-drug resistant through gene mutations and acquiring resistance genes. However, why S. aureus easily adapts to hospital environments, promoting resistance and recurrent infections, r
Externí odkaz:
https://doaj.org/article/786e7ed982d340fb8bdfc8014ce47951
Autor:
Sunita Maharjan, Howard Gamper, Yuka Yamaki, Thomas Christian, Robert Y. Henley, Nan-Sheng Li, Takeo Suzuki, Tsutomu Suzuki, Joseph A. Piccirilli, Meni Wanunu, Erin Seifert, Douglas C. Wallace, Ya-Ming Hou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Human mitochondrial tRNAs (mt-tRNAs), critical for mitochondrial biogenesis, are frequently associated with pathogenic mutations. These mt-tRNAs have unusual sequence motifs and require post-transcriptional modifications to stabilize their f
Externí odkaz:
https://doaj.org/article/6beaaf5507164908a32932465f77b163
Autor:
Jin Matsuura, Shinichiro Akichika, Fan-Yan Wei, Tsutomu Suzuki, Takahiro Yamamoto, Yuka Watanabe, Leoš Shivaya Valášek, Akitake Mukasa, Kazuhito Tomizawa, Takeshi Chujo
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Human cytoplasmic tRNAs contain dihydrouridine modifications at positions 16 and 17 (D16/D17). The enzyme responsible for D16/D17 formation and its cellular roles remain elusive. Here, we identify DUS1L as the human tRNA D16/D17 writer. DUS1
Externí odkaz:
https://doaj.org/article/62cf225a3782431ea55558721a3f500c
Autor:
Yoshihiko Taniguchi, Akihiro Tamiya, Mitsuo Osuga, Daijiro Harada, Shun-ichi Isa, Keiichi Nakamura, Yasuyuki Mizumori, Tsutomu Shinohara, Hidetoshi Yanai, Katsumi Nakatomi, Masahide Oki, Masahide Mori, Tomohito Kuwako, Koji Yamazaki, Atsuhisa Tamura, Masahiko Ando, Yasuhiro Koh
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-6 (2024)
Abstract Background/Aim For patients treated with osimertinib as first-line therapy, there have been no studies comparing both progression-free survival (PFS) and overall survival (OS) according to performance status (PS). Furthermore, no studies hav
Externí odkaz:
https://doaj.org/article/4a44b3e2a4f646eaa098c5c76afb27b7
Autor:
Danni Gathot Harbowo, Aswan, Yahdi Zaim, Siti Khodijah Chaerun, Raudhatul Islam Chaerun, Widi Astuti, Tsutomu Sato
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Worldwide, silicified woods are found in many geological formations. Significantly, the organic materials of wood are no longer dominant; almost all wood fossils have been mineralized into inorganic silica materials. These unique geological
Externí odkaz:
https://doaj.org/article/0cbcde651fe0469fba5f6467b1e2cc40
Autor:
Natsuko Ishida, Ayano Katsura, Koichi Takagaki, Hiroshi Arakawa, Tsutomu Shimada, Satoshi Mizuno, Yoshimichi Sai, Yukio Kato, Hiroyuki Nakamura, Yukio Suga, Ryo Matsushita
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Hyposalivation is treated using oral cholinergic drugs; however, systemic side effects occasionally lead to discontinuation of treatment. We aimed to investigate the effects of transdermal pilocarpine on the salivary gland skin on
Externí odkaz:
https://doaj.org/article/0729e73cfbfd442d8f37c731457705ef